Journals / Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi / 2017 / Sayı: 1

Antimicrobial and Antioxidant Activities of Porphyridium cruentum

Porphyridium cruentum’un Antimikrobiyal ve Antioksidan Aktivitesi

Pages
1–7
Publication Date
2017-01-01
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Consequently, it was thought that P. cruentum could be considered as an important origin of natural compounds and a strong alternative to the other natural sources such as higher plants, because of potentially valuable antioxidant, antimicrobial constutients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In the present study, it was aimed to cultivate and analyze the potential antimicrobial and antioxidant activity of Porphyridium cruentum.
📊
Key Findings & Data:Besides, it showed the best activity against Staphylococcus aureus ATCC 6538P.
💡
Conclusion & Impact:Consequently, it was thought that P. cruentum could be considered as an important origin of natural compounds and a strong alternative to the other natural sources such as higher plants, because of potentially valuable antioxidant, antimicrobial constutients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Porphyridium cruentum · antimikrobiyal aktivite · antioksidan aktivite

Abstract

In the present study, it was aimed to cultivate and analyze the potential antimicrobial and antioxidant activity of Porphyridium cruentum. The biomass achieved from P. cruentum cultures was processed to obtain ethanol, n-hexane, methanol extracts and volatile components. Antimicrobial, antioxidant activities and total phenolic contents of the extracts were investigated by in vitro test methods. In addition, volatile compounds of P. cruentum were elucidated by GC/GCMS. When compared to the other solvent extracts, a potential antimicrobial activity was observed only in the n-hexane extract. Besides, it showed the best activity against Staphylococcus aureus ATCC 6538P. Volatile parts were active only against Pseudomonas aeruginosa ATCC 27853. The highest amount of total phenolic compounds was found as 62.45±2.0 mg Gallic Acid Equivalent/g Dry Weight mgGAE/gDW in the n-hexane extract. Statistically, a remarkable correlation was established between radical scavenging capacities and the total phenolic contents of the ethanol extracts. The level of antioxidant capacities varied according to the test methods. Consequently, it was thought that P. cruentum could be considered as an important origin of natural compounds and a strong alternative to the other natural sources such as higher plants, because of potentially valuable antioxidant, antimicrobial constutients.

Özet

Bu çalışmada, Porphyridium cruentum’un kültürünün yapılması, potansiyel antimikrobiyal ve antioksidan aktivitesinin analiz edilmesi amaçlandı. P. cruentum kültürlerinden elde edilen biyokütle, etanol, n-hekzan, metanol ekstreleri ve uçucu komponentlerin eldesi için işlemlerden geçirildi. Ekstrelerin antimikrobiyal, antioksidan aktiviteleri ve total fenolik içeriği in vitro test metodları ile araştırıldı. Ayrıca P. cruentum’un uçucu bileşenleri GC/GC-MS metodu ile aydınlatıldı. Diğer çözgen ekstreleri ile kıyaslandığında, sadece n-hekzan ekstresinde potansiyel antimikrobiyal aktivite gözlendi. Ayrıca, bu ekstre en iyi etkiyi Staphylococcus aureus ATCC 6538P’ye karşı gösterdi. Uçucu kısımları sadece Pseudomonas aeruginosa ATCC 27853’e karşı etkiliydi. Total fenolik bileş ikler 62,45±2,0 mg Gallik Asit Eşdeğer/g Kuru Ağırlık mgGAE/gKA değeri ile en yüksek oranda n-hekzan ekstresinde bulundu. İstatistiksel olarak, etanol ekstresinin, radikal süpürme kapasitesi ve total fenolik içeriği arasında önemli bir korelasyon olduğu tespit edildi. Ekstrelerin antioksidan aktivite düzeyi test metoduna bağlı olarak farklılıklar gösterdi. Sonuç olarak, P. cruentum’un, potansiyel değerli antioksidan, antimikrobiyal içeriği ile doğal bileşiklerin önemli bir orijini ve yüksek bitkiler gibi diğer doğal kaynaklara güçlü bir alternatif olarak kabul edilebileceği düşünüldü.

🔖

Cite This Article

YILMAZ, F. F., DEMİREL, Z., KARABAY-YAVASOGLU, N. U., OZDEMİR, G., CONK-DALAY, M. (2017). Antimicrobial and Antioxidant Activities of Porphyridium cruentum. Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi, Sayı: 1, 1–7. https://ajindex.com/articles/762325

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Apt KE, Behrens PW: Commerc al Developments n M croalgal B otechnology. Journal of Phycology 1999, 35: 215-226.
  2. Ördög V, Stirk WA, Lenobel R, Bancirova M, Strnad M, Staden J, Szigeti J, Nemeth L: Screening microalgae for some potentially useful agricultural and pharmaceutical secondary metabolites. Journal of Applied Phycology 2004, 16: 309-314.
  3. Spolaore P, Joannis-Cassan C, Duran E, Isambert A: Commercial applications of microalgae. Journal of Bioscience and Bioengineering 2006, 101: 87-96. Vonshak A. Porphyridium. In: Borowitzka MA, Borowitzka LJ. (eds), Microalgal Biotechnology. Cambridge University Press;
  4. Cambridge, UK. 1988: pp 122-134.
  5. Ginzberg A, Cohen M, Sod-Moriah UA, Shany S, Rosenshtrauch A, Arad S(M): Chickens fed with biomass of the red microalga Porphyridium sp. have reduced blood cholesterol level and modified fatty acid composition in egg yolk. Journal of Applied Phycology 2000, 12: 325-330. Dufosse’ L, Galaup P, Yaron A, Arad S (M), Blanc PK, Murthy NC, Ravishankar GA: Microorganisms and microalgae as sources of pigments for food use: a scientific oddity or an industrial reality? Trends in Food Science and Technology 2005, 16: 389-406.
  6. Huleihel M, Ishanu V, Tal J, Arad S(M): Antiviral Effect of Red Microalgal Polysaccharides on Herpes simplex and Varicella zoster Viruses. Journal of Applied Phycology 2001, 13: 127-134. Bergé JP, Debiton E, Dumay J, Durand P, Barthomeuf CJ: In vitro anti-inflammatory and anti- proliferative activity of sulfolipids from the red alga Porphyridium cruentum. Agricultural Food Chemistry 2002, 50: 6227-6232.
  7. Siriwardhana N, Lee K-W, Jeon Y-J, Kim S-H, Haw J-W: Antioxidant activity of Hizikia fusiformis on reactive oxygen species scavenging and lipid peroxidation inhibition. Food Science and Technology International 2003, 9: 339-346.
  8. Velioglu YS, Mazza G, Gao L, Oomah BD: Antioxidant activity and total phenolics in selected fruits, vegetables, and grain products. Journal of Agricultural and Food Chemistry 1998, 46: 4113- 4117. Li H-B, Cheng K-W, Wong C-C, Fan K-W, Chen F, Jiang Y: Evaluat on of ant ox dant capac ty and total phenol c content of d fferent fract ons of selected m croalgae. Food Chemistry 2007, 102: 771-776.
  9. Almajano MP, Carbo R, Lopez JA, Gordon MH: Antioxidant and antimicrobial activities of tea infusions. Food Chemistry 2008, 108: 55-63.
  10. Sroka Z, Cisowski W: Hydrogen peroxide scavenging, antioxidant and antiradical activity of some phenolics acids. Food and Chemical Toxicology 2003, 41: 753-758.