Journals / Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi / 2019 / Cilt: 39 - Sayı: 1

Usage Areas of Silica and Possıble Toxic Effects Due To Silica Exposure

Silikanın Kullanım Alanları ve Silika Maruziyetine Bağlı Olası Toksik Etkiler

Pages
17–29
Publication Date
2019-01-15
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This review aims to give a brief summary of the current information about usage and toxic effects of silica in humans and up date regulations about cristalline silica exposure in our country.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The earth’s crust contains approximately 12 % free crystalline silica and silicon (Si) is the second most common element after oxygen.
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Key Findings & Data:Therefore exposures to crystalline silica dust might occur in a large variety of occupations, including metal foundries, constructions and ceramic, quarry, pottery industries.
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Conclusion & Impact:This review aims to give a brief summary of the current information about usage and toxic effects of silica in humans and up date regulations about cristalline silica exposure in our country.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Silisyum dioksit · mesleki silika maruziyeti · silikozis

Abstract

The earth’s crust contains approximately 12 % free crystalline silica and silicon (Si) is the second most common element after oxygen. Therefore exposures to crystalline silica dust might occur in a large variety of occupations, including metal foundries, constructions and ceramic, quarry, pottery industries. Crystal- line silica exposure has been linked with silicosis, lung cancer and other pul- monary diseases. In recent years, studies conducted with silica-exposed workers have claimed that silica exposure have caused other cancers such as gastric, na- sopharyngeal, salivary gland cancer, liver cancer, bone cancer and brain cancer. Crystalline silica dust exposure in workers is still considered to be important health problem especially in developing countries. This review aims to give a brief summary of the current information about usage and toxic effects of silica in humans and up date regulations about cristalline silica exposure in our country.

Özet

Yerkabuğu % 12 serbest kristal silika içermektedir ve silisyum (Si), oksijenden sonra en yaygın ikinci elementtir. Bu nedenle kristal silika maruziyeti metal dökümcülük, inşaat, seramik, taş ocağı, çömlekçilik gibi çok çeşitli iş kollarında söz konusudur. Kristal silika maruziyeti silikozis, akciğer kanseri ve diğer solu- num sistemi hastalıkları ile ilişkilidir. Son yıllarda, kristal silika maruziyeti olan işçilerle yapılan çalışmalarla silika maruziyetinin, mide, nazofaringeal, tükürük bezi, karaciğer, kemik ve beyin kanseri gibi farklı kanserlere de neden olduğu iddia edilmektedir. Kristal silika tozuna maruziyet, özellikle gelişmekte olan ül- keler başta olmak üzere dünya çapında, halen önemli bir sağlık sorunu olarak kabul edilmektedir. Bu derleme, silikanın kullanım alanları ve insanlarda silika maruziyetine bağlı toksik etkiler hakkında güncel ve özet bilgilerin yanı sıra ül- kemizde kristal silika maruziyeti ile ilgili güncel yasal düzenlemeler hakkında bilgi sunmayı amaçlamaktadır.

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Cite This Article

ANLAR, H. G., BACANLI, M., BAŞARAN, N. (2019). Usage Areas of Silica and Possıble Toxic Effects Due To Silica Exposure. Hacettepe Üniversitesi Eczacılık Fakültesi Dergisi, Cilt: 39 - Sayı: 1, 17–29. https://ajindex.com/articles/762304

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