Journals / Balıkesir Medical Journal / 2020 / Cilt: 4 - Sayı: 3

The Relationship Between Hematological and Allergic Values in Children with Atopic Dermatitis

Atopik Dermatiti Olan Çocuklarda Hematolojik ve Alerjik Değerler Arasındaki İlişki

Pages
1–6
Publication Date
2020-11-27
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

High determination of these values will contribute to the reference of these values in future studies.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: Our aim in this study; In Atopic Dermatitis (AD), patients in the pediatric age group who applied to the Pediatric Dermatology Polyclinics of Sakarya University Training and Research Hospital (SUTRH), to determine neutrophil lymphocyte ratio (NLO), platelet lymphocyte ratio (TLO), eosinophil lymphocyte ratio (ELO) and serum total immune globobulin E (T-IgE) values and blood eosinophil count to investigate the relationship between AD and these parameters.
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Key Findings & Data:Materials and Methods: The data of the patients we included in the study were obtained retrospectively from the AD patients who applied between 01.01.2018 and 31.10.2019 through the hospital information management system (HIMS).
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Conclusion & Impact:High determination of these values will contribute to the reference of these values in future studies.
🔬Design:Research Article
📍Scope:2018 Verileri
⚙️Variables:atopik dermatit · total IgE değerleri · nötrofil lenfosit oranı

Abstract

Aim: Our aim in this study; In Atopic Dermatitis (AD), patients in the pediatric age group who applied to the Pediatric Dermatology Polyclinics of Sakarya University Training and Research Hospital (SUTRH), to determine neutrophil lymphocyte ratio (NLO), platelet lymphocyte ratio (TLO), eosinophil lymphocyte ratio (ELO) and serum total immune globobulin E (T-IgE) values and blood eosinophil count to investigate the relationship between AD and these parameters. Materials and Methods: The data of the patients we included in the study were obtained retrospectively from the AD patients who applied between 01.01.2018 and 31.10.2019 through the hospital information management system (HIMS). Those with allergic disease, infection or chronic disease were not included in the control group. Results: Of the 30 AD patients who met the study criteria, 8 were girls and 22 were boys, with an average age of 9.33 ± 5.84. In the control group, the average age of the patients was 12.6 girls and 18 boys, 10.69 ± 4.69. T-IgE values of AD patients were determined as 304.48±25.81 IU / mL, eosinophil levels were 1.39 ± 0.29 K / uL, NLO 2.23±1.19, TLO 123.69±41.99, ELO 0.133±0.111. T-IgE values of the control group were determined as 41.03±6.18 IU / mL, eosinophil levels on average 0.39±0.09 K / uL, NLO 1.73±0.61, 107.66±35.30, ELO 0.071±0.049. When AD patients and control groups were compared statistically, T-IgE, Eosinophil, NLO, ELO values were determined as (p 0.05). Conclusion: In our study, NLR, TLR, ELR and T-IgE values and blood eosinophil levels were found high in AD patients. It reveals that these parameters are important in the diagnosis and follow-up of this disease. High determination of these values will contribute to the reference of these values in future studies.

Özet

Amaç: Bu çalışmada amacımız; Sakarya Üniversitesi Eğitim ve Araştırma Hastanesi (SÜEAH) Pediatrik Dermatoloji Polikliniklerine müracaat eden pediatrik yaş grubunda Atopik Dermatit (AD) hastalarında, periferik kandan ölçülebilen nötrofil lenfosit oranı (NLO), trombosit lenfosit oranı (TLO), eozinofil lenfosit oranı (ELO) ile serum total immün globobülin E (T-IgE) değerleri ve kan eozinofil sayısını tespit etmek AD ile bu parametreler arasındaki ilişkiyi araştırmaktır. Gereç ve Yöntemler: Çalışmaya dahil ettiğimiz hastalara ait veriler 01.01.2018 ile 31.10.2019 tarihleri arasında müracaat eden AD hastalarından hastane bilgi yönetimi sistemi (HBYS) üzerinden retrospektif olarak elde edildi. Kontrol grubuna alerjik hastalığı, enfeksiyonu veya kronik bir hastalığı olanlar dahil edilmedi. Bulgular: Çalışma kriterlerine uyan 30 AD hastasının 8 kız, 22 erkek olup, yaş ortalaması 9.33±5.84 olarak tespit edildi. Kontrol grubunda 30 olgunun 12’si kız, 18’i erkek olmak üzere yaş ortalaması 10.69±4.69 olarak belirlendi. AD hastalarının T-IgE değerleri 304.48±25.81 IU/mL, eozinofil düzeyleri ortalama 1.39±0.29 K/uL, NLO 2.23±1.19, TLO 123.69±41.99, ELO 0.133±0.111 olarak tespit edildi. Kontrol grubunun T-IgE değerleri 41.03±6.18 IU/mL, eozinofil düzeyleri ortalama 0.39±0.09 K/uL, NLO 1.73±0.61, 107.66±35.30, ELO 0.071±0.049 olarak tespit edildi. AD hastaları ile kontrol grubu istatistiksel olarak karşılaştırıldığında T-IgE, Eozinofil, NLO, ELO değerleri arasında (p0.05) olarak tespit edildi. Sonuç: Çalışmamızda AD hastalarında NLO, TLO, ELO ile T-IgE değerleri ile kan eozinofil düzeyleri yüksek bulunmuştur. Bu parametrelerin bu hastalığın teşhis ve takibinde önemli olduğunu ortaya koymaktadır. Bu değerlerin yüksek saptanması, daha sonraki çalışmalarda bu değerlerin referans olarak alınabilmesine katkı sağlayacaktır

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Cite This Article

ÖZDİN, M. (2020). The Relationship Between Hematological and Allergic Values in Children with Atopic Dermatitis. Balıkesir Medical Journal, Cilt: 4 - Sayı: 3, 1–6. https://ajindex.com/articles/76114

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