Journals / Dental and Medical Journal - Review / 2019 / Cilt: 1 - Sayı: 3

APPLICATION OF DENTAL BOTOX

DENTAL BOTOKS UYGULAMALARI

Pages
89–102
Publication Date
2019-10-31
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although the therapeutic effect of CT is transient and relatively reliable, it is essential to have knowledge of the relevant anatomy and systemic and local side effects of the drugs administered to the face.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Botulinum is one of the most lethal toxins known and botulinum neurotoxin produced under anaerobic conditions by Clostridium Botulinum.
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Key Findings & Data:BT has been used in medicine and cosmetics since it has been learned that it causes muscle paralysis due to its effect on the neuromuscular junction (NMJ) where it blocks acetylcholine release in cholinergic neuron synapses.
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Conclusion & Impact:Although the therapeutic effect of CT is transient and relatively reliable, it is essential to have knowledge of the relevant anatomy and systemic and local side effects of the drugs administered to the face.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Botulinum toksin A · bruksizm · diş hekimliği

Abstract

Botulinum is one of the most lethal toxins known and botulinum neurotoxin produced under anaerobic conditions by Clostridium Botulinum. BT has been used in medicine and cosmetics since it has been learned that it causes muscle paralysis due to its effect on the neuromuscular junction (NMJ) where it blocks acetylcholine release in cholinergic neuron synapses. The most widely used BTA Botox® in the world has found its place in dentistry for aesthetic and therapeutic purposes such as temporomandibular disorders, bruxism, trigeminal neuralgia, oromandibular spasm, gummy smile, masseterhipertrofisi, sialorrhea. BTA injections are a much more minimally invasive method than radical surgical procedures and can be used as an adjunctive treatment. Although the therapeutic effect of CT is transient and relatively reliable, it is essential to have knowledge of the relevant anatomy and systemic and local side effects of the drugs administered to the face.

Özet

Botulinum toksini (BT) Clostridium Botulinum tarafından anaerobik koşullar altında üretilen en ölümcül toksinlerden biridir. BT, kolinerjik nöron sinapslarında asetilkolin salınımını bloke ettiği nöromüsküler kavşak (NMJ) üzerindeki etkisiyle kas felcine neden olduğunun öğrenilmesinden itibaren tıpta ve kozmetik alanda kullanılmaya başlanmıştır. Dünyada en yaygın olarak kullanılan BTA Botox®faciodental estetik ve terapötik amaçlara yönelik olarak diş hekimliğinde de kendine yer bulmuştur. BT’nın terapötik ve dentofasiyal estetik kullanımda etkili ve güvenli sonuçlar elde edilmiştir. Özellikle temporo mandibuler bozukluklar, bruksizm, gummy smile gibi vakalarda radikal cerrahiye göre çok daha az invaziv olması ve yardımcı tedavi olarak fayda sağlaması nedeniyle kendine yer edinmiştir. BT'nın terapötik etkisi geçici ve nispeten güvenli olmasına rağmen, ilgili anatomi ve yüze uygulanan ilaçların sistemik ve lokal yan etkileri hakkında bilgi sahibi olmak esastır.

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Cite This Article

ERDİL, D., FARSİANİ, H., BAĞIŞ, N. (2019). APPLICATION OF DENTAL BOTOX. Dental and Medical Journal - Review, Cilt: 1 - Sayı: 3, 89–102. https://ajindex.com/articles/750090

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References (16)

  1. Kerner J. Vergiftung durchver dorbene Würste.Tübinger Blätter Naturwissenschaften Arzneykunde1817
  2. Arnon SS, Schechter R, Inglesby TV, Henderson DA, Bartlett JG, Ascher MS, et al. Botulinum toxin as a biological weapon: Medical and public health management. JAMA 2001
  3. Park KS, Lee CH, Lee JW. JDentAnesthPainMed. 2016 Sep
  4. 16(3):151-157. 4. Burgen AS, Dickens F, Zatman LJ. The action of botulinum toxin on the neuro-muscular junction. J Physiol 1949
  5. Erbguth FJ. From poison tor emedy: The chequered history of botulinum toxin. J NeuralTransm (Vienna). 2008
  6. Scott A. Botulinum toxin injection to correct strabism. Trans Am Ophthalmol Soc. 1979
  7. Scott AB. Botulinum toxin injection of eye muscles to correct strabismus. Trans Am Ophthalmol Soc.1981
  8. Dastoor SF, Misch CE, Wang HL. Botulinum toxin (Botox) to enhance facial macroesthetics: A literatür ereview. J Oral Implantol. 2007
  9. 33(3):164-71. 9. Nayyar P., Kumar P., Nayyar PV. Botox: Broadening theHorizon of Dentistry.J ClinDiagnRes. 2014 Dec
  10. 8(12):ZE25-9. 10. Srivastava S, Kharbanda S, Pal US, Shah V. Applications of botulinum toxin in dentistry: A comprehensive review.Natl J MaxillofacSurg. 2015 Jul-Dec
  11. 6(2):152-9. 11. Kao I, Drachman DB, Price DL. Botulinum toxin: Mechanism of presynapticblockade. Science. 1976
  12. Simpson LL. The origin, structure, and pharmacological activity of botulinum toxin. PharmacolRev. 1981
  13. Jaspers GW, Pijpe J, Jansma J. The use of botulinum toxin type a in cosmetic facial procedures. Int J Oral MaxillofacSurg. 2011
  14. de Maio M. Therapeutic uses of botulinum toxin: From facial palsy to autonomic disorders. Expert OpinBiolTher 2008
  15. Lora VR, CanalesGde L, Goncalves LM, Meloto CB, Barbosa CM. Prevalence of temporomandibular disorders in post menopausal women and relationship with pain and HRT. Braz Oral Res. 2016.30(1): e100. 16.Schwartz M, Freund B. Botulinum Toxin a Therapy for Temporomandibular Disorders. Philadelphia, Pa: Lippincott Williams &Wilkins, 2002. 17.Schwartz M, Freund B. Treatment of temporomandibular disorders with botulinum toxin. Clin J Pain. 2002
  16. 18(6 Suppl):S198-203. 18. Castenada R. Occlusion. In: Kaplan A, Assael L (eds). Temporomandibular Disorders. Philadelphia, Pa: Saunders, 1992. 19.Freund B, Schwartz M, Symington JM. Theuse of botulinum toxin for the treatment of temporomandibular disorders: Preliminary findings. J Oral