Journals / Dental and Medical Journal - Review / 2022 / Cilt: 4 - Sayı: 3

Global review of hepatitis E virus infections transmitted by blood transfusion

Kan transfüzyonu ile bulaşan Hepatit E virüsü enfeksiyonlarının küresel düzeyde incelemesi

Pages
185–197
Publication Date
2022-10-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this study, it was aimed to review the global literature in terms of HEV transmitted by blood transfusion.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Although it was known that the most common route of transmission for hepatitis E virus (HEV) was the fecal-oral route in previous years, the possibility of transmission by blood transfusion has been advocated by many researchers recently.
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Key Findings & Data:This transmission is thought to cause mild to modarate hepatitis, especially in immunosuppressive patients.
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Conclusion & Impact:In this study, it was aimed to review the global literature in terms of HEV transmitted by blood transfusion.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Hepatit E virüsü · kan transfüzyonu · Genotip 3

Abstract

Although it was known that the most common route of transmission for hepatitis E virus (HEV) was the fecal-oral route in previous years, the possibility of transmission by blood transfusion has been advocated by many researchers recently. This transmission is thought to cause mild to modarate hepatitis, especially in immunosuppressive patients. It has been reported that especially HEV Genotype 3 is transmitted in blood transfusion. In this study, it was aimed to review the global literature in terms of HEV transmitted by blood transfusion.

Özet

Hepatit E virüsünün (HEV) önceki yıllarda en sık bulaş yolunun fekal-oral yol olduğu bilinmesine rağmen, son yıllarda birçok araştırmacı tarafından kan transfüzyonu ile bulaşma olasılığı savunulmaktadır. Bu geçişin, özellikle immünosupresif hastalarda hafif ile orta dereceli hepatite neden olduğu düşünülmektedir. Özellikle HEV Genotip 3'ün kan transfüzyonu ile bulaştığı bildirilmiştir. Bu çalışmada kan transfüzyonu ile bulaşan HEV açısından küresel literatürün gözden geçirilmesi amaçlanmıştır.

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Cite This Article

ALKAN, S., GÜRBÜZ, E., ŞAHİN, S., ÖZLÜ, C., ŞAHİNOĞLU, M. S. (2022). Global review of hepatitis E virus infections transmitted by blood transfusion. Dental and Medical Journal - Review, Cilt: 4 - Sayı: 3, 185–197. https://ajindex.com/articles/749493

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References (15)

  1. Goodnough LT, Panigrahi AK. Blood Transfusion Therapy. Med Clin North Am. 2017;101(2):431-447
  2. Takei T, Amin NA, Schmid G, Dhingra-Kumar N, Rugg D. Progress in global blood safety for HIV. J Acquir Immune Defic Syndr. 2009;52(Suppl 2):S127–131
  3. Perkins HA, Busch MP. Transfusion-associated infections: 50 years of relentless challenges and remarkable progress. Transfusion. 2010;50(10):2080-99
  4. Fauci AS, Morens DM. Zika virus in the Americas–yet another arbovirus threat. N Engl J Med. 2016; 374: 601-604
  5. Denner J, Pischke S, Steinmann E, Blümel J, Glebe D. Why all blood donations should be tested for hepatitis E virus (HEV). BMC Infect Dis. 2019;19(1):541
  6. Hartl J, Otto B, Madden RG, Webb G, Woolson KL, Kriston L, et al. Hepatitis E Seroprevalence in Europe: A Meta-Analysis. Viruses. 2016;8(8):211
  7. Sven Pischke, Jens Hiller, Marc Lütgehetmann, Susanne Polywka, Meike Rybczynski, Francis Ayuk, et al. Blood-borne Hepatitis E Virus Transmission: A Relevant Risk for Immunosuppressed Patients, Clinical Infectious Diseases. 2016; 63(4): 569–570
  8. Lhomme S, Dubois M, Abravanel F, Top S, Bertagnoli S, Guerin JL, Izopet J. Risk of zoonotic transmission of HEV from rabbits. J Clin Virol. 2013;58(2):357-362
  9. Izopet J. Virus de l’hépatite E et risque de transmission par transfusion [HEV and transfusion-recipient risk]. Ann Pharm Fr. 2018;76(2):89-96
  10. Niederhauser C, Widmer N, Hotz M, Tinguely C, Fontana S, Allemann G, et al. Current hepatitis E virus seroprevalence in Swiss blood donors and apparent decline from 1997 to 2016. Euro Surveill. 2018;23(35)
  11. Beale MA, Tettmar K, Szypulska R, Tedder RS. Ijaz S. Is there evidence of recent hepatitis E virus infection in English and north welsh blood donors? Vox Sang. 2011;100(3):340–342
  12. Vollmer T, Diekmann J, Johne R, Eberhardt M, Knabbe C, Dreier J. Novel approach for detection of hepatitis E virus infection in German blood donors. J Clin Microbiol. 2012;50(8):2708–2713
  13. Hewitt PE, Ijaz S, Brailsford SR, Brett R, Dicks S, Haywood B, et al. Hepatitis E virus in blood components: a prevalence and transmission study in Southeast England. Lancet. 2014;384(9956):1766–1773
  14. Boxall E, Herborn A, Kochethu G, Pratt G, Adams D, Ijaz S, et al. Transfusion-transmitted hepatitis E in a 'nonhyperendemic' country. Transfus Med. 2006;16(2):79–83
  15. Dreier J, Knabbe C, Vollmer T. Transfusion-transmitted hepatitis E: NAT screening of blood donations and infectious dose. Front Med (Lausanne). 2018;