Journals / Adıyaman Üniversitesi Sağlık Bilimleri Dergisi / 2018 / Cilt: 4 - Sayı: 3

Acute Renal Failure Due to Ethylene Glycol in a Patient Drunk Antifreeze: A Case Report.

Antifriz İçen Bir Hastada Etilen Glikole Bağlı Gelişen Akut Böbrek Yetmezliği: Olgu Sunumu.

Pages
1150–1156
Publication Date
2018-12-15
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The patient was referred to nephrology ward after treatment in the intensive care unit.

📌 3 Key Takeaways

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Objective & Hypothesis:SUMMARYFirst discovered by French chemist Charles Wurtz in 1859, ethylene glycol (EG) is a liquid alcohol which is odorless in its pure form, colorless, non-volatile, sweet in taste, syrup in consistency with its chemical formula being C2H6O2.
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Key Findings & Data:Minimal lethal dose of 95% solution of EG for an adult has been reported as 1.4 ml/kg based on body weight.
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Conclusion & Impact:The patient was referred to nephrology ward after treatment in the intensive care unit.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Etilen Glikol · Antifriz · intoksikasyon

Abstract

SUMMARYFirst discovered by French chemist Charles Wurtz in 1859, ethylene glycol (EG) is a liquid alcohol which is odorless in its pure form, colorless, non-volatile, sweet in taste, syrup in consistency with its chemical formula being C2H6O2. Although it is not toxic, it is an alcohol of which metabolites are toxic. Minimal lethal dose of 95% solution of EG for an adult has been reported as 1.4 ml/kg based on body weight. A case report was presented in this study who developed acute renal failure (ARF) due to EG. Fomepizole was used as antidote in 81 years old male patient presenting with coma, serious metabolic acidosis, and ARF following accidental ingestion of a few drops of antifreeze. The patient was referred to nephrology ward after treatment in the intensive care unit.

Özet

Etilen Glikol (EG) ilk kez 1859 yılında Fransız kimyager Charles Wurtz tarafından hazırlanmış, C2H6O2 formülüne sahip, saf halde kokusuz, renksiz, berrak, uçucu olmayan, tatlı, şurup kıvamında ve sıvı şeklinde bir alkoldür. EG kendisi toksik olmasa da, metabolitleri toksik olan bir alkoldür. EG’un %95’lik solusyonunun bir erişkin için minimum letal dozu, vücut ağırlığı esas alınarak 1.4 ml/kg olarak kaydedilmektedir. Bu çalışmada EG’e bağlı akut böbrek yetmezliği (ABY) gelişmiş bir olgu sunuldu. 81 yaşında erkek hastanın yanlışlıkla birkaç yudum antifriz içmesi sonrası görülen koma hali, ciddi metabolik asidoz ve akut böbrek yetmezliği (ABY) tablosu gelişen hastada antidot olarak fomepizol kullanıldı. Hasta yoğun bakım tedavisi sonrası nefroloji servisine devir edildi.

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Cite This Article

AYDIN, A. (2018). Acute Renal Failure Due to Ethylene Glycol in a Patient Drunk Antifreeze: A Case Report.. Adıyaman Üniversitesi Sağlık Bilimleri Dergisi, Cilt: 4 - Sayı: 3, 1150–1156. https://ajindex.com/articles/728098

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