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Journals / Adıyaman Üniversitesi Sağlık Bilimleri Dergisi / 2021 / Cilt: 7 - Sayı: 1

The effect of perfusion time on lactate level in cardiac surgery

Kardiyak cerrahide perfüzyon süresinin laktat düzeyi üzerine etkisi

Mustafa ABANOZ
Bişar AMAÇ
Mehmet TERCAN
Pages
45–53
Publication Date
2021-04-23
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Morbidity and mortality rates were found to be higher in hyperlactatemia group due to long cardiopulmonary bypass (CPB) duration.Conclusion: In our study, it was observed that the lactate level increased due to the prolongation of the perfusion time and the duration of aortic cross clamping.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: In our study, we aimed to compare the relationship between perfusion time and blood lactate levels of patients undergoing coronary artery bypass graft surgery.Materials and Methods: A total of 195 patients who underwent triple coronary artery bypass graft surgery were included in the study.
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Key Findings & Data:The patients were divided into two groups according to the blood lactate levels measured immediately after leaving the heart-lung machine.Results: There was a significant difference between the mean lactate levels of the groups (p<0.05).
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Conclusion & Impact:Morbidity and mortality rates were found to be higher in hyperlactatemia group due to long cardiopulmonary bypass (CPB) duration.Conclusion: In our study, it was observed that the lactate level increased due to the prolongation of the perfusion time and the duration of aortic cross clamping.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Kardiyopulmoner Bypass · Laktat · Perfüzyon Süresi.

Abstract

Aim: In our study, we aimed to compare the relationship between perfusion time and blood lactate levels of patients undergoing coronary artery bypass graft surgery.Materials and Methods: A total of 195 patients who underwent triple coronary artery bypass graft surgery were included in the study. The patients were divided into two groups according to the blood lactate levels measured immediately after leaving the heart-lung machine.Results: There was a significant difference between the mean lactate levels of the groups (p<0.05). There was a significant difference between "perfusion times" in both groups determined according to lactate levels (p<0.05). Morbidity and mortality rates were found to be higher in hyperlactatemia group due to long cardiopulmonary bypass (CPB) duration.Conclusion: In our study, it was observed that the lactate level increased due to the prolongation of the perfusion time and the duration of aortic cross clamping.

Özet

Amaç: Çalışmamızda koroner arter bypass greft ameliyatı olan hastaların perfüzyon süresi ile hastaların kan laktat düzeyleri arasındaki ilişkinin karşılaştırılması amaçlanmıştır.Gereç ve Yöntem: Çalışmaya üçlü koroner arter bypass greft ameliyatı olan toplam 195 hasta dahil edildi. Hastalar kalp-akciğer makinesinden ayrıldıktan hemen sonra ölçülen kan laktat düzeylerine göre iki gruba ayrıldı.Bulgular: Grupların ortalama laktat düzeyleri arasında anlamlı fark vardı (p<0,05). Laktat düzeylerine göre belirlenen her iki grubunda ''perfüzyon süreleri'' arasında anlamlı fark vardı (p<0,05). Uzun kardiyopulmoner bypass (KPB) süresine bağlı oluşan hiperlaktatemili grupta morbidite ve mortalite oranının daha yüksek olduğu görüldü.Sonuç: Çalışmamızda perfüzyon süresinin ve aortik kross klemp süresinin uzamasına bağlı olarak laktat düzeyinin de artığı görülmüştür.

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Cite This Article

ABANOZ, M., AMAÇ, B., TERCAN, M. (2021). The effect of perfusion time on lactate level in cardiac surgery. Adıyaman Üniversitesi Sağlık Bilimleri Dergisi, Cilt: 7 - Sayı: 1, 45–53. https://ajindex.com/articles/727980

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