Journals / Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2021 / Cilt: 54 - Sayı: 2

Evaluation of the predictivity of antenatal screening test parameters in pregnant women who had stillbirth due to intrauterine fetal demise

İntrauterin fetal ölüm nedeniyle ölü doğum gerçekleştiren gebe kadınlarda antenatal tarama testi parametrelerinin fetal ölüm üzerine olan prediktivitesinin değerlendirilmesi

Pages
292–298
Publication Date
2021-08-31
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Correlation analysis was performed using Spearman's correlation test.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: It was aimed to evaluate the predictivity of antenatal screening test parameters of pregnant women who had stillbirth due to intrauterine fetal demise according to maternal age and gestational birth weeks by retrospectively analysis in our study.
📊
Key Findings & Data:Material and Methods: This retrospective cohort study included a total of 394 pregnant women who had a stillbirth due to intrauterine fetal demise at 20 weeks of gestation or later at the University of Health Sciences, Ankara Dr.
💡
Conclusion & Impact:Correlation analysis was performed using Spearman's correlation test.
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:antenatal tarama testleri · intrauterin fetal ölüm · ölü doğum

Abstract

Objective: It was aimed to evaluate the predictivity of antenatal screening test parameters of pregnant women who had stillbirth due to intrauterine fetal demise according to maternal age and gestational birth weeks by retrospectively analysis in our study. Material and Methods: This retrospective cohort study included a total of 394 pregnant women who had a stillbirth due to intrauterine fetal demise at 20 weeks of gestation or later at the University of Health Sciences, Ankara Dr. Zekai Tahir Burak Women Health Education and Research Hospital between January 1, 2017, and June 15, 2019. Patients' demographic characteristics, birth characteristics, and antenatal screening test (combined, triple test) parameters (nuchal transparency [NT], free beta-human coronic gonadotropin [β-hCG], plasma protein-A [PAPP-A], hCG, unconjugated estriol [uE3], serum alpha-fetoprotein [ΑFP] multiples of median [MoM] values) were compared in separate groups of under and above 35 years of age and 20-34 weeks and above 34 weeks of gestation. Additionally, the correlation of antenatal screening test parameters with gestational week was evaluated. Data analysis was carried out using the SPSS version 26.0 statistical software package. Kolmogorov-Smirnov, Mann-Whitney U and Pearson Chi-Square tests were used for statistical analyses. Correlation analysis was performed using Spearman's correlation test. A p-value of

Özet

Amaç: Çalışmamızda intrauterin fetal ölüm nedeniyle ölü doğum gerçekleştirmiş gebe kadınlara ait antenatal tarama testi parametrelerinin retrospektif incelenerek maternal yaş ve doğum haftalarına göre fetal ölüm üzerine olan prediktivitesinin değerlendirilmesi amaçlandı. Gereç ve yöntemler: Bu retrospektif kohort çalışmaya, 1 Ocak 2017-15 Haziran 2019 tarihleri arasında Sağlık Bilimleri Üniversitesi, Ankara Dr. Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi’nde 20. gebelik haftası ve üzerinde intrauterin fetal ölüm nedeniyle ölü doğum gerçekleştirmiş olan toplam 394 gebe kadın dahil edildi. Hastalara ait demografik özellikler, doğum karakteristikleri ve antenatal tarama testi (ikili, üçlü test) parametreleri (nukal saydamlık [NT], serbest beta insan koryonik gonadotropin [β-hCG], gebelikle ilişkili plazma protein-A [PAPP-A], hCG, ankonjuge östriol [uE3], serum alfa fetoprotein [ΑFP] ortalamanın katları [MoM] değerleri) 35 yaş altı ve üstü ile 20-34. ve 34 üzeri gebelik haftalarına göre ayrı ayrı gruplar şeklinde karşılaştırıldı. Ayrıca antenatal tarama test parametrelerinin doğum haftası ile korelasyonu değerlendirildi. Verilerin analizi SPSS 26.0 istatistik paket programı kullanılarak yapıldı. İstatistiksel analizlerde Kolmogorov-Smirnov, Mann-Whitney U ve Pearson Ki-Kare testleri kullanıldı. Korelasyon analizi Spearman testi ile yapıldı. p

🔖

Cite This Article

EROL, S. A., ALTINBOĞA, O., TANACAN, A., ÇAĞLAR, A., USTUN, Y., ÖZGÜ-ERDİNÇ, A. S. (2021). Evaluation of the predictivity of antenatal screening test parameters in pregnant women who had stillbirth due to intrauterine fetal demise. Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 54 - Sayı: 2, 292–298. https://ajindex.com/articles/712656

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Management of Stillbirth: Obstetric Care Consensus No, 10. Obstetrics and gynecology. 2020;135(3):e110-e32
  2. World Health Organization (WHO). Stillbirths. https://www.who.int/maternal_child_adolescent/epidemiology/stillbirth/en/ (Accessed on March 09, 2020)
  3. Centers for Disease Control and Preventation, What is Stillbirth? https://www.cdc.gov/ncbddd/stillbirth/facts.html (Accessed on February 25, 2020)
  4. Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet (London, England). 2016;388(10053):1725-74
  5. MBRRACE-UK Perinatal Mortality Surveillance Report, UK Perinatal Deaths for Births from January to December 2018 https://www.npeu.ox.ac.uk/assets/downloads/mbrrace-uk/reports/perinatal-surveillance-report-2018/MBRRACE-UK_Perinatal_Surveillance_Report_2018_-_final_v3.pdf (Accessed on December, 2020)
  6. Dongarwar D, Aggarwal A, Barning K, Salihu HM. Trends in Stillbirths and Stillbirth Phenotypes in the United States: An Analysis of 131.5 Million Births. International journal of MCH and AIDS. 2020;9(1):146-8
  7. Reinebrant HE, Leisher SH, Coory M, Henry S, Wojcieszek AM, Gardener G, et al. Making stillbirths visible: a systematic review of globally reported causes of stillbirth. BJOG: an international journal of obstetrics and gynaecology. 2018;125(2):212-24
  8. Aminu M, Bar-Zeev S, van den Broek N. Cause of and factors associated with stillbirth: a systematic review of classification systems. Acta obstetricia et gynecologica Scandinavica. 2017;96(5):519-28
  9. Hoyert DL, Gregory EC. Cause of Fetal Death: Data From the Fetal Death Report, 2014. National vital statistics reports: from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System. 2016;65(7):1-25
  10. Groen H, Bouman K, Pierini A, Rankin J, Rissmann A, Haeusler M, et al. Stillbirth and neonatal mortality in pregnancies complicated by major congenital anomalies: Findings from a large European cohort. Prenatal diagnosis. 2017;37(11):1100-11
  11. Starikov R, Dudley D, Reddy UM. Stillbirth in the pregnancy complicated by diabetes. Current diabetes reports. 2015;15(3):11
  12. Townsend R, Manji A, Allotey J, Heazell A, Jorgensen L, Magee LA, et al. Can risk prediction models help us individualise stillbirth prevention? A systematic review and critical appraisal of published risk models