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Journals / Sakarya Tıp Dergisi / 2022 / Cilt: 12 - Sayı: 3

The Relationship of Mitral Anular Calcification with Mortality and Myocardial Injury in COVID-19 Patients

COVID-19 Hastalarında Mitral Anüler Kalsifikasyonun Mortalite ve Miyokard Hasarı ile İlişkisi

Savaş ÖZER
Eser BULUT
Ercan AYDIN
Dilek Cahide HAZNEDAR KIRCI
Ali Gökhan ÖZYILDIZ
Mustafa PEKER
Oguzhan Ekrem TURAN
Pages
544–551
Publication Date
2022-09-29
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results: Male gender, advanced age (>65), hypertension, diabetes mellitus, chronic obstructive pulmonary disease, chronic kidney disease (CKD), coronary artery disease, heart failure and atrial fibrillation rates were statistically higher in the mortality group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Coronavirus disease-2019 (COVID-19) can particularly affect the respiratory and cardiovascular systems and cause serious mortality.
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Key Findings & Data:We aimed to evaluate the effect of MAC on myocardial injury (MI) and mortality, which can develop secondary to COVID-19 infection.
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Conclusion & Impact:Results: Male gender, advanced age (>65), hypertension, diabetes mellitus, chronic obstructive pulmonary disease, chronic kidney disease (CKD), coronary artery disease, heart failure and atrial fibrillation rates were statistically higher in the mortality group (p
🔬Design:Research Article
📍Scope:2019 Verileri
⚙️Variables:Koronavirüs · COVID-19 enfeksiyonu · mitral anüler kalsifikasyon

Abstract

Objective: Coronavirus disease-2019 (COVID-19) can particularly affect the respiratory and cardiovascular systems and cause serious mortality. Mitral annular calcification (MAC) is a mitral valve pathology associated with cardiac mortality. We aimed to evaluate the effect of MAC on myocardial injury (MI) and mortality, which can develop secondary to COVID-19 infection. Materials and Methods: After applying the exclusion criteria, thorax computed tomography (CT) images of the remaining 1151 consecutive COVID-19 patients were evaluated. Calculation of MAC scores was done by two expert radiologists blinded to the study data. MI was defined as those with hs-TnI level (≥34 ng/dl). Patients included in the study were classified as having mortality and not occurring. Results: Male gender, advanced age (>65), hypertension, diabetes mellitus, chronic obstructive pulmonary disease, chronic kidney disease (CKD), coronary artery disease, heart failure and atrial fibrillation rates were statistically higher in the mortality group (p

Özet

Amaç: Koronavirüs hastalığı-2019 (COVID-19) özellikle solunum ve kardiyovasküler sistemleri etkileyerek ciddi mortaliteye neden olabilir. Mitral halka şeklindeki kalsifikasyon (MAC), kardiyak mortalite ile ilişkili bir mitral kapak patolojisidir. Bu çalışmada, MAC'ın COVID-19 enfeksiyonuna sekonder gelişebilen miyokard hasarı (MI) ve mortalite üzerine etkisini değerlendirmeyi amaçladık. Gereç ve Yöntemler: Dışlama kriterleri uygulandıktan sonra geriye kalan 1151 ardışık COVID-19 hastasının toraks bilgisayarlı tomografi (BT) görüntüleri değerlendirildi. MAC puanlarının hesaplanması, çalışma verilerine kör olan iki uzman radyolog tarafından yapıldı. MI, hs-TnI düzeyi (≥34 ng/dl) olanlar olarak tanımlandı. Çalışmaya dahil edilen hastalar mortalitesi olan ve oluşmayan olarak sınıflandırıldı. Bulgular: Mortalite grubunda erkek cinsiyet, ileri yaş (>65), hipertansiyon, diabetes mellitus, kronik obstrüktif akciğer hastalığı, kronik böbrek hastalığı (KKD), koroner arter hastalığı, kalp yetmezliği ve atriyal fibrilasyon oranları istatistiksel olarak daha yüksekti (p

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Cite This Article

ÖZER, S., BULUT, E., AYDIN, E., KIRCI, D. C. H., ÖZYILDIZ, A. G., PEKER, M., TURAN, O. E. (2022). The Relationship of Mitral Anular Calcification with Mortality and Myocardial Injury in COVID-19 Patients. Sakarya Tıp Dergisi, Cilt: 12 - Sayı: 3, 544–551. https://ajindex.com/articles/697796

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