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Journals / Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi / 2022 / Cilt: 19 - Sayı: 3

The effect of low molecular weight heparin on the systemic immune-inflammation index in pregnancy

Gebelerde düşük molekül ağırlıklı heparin kullanımının sistemik immün-inflamasyon indeksi üzerine etkisi

Deniz OLUKLU
Şule GÖNCÜ AYHAN
Mehmet KEVEN
Dilek SAHİN
Pages
1344–1349
Publication Date
2022-09-30
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Results After the usage of LMWH , mean erythrocyte distribution width (RDW), mean platelet volume (MPV), mean platelet distribution width (PDW) , NLR, and SII increased and platecrite, and LMR decreased significantly (p

📌 3 Key Takeaways

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Objective & Hypothesis:Aim The aim of this study was to investigate the effect of low molecular weight heparin (LMWH) use on inflammatory markers.
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Key Findings & Data:Material and Methods: Fifty-seven pregnant women were enrolled in this study.
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Conclusion & Impact:Results After the usage of LMWH , mean erythrocyte distribution width (RDW), mean platelet volume (MPV), mean platelet distribution width (PDW) , NLR, and SII increased and platecrite, and LMR decreased significantly (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Düşük molekül ağırlıklı heparin · hemogram · OTH

Abstract

Aim The aim of this study was to investigate the effect of low molecular weight heparin (LMWH) use on inflammatory markers. Material and Methods: Fifty-seven pregnant women were enrolled in this study. Neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), lymphocyte monocyte ratio (LMR), and systemic immune-inflammation index (SII) (Neutrophil x Platelet / Lymphocyte) were calculated using complete blood count parameters. These parameters were compared before and after one month usage of LMWH. . Results After the usage of LMWH , mean erythrocyte distribution width (RDW), mean platelet volume (MPV), mean platelet distribution width (PDW) , NLR, and SII increased and platecrite, and LMR decreased significantly (p

Özet

Amaç Gebelerde Düşük Molekül Ağırlıklı Heparin (DMAH) kullanımı sonrası inflamasyon belirteçlerinin değişiminin saptanması amaçlanmıştır. Gereç ve Yöntemler Gebeliğinde DMAH kullanan 57 hastanın DMAH kullanımı öncesi ve bir ay sonrası hemogram tetkikindeki parametreler kullanılarak hesaplanan, NLO (Nötrofil Lenfosit Oranı), TLO (Trombosit Lenfosit Oranı), LMO (Lenfosit Monosit Oranı) ve SII (Sistemik İmmün-inflamasyon İndeks) (Nötrofil x Trombosit / Lenfosit) karşılaştırıldı. Bulgular DMAH kullanımı sonrasında OEDG (Ortalama eritrosit dağılım genişliği), OTH (ortalama trombosit hacmi), OTDG (Ortalama trombosit dağılım genişliği), NLO ve SII anlamlı olarak artarken; platekrit, LMO anlamlı olarak azalmış olarak saptandı (p

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Cite This Article

OLUKLU, D., AYHAN, Ş. G., KEVEN, M., SAHİN, D. (2022). The effect of low molecular weight heparin on the systemic immune-inflammation index in pregnancy. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi, Cilt: 19 - Sayı: 3, 1344–1349. https://ajindex.com/articles/676474

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