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Journals / Hacettepe Üniversitesi Sağlık Bilimleri Fakültesi Dergisi / 2014 / Cilt: 1 - Sayı: 1

The Health Effects of Alpha Lipoic Acid

Alfa Lipoik Asidin Sağlık Üzerine Etkileri

Armağan Yürük
Aylin Ayaz
Pages
11–23
Publication Date
2014-12-10
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Because of its effects on oxidative stres and glucose balance lipoic acid may prevent diabetic complications and neuro degenerative diseases and their progression.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Alpha-lipoic acid is a natural substance found in a variety of foods and also synthesized in the human body.
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Key Findings & Data:Both alpha lipoic acid and its reduced form dihydrolipoic acid are antioxidants.
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Conclusion & Impact:Because of its effects on oxidative stres and glucose balance lipoic acid may prevent diabetic complications and neuro degenerative diseases and their progression.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Alfa lipoik asit · dihidrolipoik asit · antioksidan

Abstract

Alpha-lipoic acid is a natural substance found in a variety of foods and also synthesized in the human body. Both alpha lipoic acid and its reduced form dihydrolipoic acid are antioxidants. The antioxidant mechanisms are scavenging free radicals, chelating with metals, regenerating other antioxidants and repairing oxidative damage. It reduces heavy metal toxication by chelating. Lipoic acid supports blood glucose balance by effecting insülin signal pathways. Because of its effects on oxidative stres and glucose balance lipoic acid may prevent diabetic complications and neuro degenerative diseases and their progression.

Özet

Alfa lipoik asit, çeşitli yiyeceklerde bulunan ve vücutta da sentezlenebilen bir maddedir. Hem alfa lipoik asit hem de indirgenmiş formu olan dihidrolipoik asit antioksidan özellik göstermektedir. Bu antioksidan etkisini serbest radikal yakalama, metallerle şelat oluşturma, diğer antioksidanların yeniden kullanılabilirliğini arttırma ve oksidatif hasarı onarma mekanizmaları yardımıyla gerçekleştirir. Ağır metallerle şelat oluşturarak toksik etkilerini azaltabilmektedir. İnsülinin sinyal yolaklarını etkileyerek kan glikozu dengesinin sağlanmasına yardımcı olur. Oksidatif stres ve glikoz dengesi üzerindeki etkileri nedeniyle diyabetik komplikasyonların ve nörodejeneratif hastalıkların oluşumunu ve ilerlemesini önleyebilmektedir

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Cite This Article

Yürük, A., Ayaz, A. (2014). The Health Effects of Alpha Lipoic Acid. Hacettepe Üniversitesi Sağlık Bilimleri Fakültesi Dergisi, Cilt: 1 - Sayı: 1, 11–23. https://ajindex.com/articles/670970

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