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Journals / Gümüşhane Üniversitesi Fen Bilimleri Dergisi / 2016 / Cilt: 6 - Sayı: 1

The Effect Of Cypermethrin On Oxidative Stress Parameters In Israeli carp (Carassius gibelio Bloch, 1782) Fish

İsrail Sazanı (Carassius gibelio Bloch, 1782) Balıklarına Uygulanan Cypermethrin’in Oksidatif Stres Parametreleri Üzerine Etkileri

Hamit USLU
Gözde ATİLA
Yusuf ERSAN
Zaide ÖZDEN
Pages
41–46
Publication Date
2016-01-31
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results showed significant increase in MDA of the liver and muscle tissues (p<0.001 level in all groups) with serum samples (p<0.01, p<0.001, p<0.001 respectively).

📌 3 Key Takeaways

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Objective & Hypothesis:The present study was aimed to determine changes in the levels of oxidative stress markers such as Malondialdehyde (MDA) and the antioxidant levels such as Glutathione (GSH) and Superoxide Dismutase (SOD) in different organs such as liver, kidney, muscle, and serum samples of Carassius gibelio exposure to low (1 µgL-1), middle (1.5 µgL-1) and high (2 µgL-1) doses Cypermethrin for 96 h.
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Key Findings & Data:The results showed significant increase in MDA of the liver and muscle tissues (p<0.001 level in all groups) with serum samples (p<0.01, p<0.001, p<0.001 respectively).
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Conclusion & Impact:The result of the study showed that the very important corruption balance between oxidants and antioxidants depend on Cypermethrin exposured even in short period.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Antioksidan · Oksidan · Oksidatif stres

Abstract

The present study was aimed to determine changes in the levels of oxidative stress markers such as Malondialdehyde (MDA) and the antioxidant levels such as Glutathione (GSH) and Superoxide Dismutase (SOD) in different organs such as liver, kidney, muscle, and serum samples of Carassius gibelio exposure to low (1 µgL-1), middle (1.5 µgL-1) and high (2 µgL-1) doses Cypermethrin for 96 h. The results showed significant increase in MDA of the liver and muscle tissues (p<0.001 level in all groups) with serum samples (p<0.01, p<0.001, p<0.001 respectively). SOD levels was determined that the significant decrease in liver (p<0.05, p<0.01, p<0.001 respectively), muscle tissues (p<0.001 level in medium and high doses) and serum samples (p<0.01 level in high dose). Moreover GSH levels was detected that significant decrease in the muscle (p<0.001, p<0.001, p<0.05 respectively) and serum samples (p<0.01 level in high doses). We did not observe a significant difference of the oxidant and antioxidants levels in the kidney tissue (p>0.05). The uncontrolled, insensible and unnecessary usage of pesticides such as Cypermethrin can be use serious hazard to the environment and public health. The result of the study showed that the very important corruption balance between oxidants and antioxidants depend on Cypermethrin exposured even in short period.

Özet

Bu çalışmada 96 saat boyunca düşük (1 µgL-1), orta (1.5 µgL-1) ve yüksek (2 µgL-1) dozlarda Cypermethrin maruziyetinde Carassius gibelio’nun karaciğer, böbrek ve kas gibi farklı dokuları ile serum örneklerindeki oksidatif stres belirteçlerinden olan Malondialdehit (MDA) ile Glutatyon (GSH) ve Süperoksit Dismutaz (SOD) gibi antioksidanların seviyelerinin değişikliklerini belirlemek amaçlanmıştır. Bulgular MDA’nın karaciğer ve kas dokuları (tüm gruplarda; p<0.001 düzeyinde) ile serum örneklerinde (sırasıyla; p<0.01, p<0.001, p<0.001) önemli şekilde artırdığını göstermiştir. SOD seviyelerinin karaciğer (sırasıyla; p<0.05, p<0.01, p<0.001) ve kas dokuları (orta ve yüksek dozlarda; p<0.001 düzeyinde) ile serum örneklerinde (yüksek dozda; p<0.01 düzeyinde) önemli şekilde azaldığı belirlenmiştir. Ayrıca GSH seviyelerinin de kas (sırasıyla; p<0.001, p<0.001, p<0.05) ve serum örneklerinde (yüksek dozda; p<0.01 düzeyinde) önemli şekilde azaldığı tespit edilmiştir. Böbrek dokusunun oksidan ve antioksidan seviyelerinde önemli bir değişiklik gözlemlemedik (p>0.05). Cypermethrin gibi pestisitlerin kontrolsüz, bilinçsiz ve gereksiz kullanımı çevre ve halk sağlığında ciddi tehlikelere yol açabilmektedir. Bu çalışmanın sonuçları kısa süreli Cypermethrin maruziyetinde bile oksidan ve antioksidanlar arasındaki dengede oldukça önemli bozulmalar olduğunu göstermektedir.

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Cite This Article

USLU, H., ATİLA, G., ERSAN, Y., ÖZDEN, Z. (2016). The Effect Of Cypermethrin On Oxidative Stress Parameters In Israeli carp (Carassius gibelio Bloch, 1782) Fish. Gümüşhane Üniversitesi Fen Bilimleri Dergisi, Cilt: 6 - Sayı: 1, 41–46. https://ajindex.com/articles/668458

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