The Prevalence of Fibromyalgia in Patients with Restless Legs Syndrome

The patients with RLS had higher scores of mental health, social functioning, pain, and general perception of SF-36, and scale for the evaluation of quality of life (p=0.004; p=0.023; p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To determine the prevalence of fibromyalgia (FM) in patients with Restless legs syndrome (RLS), and to evaluate the relationship of FM and the scales of quality of life.Materials and Methods: Thirty patients aged between 18-65 years (20 females, 10 males) with RLS and 30 healthy control subjects (17 female, 13 male) participated in our study.

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Key Findings & Data:The Pittsburg Sleep Quality Index (PSQI), Beck Depression Inventory, Beck Anxiety Questionnaire, and Quality of Life Short form-36 (SF-36) were given to both the patient and control group.

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Conclusion & Impact:The patients with RLS had higher scores of mental health, social functioning, pain, and general perception of SF-36, and scale for the evaluation of quality of life (p=0.004; p=0.023; p

🔬Design:Survey & Empirical Study

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Objective: To determine the prevalence of fibromyalgia (FM) in patients with Restless legs syndrome (RLS), and to evaluate the relationship of FM and the scales of quality of life.Materials and Methods: Thirty patients aged between 18-65 years (20 females, 10 males) with RLS and 30 healthy control subjects (17 female, 13 male) participated in our study. The patients were assessed using the the RLS Severity Rating Scale. The Pittsburg Sleep Quality Index (PSQI), Beck Depression Inventory, Beck Anxiety Questionnaire, and Quality of Life Short form-36 (SF-36) were given to both the patient and control group. The American College of Rheumatology criteria were used to diagnose FM.Results: The average age of the patients was 44.73±11.23 years, the average age of the control group was 46.00±12.23 years. The prevalence of FM was 36.7% in the patient group and 6.7% in the control group (p=0.01). PSQI, depression and anxiety scores were significantly worse in the patient group (p=0.0001; p=0.004; p=0.000). The patients with RLS had higher scores of mental health, social functioning, pain, and general perception of SF-36, and scale for the evaluation of quality of life (p=0.004; p=0.023; p

Özet

Amaç: Çalışmamızın amacı Huzursuz bacaklar sendromlu (HBS) hastalarda fibromiyalji (FM) sıklığını belirlemek, yaşam kalitesi ölçekleri ve FM arasındaki ilişkiyi değerlendirmektir.Gereç ve Yöntem: Çalışmamıza 18-65 yaş arasında HBS tanısı almış 30 hasta (20 kadın, 10 erkek) ve 30 sağlıklı kontrol (17 kadın, 13 erkek) katıldı. Hasta grubuna HBS Ağırlık Derecesi Ölçeği uygulanırken, hem hasta hem de kontrol grubuna Pittsburg Uyku Kalitesi İndeksi (PUKİ), Beck Depresyon Ölçeği, Beck Anksiyete Ölçeği ve Yaşam Kalitesi Kısa form-36 (KF-36) verildi. FM tanısı için Romatoloji Amerikan Koleji tarafından düzenlenen kriterler kullanıldı.Bulgular: Hastaların yaş ortalaması 44,73±11,23 yaş, kontrol grubun yaş ortalaması 46,00±12,23 yaş idi. Hastaların %36,7'sinde FM varken, kontrol grubunun %6,7'sinde vardı (p=0,01). Hastaların PUKİ, depresyon ve anksiyete skorları anlamlı olarak daha kötüydü (p=0,0001; p=0,004; p=0,000). Yaşam kalitesini değerlendirme ölçeğine (KF-36) göre ise HBS'si olanlarda enerji, ruhsal sağlık, sosyal fonksiyon, ağrı ve genel algı puanları anlamlı olarak daha yüksekken (p=0,004; p=0,023, p=0,0001; p=0,001; p=0,13), fiziksel ve emosyonel kısıtlılık puanları arasında kontrol grubu ile fark saptanmadı. Ancak HBS olanlarda ek olarak FM varlığı sadece vücut genel algı değerinde kötüleşmeye neden olmaktaydı (p=0,029). HBS ve FM bulguları olan hastalar hiçbir hastalığı olmayan grupla karşılaştırılınca en çok anksiyete puanlarında (üç kat) artma olduğu tespit edildi.Sonuç: Orta ve şiddetli HBS'li hastalarda FM sıktır (%36,67). HBS yaşam kalitesini bozmaktadır. Ancak iki hastalığın birlikteliği sadece hastaların kendi sağlıklarını değerlendirme skorlarını kötüleştirmekte ve en çok anksiyete skorlarını olumsuz etkilemektedir.

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Cite This Article

DÜZ, Ö. A., HANOĞLU, L., DEMİRCİ, S., CANTÜRK, E., TAŞKIN, D., POLAT, B., HELVACI, N. Y., PARLAKOĞLU, B., TAVLI, A. M., PINAR, A. D., ÖZER, F. F., ÇAKAR, E. (2022). The Prevalence of Fibromyalgia in Patients with Restless Legs Syndrome. Türk Nöroloji Dergisi, Cilt: 22 - Sayı: 4, 161–166. https://ajindex.com/articles/655093

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References (9)

Allen RP, Picchietti DL, Garcia-Borreguero D, Ondo WG, Walters AS, Winkelman JW, Zucconi M, Ferri R, Trenkwalder C, Lee HB, International Restless Legs Syndrome Study G. Restless legs syndrome/Willis-Ekbom disease diagnostic criteria: updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria--history, rationale, description, and significance. Sleep Med 2014;15:860-873.
Karroum EG, Golmard JL, Leu-Semenescu S, Arnulf I. Painful restless legs syndrome: a severe, burning form of the disease. Clin J Pain 2015;31:459- 466. Allen RP, Earley CJ. The role of iron in restless legs syndrome. Mov Disord 2007;22(Suppl 18):S440-448. Edwards RR, Quartana PJ, Allen RP, Greenbaum S, Earley CJ, Smith MT. Alterations in pain responses in treated and untreated patients with restless legs syndrome: associations with sleep disruption. Sleep Med 2011;12:603- 609. Hoogwout SJ, Paananen MV, Smith AJ, Beales DJ, O'Sullivan PB, Straker LM, Eastwood PR, McArdle N, Champion D. Musculoskeletal pain is associated with restless legs syndrome in young adults. BMC Musculoskelet Disord 2015;16:294. Cho YW, Song ML, Earley CJ, Allen RP. Prevalence and clinical characteristics of patients with restless legs syndrome with painful symptoms. Sleep Med 2015;16:775-778.
Winkelman JW, Gagnon A, Clair AG. Sensory symptoms in restless legs syndrome: the enigma of pain. Sleep Med 2013;14:934-942.
Yunus MB, Aldag JC. Restless legs syndrome and leg cramps in fibromyalgia syndrome: a controlled study. BMJ 1996;312:1339. Stehlik R, Arvidsson L, Ulfberg J. Restless legs syndrome is common among female patients with fibromyalgia. Eur Neurol 2009;61:107-111.
Viola-Saltzman M, Watson NF, Bogart A, Goldberg J, Buchwald D. High prevalence of restless legs syndrome among patients with fibromyalgia: a controlled cross-sectional study. J Clin Sleep Med 2010;6:423-427.
Hornyak M, Sohr M, Busse M, Study G. Evaluation of painful sensory symptoms in restless legs syndrome: experience from two clinical trials. Sleep Med 2011;12:186-189.
Walters AS, LeBrocq C, Dhar A, Hening W, Rosen R, Allen RP, Trenkwalder C, International Restless Legs Syndrome Study G. Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome. Sleep Med 2003;4:121-132.
Buysse DJ, Reynolds CF, Monk TH, Berman SR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res 1989;28:193-213.
Beck AT, Steer RA, Brown GK.