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Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2010 / Cilt: 19 - Sayı: 2

Severe pancytopenia ınduced by low-dose methotrexate in a hemodialysis patient

Bir hemodiyaliz hastasında düşük doz metotreksat sonucu gelişen şiddetli pansitopeni

Ramazan ULU
Hüseyin ÇELİKER
Ayhan DOĞUKAN
İrem Pembegül YİĞİT
Yener YILDIZ
Pages
147–149
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

She recovered after folinic acid, granulocyte colony-stimulating factor, antibiotic and daily hemodialysis therapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Methotrexate has been used as an important alternative therapy in the treatment of various rheumatic diseases.
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Key Findings & Data:A 35-year-old woman undergoing hemodialysis developed severe stomatitis and pancytopenia after low-dose methotrexate treatment for rheumatoid arthritis.
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Conclusion & Impact:She recovered after folinic acid, granulocyte colony-stimulating factor, antibiotic and daily hemodialysis therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Methotrexate has been used as an important alternative therapy in the treatment of various rheumatic diseases. It is primarily cleared by the kidney. Life-threatening marrow suppression in hemodialysis patients has been reported. A 35-year-old woman undergoing hemodialysis developed severe stomatitis and pancytopenia after low-dose methotrexate treatment for rheumatoid arthritis. She recovered after folinic acid, granulocyte colony-stimulating factor, antibiotic and daily hemodialysis therapy.

Özet

Metotreksat, çeşitli romatizmal hastalıkların tedavisinde kullanılan önemli bir seçenek olup temel atılım yolu böbreklerdir. Hemodiyaliz tedavisi alan hastalarda metotreksat kullanımı sırasında ciddi pansitopeni görülebilmektedir. Bu makalede, hemodiyaliz programında olan ve romatoid artrit tedavisi için düşük doz metotreksat kullanımı sonucu şiddetli pansitopeni ve stomatit gelişen; folinik asit, granülosit koloni uyarıcı faktör, antibiyotik ve günlük diyaliz sonrası düzelen 35 yaşındaki kadın olguyu sunduk.

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Cite This Article

ULU, R., ÇELİKER, H., DOĞUKAN, A., YİĞİT, İ. P., YILDIZ, Y. (2022). Severe pancytopenia ınduced by low-dose methotrexate in a hemodialysis patient. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 19 - Sayı: 2, 147–149. https://ajindex.com/articles/655029

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References (1)

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