Journals / Turkish Neurosurgery / 2014 / Cilt: 24 - Sayı: 5

Evaluating the Diagnostic Accuracy of CT Perfusion in Patients with Cerebral Vasospasm After Aneurysm Rupture: A Meta-Analysis

Anevrizma Rüptüründen Sonra Serebral Vazospazmlı Hastalarda BT Perfüzyonun Tanısal Doğruluğunun Değerlendirilmesi: Bir Meta Analiz

Pages
757–762
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As CTP parameters, CBF and MTT quantitatively evaluate brain parenchymal perfusion.

📌 3 Key Takeaways

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Objective & Hypothesis:AIm: Computed tomography perfusion (CTP) has recently been used to identify regions of potential ischemia due to cerebral vasospasm, and CTP parameters are able to quantitatively evaluate brain parenchymal perfusion.
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Key Findings & Data:We performed a meta-analysis as an update of a previous paper published in 2010 and aimed at evaluating the diagnostic accuracy of CTP and CTP parameters for vasospasm after aneurysm rupture.mATERIAL and mETHods: Relevant articles published between January 2005 and May 2013 were systematically searched for analysis without language restrictions from the PubMed/MEDLINE, Embase, and Cochrane databases.
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Conclusion & Impact:As CTP parameters, CBF and MTT quantitatively evaluate brain parenchymal perfusion.
🔬Design:Lab & Field Experiment
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

AIm: Computed tomography perfusion (CTP) has recently been used to identify regions of potential ischemia due to cerebral vasospasm, and CTP parameters are able to quantitatively evaluate brain parenchymal perfusion. We performed a meta-analysis as an update of a previous paper published in 2010 and aimed at evaluating the diagnostic accuracy of CTP and CTP parameters for vasospasm after aneurysm rupture.mATERIAL and mETHods: Relevant articles published between January 2005 and May 2013 were systematically searched for analysis without language restrictions from the PubMed/MEDLINE, Embase, and Cochrane databases. The data of CTP parameters, including CBV, CBF, MTT and TTP, were extracted for analysis, and the pooled sensitivity, specificity, PLR, NLR, DOR and the sROC curve were determined. REsuLTs: Three relevant articles and a total of 98 patients were finally involved in the analysis. The pooled sensitivity, specificity, PLR, NLR, DOR, and AUC of CTP for diagnosing cerebral vasospasm were 94%, 90%, 8.22, 0.06, 141.09, and 0.9802, respectively. Through the evaluation of CTP parameters, MTT had a higher sensitivity (91%) while CBF had a higher specificity (93%). CoNCLusIoN: CT perfusion has a great diagnostic value to detect cerebral vasospasm compared with DSA in patients with aneurysmal subarachnoid hemorrhage (aSAH). As CTP parameters, CBF and MTT quantitatively evaluate brain parenchymal perfusion.

Özet

AmAÇ: Bilgisayar tomografi perfüzyon (BTP) yakın zamanlarda serebral vazospazm nedeniyle potansiyel iskemi bölgelerini tanımlamak için kullanılmıştır ve BTP parametreleri beyin parankim perfüzyonunu kantitatif olarak değerlendirebilir. 2010 yılında yayınlanan daha önceki bir yazının güncelleştirmesi olarak meta analiz yaptık ve anevrizma rüptürü sonrası vazospazm için BTP ve BTP parametrelerinin tanısal doğruluğunu değerlendirmeyi amaçladık. yÖNTEm ve GEREÇLER: Ocak 2005 ve Mayıs 2013 arasında yayınlanmış ilgili makaleler PubMed/MEDLINE, Embase, ve Cochrane veri tabanlarından dil sınırlaması olmadan sistematik olarak analiz için tarandı. CBV, CBF, MTT ve TTP de dahil olmak üzere BTP parametreleri verileri analiz için çıkarıldı ve toplanmış duyarlılık, özgüllük, PLR, NLR, DOR ve sROC eğrileri belirlendi. BuLGuLAR: İlgili üç makale ve toplam 98 hasta analize dahil edildi. Serebral vazospazmın teşhisi için, BPT'nin toplanmış duyarlılık, özgüllük, PLR, NLR, DOR, ve AUC değerleri sırasıyla %94; %90; 8,22; 0,06; 141,09 ve 0,9802 idi. BTP parametrelerinin değerlendirilmesi yoluyla MT için daha yüksek duyarlılık (%91) ve CBF için daha yüksek özgüllük saptandı (%93). soNuÇ: BTP testinin anevrizmal subaraknoid hemorajili (aSAK) hastalarda serebral vazospazmı belirlemede anjiyografiye kıyasla önemli diyagnostik değeri vardır. BTP parametreleri olan CBF ve MTT beyin parankimi perfüzyonunu kantitatif olarak değerlendirirler.

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Cite This Article

YOU, C., LİU, Y., SUN, H., ZHANG, H., MA, J. (2022). Evaluating the Diagnostic Accuracy of CT Perfusion in Patients with Cerebral Vasospasm After Aneurysm Rupture: A Meta-Analysis. Turkish Neurosurgery, Cilt: 24 - Sayı: 5, 757–762. https://ajindex.com/articles/654626

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References (1)

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