Journals / Turkish Neurosurgery / 2019 / Cilt: 29 - Sayı: 2

Effect of Surgery on the Long-Term Functional Outcome of Moyamoya Disease: A Meta-Analysis

Pages
171–179
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Sensitivity analyses were conducted to check the robustness of overalleffect.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:AIM: To summarize and calculate the accurate rate of good outcome and the prognosis, using a uniform definition of good outcome,evaluating the long-term effect of surgery.MATERIAL and METHODS: Through searching the relevant databases, we included eligible studies measuring outcomes withthe modified Rankin Scale (mRS), Glasgow Outcome Scale (GOS) and Kim’s category.
📊
Key Findings & Data:Single group rates were transformedand synthesized to yield the mean weighted probability.
💡
Conclusion & Impact:Sensitivity analyses were conducted to check the robustness of overalleffect.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

AIM: To summarize and calculate the accurate rate of good outcome and the prognosis, using a uniform definition of good outcome,evaluating the long-term effect of surgery.MATERIAL and METHODS: Through searching the relevant databases, we included eligible studies measuring outcomes withthe modified Rankin Scale (mRS), Glasgow Outcome Scale (GOS) and Kim’s category. Single group rates were transformedand synthesized to yield the mean weighted probability. Sensitivity analyses were conducted to check the robustness of overalleffect. Subgroup analyses were stratified by study type, population, age phase, presentation, surgical procedure and outcomemeasurement.RESULTS: The overall estimated rate of good outcome was 0.87 (95%CI, 0.84 0.90), with substantial heterogeneity. In the subgroupanalyses, the outcome measured with GOS led to the highest rate of 91%, while Kim’s category had the lowest rate of 82%. Thecombined bypass surgery group resulted in a higher good outcome rate of 0.92 (95%CI, 0.89 0.96) than the indirect bypass groupof 0.83% (95%CI, 0.78 0.88).CONCLUSION: Moyamoya disease after surgical treatment could achieve a good outcome rate of 87%. Kim’s category reflectedthe functional outcome better, resulting in a good outcome rate of 82%. The combined bypass surgery led to better outcomes thanindirect bypass.

🔖

Cite This Article

YAO, Z., YOU, C. (2019). Effect of Surgery on the Long-Term Functional Outcome of Moyamoya Disease: A Meta-Analysis. Turkish Neurosurgery, Cilt: 29 - Sayı: 2, 171–179. https://ajindex.com/articles/405280

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Bao XY, Duan L, Yang WZ, Li DS, Sun WJ, Zhang ZS, Zong R, Han C: Clinical features, surgical treatment, and long-term outcome in pediatric patients with moyamoya disease in China. Cerebrovasc Dis 39:75-81, 2015 2. Beijer U, Wolf A, Fazel S: Prevalence of tuberculosis, hepatitis C virus, and HIV in homeless people: A systematic review and meta-analysis. Lancet Infect Dis 12:859-870, 2012 3. Caldarelli M, Di Rocco C, Gaglini P: Surgical treatment of moyamoya disease in pediatric age. J Neurosurg Sci 45:83- 91, 2001 4. Cheung AH, Lam AK, Ho WW, Tsang CP, Tsang AC, Lee R, Lui WM, Leung GK: Surgical outcome for Moyamoya Disease: Clinical and perfusion computed tomography correlation. World Neurosurg 98:81-88, 2017 5. Cho A, Chae JH, Kim HM, Lim BC, Hwang H, Hwang YS, Phi JH, Kim SK, Wang KC, Cho BK, Kim KJ: Electroencephalography in pediatric moyamoya disease: Reappraisal of clinical value. Childs Nerv Syst 30:449-459, 2014 6. Cho HH, Cheon JE, Kim SK, Choi YH, Kim IO, Kim WS, Lee SM, You SK, Shin SM: Quantitative assessment of neovascularization after indirect bypass surgery: Colorcoded digital subtraction angiography in pediatric Moyamoya Disease. AJNR Am J Neuroradiol 37:932-938, 2016 7. Cho WS, Kim JE, Kim CH, Ban SP, Kang HS, Son YJ, Bang JS, Sohn CH, Paeng JC, Oh CW: Long-term outcomes after combined revascularization surgery in adult moyamoya disease. Stroke 45:3025-3031, 2014 8. Czabanka M, Boschi A, Acker G, Pena-Tapia P, Schubert GA, Schmiedek P, Vajkoczy P: Grading of moyamoya disease allows stratification for postoperative ischemia in bilateral revascularization surgery. Acta Neurochir (Wien) 158:1895- 1900, 2016 9. Darwish B, Besser M: Long term outcome in children with Moyamoya disease: Experience with 16 patients. J Clin Neurosci 12:873-877, 2005 10. Deng X, Gao F, Zhang D, Zhang Y, Wang R, Wang S, Cao Y, Zhao Y, Pan Y, Ye X, Liu X, Zhang Q, Wang J, Yang Z, Zhao M, Zhao J: Effects of different surgical modalities on the clinical outcome of patients with moyamoya disease: A prospective cohort study. J Neurosurg 2017 (Epub Ahead of Print) 11. Gonzalez NR, Dusick JR, Connolly M, Bounni F, Martin NA, Van de Wiele B, Liebeskind DS, Saver JL: Encephaloduroarteriosynangiosis for adult intracranial arterial steno-occlusive disease: Long-term single-center experience with 107 operations. J Neurosurg 123:654-661, 2015 12. Hishikawa T, Tokunaga K, Sugiu K, Date I: Long-term outcomes in adult patients with ischemic-type moyamoya disease involving posterio