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Journals / Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi / 2013 / Cilt: 24 - Sayı: 1

The predictive value of 6-12 hour and 24 hour bilirubin levels in determining significant hyperbilirubinemia among healthy term neonates

Sağlıklı term yenidoğanlarda ortaya çıkan belirgin hiperbilirubineminin tahmininde 6.,12. ve 24. saat bilirubin değerlerinin önemi

Elif ÜNVER KORĞALI
Nedim SAMANCI
Nevin CAMBAZ
Meliha AKSOY OKAN
Gamze ÖZGÜRHAN
Özgül YİĞİT
Asiye NUHOĞLU
Pages
32–36
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

A bilirubin level at the 6-12th hours higher than 3.9 mg/dl was found to be significant with a sensitiv- ity and specificity of 67.6% and 64.9%, respectively (p

📌 3 Key Takeaways

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Objective & Hypothesis:Background: The predictive value of 6-12th and 24th hour bilirubin levels in determining significant hyperbilirubinemia among healthy term neonates was evaluated in this study.Methods: Term, healthy neonates with hyperbilirubinemia were included.
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Key Findings & Data:Serum total bilirubin levels were determined at the postnatal 6-12th and at the 24th, 48th, 72nd and 96th hours.
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Conclusion & Impact:A bilirubin level at the 6-12th hours higher than 3.9 mg/dl was found to be significant with a sensitiv- ity and specificity of 67.6% and 64.9%, respectively (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Background: The predictive value of 6-12th and 24th hour bilirubin levels in determining significant hyperbilirubinemia among healthy term neonates was evaluated in this study.Methods: Term, healthy neonates with hyperbilirubinemia were included. Serum total bilirubin levels were determined at the postnatal 6-12th and at the 24th, 48th, 72nd and 96th hours. The predictive value of the 6-12th and 24th hour biliru- bin levels in determining significant hyperbilirubinemia was evaluated by ROC analysis.Results: Of the 276 neonates, 134 (48.5%) were males and 142 (51.5%) were females. Clinical jaundice was observed in 240 (86%) of them. Thirty seven (13.4%) developed significant hyperbilirubinemia. A bilirubin level at the 6-12th hours higher than 3.9 mg/dl was found to be significant with a sensitiv- ity and specificity of 67.6% and 64.9%, respectively (p

Özet

Amaç: Bu çalışmada, term bebeklerde 6-12. saat ve 24. saat-teki bilirübin değerlerinin oluşabilecek belirgin hiperbilirü-bineminin göstergesi olup olmadığı değerlendirildi.Gereç ve Yöntem: Çalışmaya sağlıklı, term hiperbilirübine-mi tanısı alan yenidoğanlar alındı. Serum total bilirubin öl-çümleri yaşamın ilk 6-12. saatleri arasında yapıldı. Takip edengünlerde 24, 48, 72 ve 96. saatlerde tekrarlandı. Olguların6-12. saatler arasındaki ve 24. saatteki bilirubin değerleriROC analizi ile belirgin hiperbilirubineminin göstergesi olupolmadığı açısından değerlendirildi.Bulgular: Çalışmada 134’ü (%48.5) erkek, 142’si (%51.5) kız 276 yenidoğan değerlendirildi. Klinik sarılık 240 (%86) olgu- da görüldü. Otuz yedi (%13.4) olguda belirgin hiperbilirubi- nemi gelişti. 6.-12. saatler arasındaki 3.9 mg/dl’nin üzerin- deki bilirubin değerleri %67.6 duyarlılık, %64.9 özgüllük ile (p

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Cite This Article

KORĞALI, E. Ü., SAMANCI, N., CAMBAZ, N., OKAN, M. A., ÖZGÜRHAN, G., YİĞİT, Ö., NUHOĞLU, A. (2022). The predictive value of 6-12 hour and 24 hour bilirubin levels in determining significant hyperbilirubinemia among healthy term neonates. Kartal Eğitim ve Araştırma Hastanesi Tıp Dergisi, Cilt: 24 - Sayı: 1, 32–36. https://ajindex.com/articles/652813

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