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Journals / Journal of Clinical and Analytical Medicine / 2015 / Cilt: 6 - Sayı: 3

Tekrarlayan düşükte endokrin ve endometrial faktörler: Üçüncü basamak bir hastane deneyimi

The role of endocrine and endometrial factors in cases of recurrent miscarriage: A tertiary center experience

Ahmet UYSAL
Cüneyt Eftal TANER
Emine COŞAR
Semih MUN
Pages
300–303
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Discussion: We conclude that recurrent abortionshave a complex etiology related to endocrinologic and endometrial factors.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: To investigate endocrinologic and endometrial factors in cases of recurrent abortions.
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Key Findings & Data:Results: In 8 (14%) of57 cases with recurrent abortions, there were low progesterone levels.
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Conclusion & Impact:Discussion: We conclude that recurrent abortionshave a complex etiology related to endocrinologic and endometrial factors.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: To investigate endocrinologic and endometrial factors in cases of recurrent abortions. Material and Method: In cases of recurrent abortions, clinicaland ultrasonographic features, genetic, anatomic and immunologic factors,hormonal profles and endometrial samplings were assessed. Chromosomalabnormalities and uterine anomalies were excluded. Results: In 8 (14%) of57 cases with recurrent abortions, there were low progesterone levels. In 1(1.75%) case there was a high androgen level. In 2 (3.5%) cases there washyperprolactinemia and in another 2 (3.5%) cases there were high insulinlevels. In 4 (7%) cases two scores of OGTT were high. In 51 cases whereendometrial sampling was performed, only one (1.75%) case had delayedendometrial development. Discussion: We conclude that recurrent abortionshave a complex etiology related to endocrinologic and endometrial factors.

Özet

Amaç: Tekrarlayan gebelik kayıplarında endometrial ve endokrin problemleriaraştırmak. Gereç ve Yöntem: Tekrarlayan gebelik kaybı olan hastalarda, klinik ve sonografik görünümler, genetik, immünolojik ve anatomik faktörler,hormon profilleri, endometrial örneklemler incelendi. Kromozom anormallikleri ve uterus anaomalileri çalışma kapsamı dışında tutuldu. Bulgular: Tekrarlayan gebelik kaybı olan 57 hastanın 8inde (14%) düşük progesteron seviyeleri bulundu. Bir hastada (1.75%) yüksek androjen seviyesi, 2 (3.5%) hastada prolaktin yüksekliği, 2 (3.5%) hastada insülin seviyelerinde yükseklik tespit edildi. Dört olguda (7%) oral glikoz tolerans testinin 2 parametresi yüksek bulundu. Endometrial örnekleme yapılan 51 olgunun sadece 1 tanesindegecikmiş endometrial gelişim görüldü. Tartışma: Tekrarlayan gebelik kaybının hem endokrin hem endometrial faktörleri de içeren kompleks bir etiyolojiye sahip olduğu düşünüldü.

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Cite This Article

UYSAL, A., TANER, C. E., COŞAR, E., MUN, S. (2022). Tekrarlayan düşükte endokrin ve endometrial faktörler: Üçüncü basamak bir hastane deneyimi. Journal of Clinical and Analytical Medicine, Cilt: 6 - Sayı: 3, 300–303. https://ajindex.com/articles/652340

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