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Journals / İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi / 2015 / Cilt: 22 - Sayı: 3

Propofol ve Desfluran Anestezisinin Koroner Arter By-pass Cerrahisi Sonrası Nötrofil/Lenfosit Oranı Üzerine Etkilerinin Karşılaştırılması

Comparison of the Effects of Propofol Anaesthesia and Desflurane Anaesthesia on Neutrophil/Lymphocyte Ratios After Coronary Artery Bypass Surgery

Fahri ADALI
Elif DOĞAN BAKI
Mustafa EMMİLER
Nilgün ÖZTÜRK KAVRUT
Evren TECER
Ali Sai KAVAKLI
Osman Tansel DARÇIN
Mustafa ALDEMİR
Pages
165–170
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Results: At the postoperative 12th decrease in lymphocyte counts in group P was significantly lower than in group D (1.23 ± 0.81, 0.92 ± 1.01, respectively, with a p value of

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Coronary artery bypass surgery with cardiopulmonary bypass can induce postoperative systemic leukocytic alterations including leukocytosis, neutrophilia, or lymphopenia.
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Key Findings & Data:Materials and Methods: Sixty patients scheduled for coronary artery bypass surgery were randomly assigned into two groups: group P (n=30), which were anaesthesised with propofol (intravenous anaesthesia) and group D, which were anaesthesised with desflurane (inhalational anesthesia).
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Conclusion & Impact:Results: At the postoperative 12th decrease in lymphocyte counts in group P was significantly lower than in group D (1.23 ± 0.81, 0.92 ± 1.01, respectively, with a p value of
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Coronary artery bypass surgery with cardiopulmonary bypass can induce postoperative systemic leukocytic alterations including leukocytosis, neutrophilia, or lymphopenia. The present study aims to compare the effects of propofol and desflurane anaesthesia on the leukocytic alterations including neutrophil-to-lymphocyte ratios after coronary artery bypass surgery. Materials and Methods: Sixty patients scheduled for coronary artery bypass surgery were randomly assigned into two groups: group P (n=30), which were anaesthesised with propofol (intravenous anaesthesia) and group D, which were anaesthesised with desflurane (inhalational anesthesia). Differential counts of leukocytes with neutrophil/lymphocyte ratios of peripheral blood were obtained just before anaesthesia induction (for basal values), at the postoperative 12th, 24th, and 48th hours. Results: At the postoperative 12th decrease in lymphocyte counts in group P was significantly lower than in group D (1.23 ± 0.81, 0.92 ± 1.01, respectively, with a p value of

Özet

Amaç: Kardiyopulmoner by-pass ile yapılan koroner arter by-pass cerrahisi lökositoz, nötrofili ve lenfopeniyi de içeren postoperatif lökosit dağılımı değişikliklerini başlatabilir. Bu çalışma ile kardiyopulmoner bypass kullanılarak koroner by-pass cerrahisine giden hastalarda propofol (intravenöz) ve desfluran (inhalasyon) anestezisinin postoperatif lökositik değişiklikler ve nötrofil/ lenfosit oranı üzerine etkileri incelenmiştir.Gereç ve Yöntemler: Bu prospektif randomize çalışmada elektif koroner arter by-pass cerrahisi planlanan 60 hasta iki eşit gruba randomize edildi. olgulardan 30'unda (grup P, n=30) propofol (intravenöz) anestezi ve diğer 30'unda ise (grup D, n=30) desfluran (inhalasyon anestezisi kullanıldı. Hastalardan lökosit alt tipleri ve nötrofil/lenfosit oranı tayini için anestezi indüksiyonundan hemen önce (bazal değer), postoperatif 12. saat, 24. saat ve 48. saatlerde olmak üzere periferik venden kan örneği alındı. Bulgular: Postoperatif 12.saat kan sayımlarında lenfosit sayısındaki düşüş grup P'de grup D'ye göre daha az belirgin (sırasıyla 1.23 ± 0.81, 0.92 ± 1.01 ve p değeri

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Cite This Article

ADALI, F., BAKI, E. D., EMMİLER, M., KAVRUT, N. Ö., TECER, E., KAVAKLI, A. S., DARÇIN, O. T., ALDEMİR, M. (2022). Propofol ve Desfluran Anestezisinin Koroner Arter By-pass Cerrahisi Sonrası Nötrofil/Lenfosit Oranı Üzerine Etkilerinin Karşılaştırılması. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, Cilt: 22 - Sayı: 3, 165–170. https://ajindex.com/articles/651943

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