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Journals / Hacettepe Dişhekimliği Fakültesi Derg.(. Clinical Dentistry and Research) / 2007 / Cilt: 31 - Sayı: 3

Role of growth factor on periodontal tissue healing

Periodontal dokuların iyileşmesinde büyüme faktörlerinin rolü

Atilla BERBEROĞLU
Pages
114–121
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The purpose of this review is to discuss the role of PDGF, TGF, FGF, IGF and EGF and their regulatory mechanisms of regenerative process in the periodontal tissues based on currently published studies.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Growth factors are biologically active polypeptide hormones, which have been shown to play a critical role in the stimulation and regulation of the periodontal regeneration and repair.
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Key Findings & Data:They express their action by binding to specific cell-surface receptors present on various target cells including osteoblasts, cementoblasts and periodontal ligament fibroblasts.
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Conclusion & Impact:The purpose of this review is to discuss the role of PDGF, TGF, FGF, IGF and EGF and their regulatory mechanisms of regenerative process in the periodontal tissues based on currently published studies.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Growth factors are biologically active polypeptide hormones, which have been shown to play a critical role in the stimulation and regulation of the periodontal regeneration and repair. They express their action by binding to specific cell-surface receptors present on various target cells including osteoblasts, cementoblasts and periodontal ligament fibroblasts. The purpose of this review is to discuss the role of PDGF, TGF, FGF, IGF and EGF and their regulatory mechanisms of regenerative process in the periodontal tissues based on currently published studies.

Özet

Biyolojik olarak aktif polipeptit hormonlar olanbüyüme faktörleri periodontal rejenerasyon ve tamirsırasında hücrelerin stimulasyonu ve regulasyonundaönemli bir rol oynarlar. Bu işlevlerini osteoblastlar,sementoblastlar ve periodontal ligament fibroblastlarıgibi çeşitli hedef hücrelerdeki özgün reseptörlerebağlanarak gerçekleştirirler. Bu derlemenin amacı;PDGF, TGF, FGF, IGF ve EGF leri ve regülasyonmekanizmalarını periodontal rejenerasyondakiişlevleri açısından yayınlanmış araştırmaların ışığındatartışmaktır.

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Cite This Article

BERBEROĞLU, A. (2022). Role of growth factor on periodontal tissue healing. Hacettepe Dişhekimliği Fakültesi Derg.(. Clinical Dentistry and Research), Cilt: 31 - Sayı: 3, 114–121. https://ajindex.com/articles/651186

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