AI Summary & Key Takeaways
AI InsightAlthough rare, there are acute-onset chronic inflammatory demyelinating polyneuropathy cases that show progression over a period shorter than 4 weeks, as is the case in Guillan-Barre Syndrome .This report discusses a case of chronic inflammatory demyelinating polyneuropathy in a HBsAg-positive patient, which started as Guillan-Barre Syndrome but showed 3 recurrences within 6 months, each with rapidly progressing quadriplegia, respiratory arrest, and elevated liver enzymes and HBV DNA
📌 3 Key Takeaways
Abstract
Chronic inflammatory demyelinating polyneuropathy is a demyelinating distal/proximal weakness, which shows gradual progression over a period of 8 weeks or longer. GuillanBarre Syndrome is a condition characterized by acute monophasic paralysis typically following an infectious assault, and it usually peaks in severity over 3-4 weeks at most. Although rare, there are acute-onset chronic inflammatory demyelinating polyneuropathy cases that show progression over a period shorter than 4 weeks, as is the case in Guillan-Barre Syndrome .This report discusses a case of chronic inflammatory demyelinating polyneuropathy in a HBsAg-positive patient, which started as Guillan-Barre Syndrome but showed 3 recurrences within 6 months, each with rapidly progressing quadriplegia, respiratory arrest, and elevated liver enzymes and HBV DNA
Özet
Kronik inflamatuar demiyelinizan polinöropati , 8 hafta ya da daha uzun süre içerisinde kademeli olarak ilerleyen, distal/proksimal kuvvetsizlik ile karakterize demiyelinizan bir polinöropati tablosudur. Guillan-Barre Sendromu ise sıklıkla enfeksiyon tablosu sonrası izlenen akut monofazik, en geç 3-4 haftada en üst düzey bulgulara ulaşan paralizi durumudur. Nadir de olsa Guillan-Barre Sendromu gibi 4 haftadan kısa süre içerisinde progresyon gösteren akut başlangıçlı kronik inflamatuar demiyelinizan polinöropati vakaları da mevcuttur. Burada HBsAg pozitif hastada,Guillan-Barre Sendromu gibi başlayan ancak 6 ay içerisinde 3 kez rekürrens gözlenen ve her rekürrens sırasında hızla ilerleyen quadripleji,solunum arresti gelişen ve karaciğer enzimlerinde ve HBV DNA' da yükseklik saptanan kronik inflamatuar demiyelinizan polinöropati olgusu sunulmuştur