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Journals / Viral Hepatitis Journal / 2018 / Cilt: 24 - Sayı: 1

Hepatitis B and C Sero-prevalence in Patients with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome at a Tertiary Care Hospital in Izmir

İzmir’de Üçüncü Basamak Bir Hastanede İnsan İmmün Yetmelik Virüsü/Edinsel Bağışıklık Yetmezliği Sendromu Olgularında Hepatit B ve C Sero-prevalansı

Ufuk SÖNMEZ
Sabri ATALAY
Tuba TATLI KIŞ
Şükran KÖSE
Pages
3–6
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Absence of anti-HCV positivity suggests that hepatitis Cinfection is not a major health problem in this population.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Infections caused by human immunodeficiency virus(HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) representa significant health problem.
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Key Findings & Data:Ourstudy was planned to investigate the prevalence of HBV and HCVinfections in HIV/Acquired Immune Deficiency syndrome (AIDS)patients followed up at our institution.Materials and Methods: In this study conducted in the Departmentof Infectious Diseases and Clinical Microbiology at Izmir TepecikTraining and Research Hospital, medical records of patients followedat the HIV/AIDS outpatient clinic between August 2002 andDecember 2014 were evaluated.
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Conclusion & Impact:Absence of anti-HCV positivity suggests that hepatitis Cinfection is not a major health problem in this population.
🔬Design:Research Article
📍Scope:2002 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: Infections caused by human immunodeficiency virus(HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) representa significant health problem. Co-infection with these viral agents isnot uncommon as a result of the similar transmission routes. Ourstudy was planned to investigate the prevalence of HBV and HCVinfections in HIV/Acquired Immune Deficiency syndrome (AIDS)patients followed up at our institution.Materials and Methods: In this study conducted in the Departmentof Infectious Diseases and Clinical Microbiology at Izmir TepecikTraining and Research Hospital, medical records of patients followedat the HIV/AIDS outpatient clinic between August 2002 andDecember 2014 were evaluated. Demographic data, main route ofHIV transmission, hepatitis B surface antigen (HBsAg), anti-hepatitisB core (HBc) immunoglobulin G (IgG), anti-HBs and anti-HCV resultswere evaluated.Results: A total of 157 treatment-naïve patients who were followedup at our HIV/AIDS outpatient clinic were included in this study.Four patients (2.6%), had HBsAg positivity. Anti-HBc IgG and antiHBspositivity were detected in 34% and 28.4% of the patients,respectively. No patients had anti-HCV positivity.Conclusion: The prevalence of HBsAg in HIV-positive individualswas found to be similar to that in other population-based studies inour country. Absence of anti-HCV positivity suggests that hepatitis Cinfection is not a major health problem in this population.

Özet

Amaç: İnsan immün yetmelik virüsü (HIV), hepatit B virüsü (HBV) ve hepatit C virüsünün (HCV) neden olduğu enfeksiyonlar önemli bir sağlık sorunudur. Bulaş yollarının benzerliği nedeni ile bu enfeksiyonların birlikteliği (ko-enfeksiyonu) nadir değildir. Çalışmamızda kliniğimizde HIV/Edinsel Bağışıklık Yetmezliği sendromu (AIDS) tanısı ile takip edilen hastalarda HBV ve HCV prevalansının incelenmesi amaçlanmıştır. Gereç ve Yöntemler: İzmir Tepecik Eğitim ve Araştırma Hastanesi’nde Ağustos 2002-Aralık 2014 tarihleri arasında HIV/AIDS tanısıyla takipli hastalar retrospektif olarak incelendi. Demografik özellikler, HIV’nin en olası geçiş yolu ve hepatit B yüzey antijeni (HBsAg), anti-hepatit B çekirdeği (HBc) immünoglobülin G (IgG), antiHBs ve anti-HCV sonuçları değerlendirildi. Bulgular: Bu çalışmaya, polikliniğimizde takip edilen 157 naiv HIV/AIDS hastası dahil edildi. Dört hastada (%2,6) HBsAg pozitifliği saptandı. Anti-HBc IgG ve anti-HBs pozitifliği sırasıyla %34 ve %28,4 saptanmış olup, hiç bir hastada anti-HCV pozitifliği saptanmamıştır. Sonuç: HIV pozitif kişilerde HBsAg sıklığı ülkemizde yapılmış popülasyon tabanlı diğer çalışmalar ile benzer oranda saptanmıştır. Anti-HCV pozitifliğinin olmaması, hepatit C enfeksiyonunun bu hasta grubunda önemli bir sağlık problemi olmadığını düşündürmektedir.

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Cite This Article

SÖNMEZ, U., ATALAY, S., KIŞ, T. T., KÖSE, Ş. (2022). Hepatitis B and C Sero-prevalence in Patients with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome at a Tertiary Care Hospital in Izmir. Viral Hepatitis Journal, Cilt: 24 - Sayı: 1, 3–6. https://ajindex.com/articles/646417

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