Journals / Viral Hepatitis Journal / 2021 / Cilt: 27 - Sayı: 3

Effect of a Nationwide Universal HBV Vaccination Program and Catch-up Vaccination Campaign on HBV Prevalence in Children

Ülke Çapında Evrensel HBV Aşılama Programının ve Yakalama Aşı Kampanyasının Çocuklarda HBV Prevalansı Üzerindeki Etkisi

Pages
148–152
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Of the overall study group, 2099 (49.3%) were male and 2157 (50.7%) were female.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: In infants vaccinated at birth against hepatitis B virus (HBV) in the context of a universal vaccination program, antibody titers may reduce over years, with a need for a booster dose at adolescence.
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Key Findings & Data:The aim of the study was to evaluate the immunity and carriage status 8-10 years after 3 doses of HBV vaccine administered in infancy.
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Conclusion & Impact:Of the overall study group, 2099 (49.3%) were male and 2157 (50.7%) were female.
🔬Design:Research Article
📍Scope:2008 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: In infants vaccinated at birth against hepatitis B virus (HBV) in the context of a universal vaccination program, antibody titers may reduce over years, with a need for a booster dose at adolescence. The aim of the study was to evaluate the immunity and carriage status 8-10 years after 3 doses of HBV vaccine administered in infancy. Materials and Methods: This was a descriptive, cross-sectional, community-based field study and was carried out between 2008 and 2011. Children with an anti-HBs titer ≤9 IU/mL, 10 to 99 IU/mL, and ≥100 IU/mL were categorized as negative, positive, and strongly positive. Results: A total of 4,256 students born between 1995 and 2004 (age range: 7-12 years) were included in the study. Of the overall study group, 2099 (49.3%) were male and 2157 (50.7%) were female. In 62.3% of the children in group A (born in or before 1999), anti-HBs titers were above the protection limit (≥10 IU/mL), while this rate was 37.3% in group B (born in or after 2000), with a statistically significant difference (p

Özet

Amaç: Evrensel bir aşılama programı bağlamında doğumda hepatit B virüse (HBV) karşı aşılanan bebeklerde yıllar içinde antikor titreleri azalabilir ve ergenlik döneminde bir takviye dozuna ihtiyaç duyulabilir. Çalışmanın amacı, bebeklik döneminde uygulanan 3 doz HBV aşısından 8-10 yıl sonra bağışıklık ve taşıyıcılık durumunu değerlendirmektir. Gereç ve Yöntemler: Bu tanımlayıcı, kesitsel, toplum temelli bir saha çalışmasıdır ve 2008 ile 2011 yılları arasında yapılmıştır. Anti-HBs titresi ≤9 IU/mL, 10 ila 99 IU/mL ve ≥100 IU/mL olan çocuklar negatif, pozitif ve güçlü pozitif olarak sınıflandırılmıştır. Bulgular: Araştırmaya 1995-2004 yılları arasında (yaş aralığı: 7-12 yıl) doğan toplam 4.256 öğrenci dahil edilmiştir. Genel çalışma grubunun 2099’u (%49,3) erkek ve 2157’si (%50,7) kadındı. Grup A’daki (1999 ve öncesi doğumlu) çocukların %62,3’ünde anti-HBs titreleri koruma sınırının üzerindeydi (≥10 IU/mL), grup B’de ise bu rakam (2000 ve sonrası doğumlu) istatistiksel olarak anlamlı bir farkla (p

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Cite This Article

TOSUN, S., KASIRGA, E., DEVECİ, S. (2022). Effect of a Nationwide Universal HBV Vaccination Program and Catch-up Vaccination Campaign on HBV Prevalence in Children. Viral Hepatitis Journal, Cilt: 27 - Sayı: 3, 148–152. https://ajindex.com/articles/646309

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