Journals / Viral Hepatitis Journal / 2021 / Cilt: 27 - Sayı: 2

Evaluation of HBsAg, Anti-HCV, Anti-HIV Seroprevalence and Perinatal Outcomes in Pregnant Women

Gebe Kadınlarda HBsAg, Anti-HCV, Anti-HIV Seroprevalansının ve Perinatal SonuçlarınDeğerlendirilmesi

Pages
103–108
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Seropositivity rates of pregnant women were investigated according to the results of hepatitis B surface antigen (HBsAg), HCV antibody and anti-HIV antibody.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Vertical transmission of hepatitis B virus, hepatitis C virus, (HBV, HCV) and human immunodeficiency viruses (HIV) infections is an important public health problem.
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Key Findings & Data:The aim of this study was to determine the rates of hepatitis B, anti-HCV and antiHIV seropositivities in pregnant women in a city and to evaluate the infections in terms of perinatal outcomes.
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Conclusion & Impact:Seropositivity rates of pregnant women were investigated according to the results of hepatitis B surface antigen (HBsAg), HCV antibody and anti-HIV antibody.
🔬Design:Research Article
📍Scope:2015 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: Vertical transmission of hepatitis B virus, hepatitis C virus, (HBV, HCV) and human immunodeficiency viruses (HIV) infections is an important public health problem. The aim of this study was to determine the rates of hepatitis B, anti-HCV and antiHIV seropositivities in pregnant women in a city and to evaluate the infections in terms of perinatal outcomes. Materials and Methods: In this retrospective study, 8,464 patients who gave birth in obstetrics and gynecology clinic were recorded. Seropositivity rates of pregnant women were investigated according to the results of hepatitis B surface antigen (HBsAg), HCV antibody and anti-HIV antibody. The rates were determined according to years and perinatal results and statistical comparison was made. Results: HBsAg seropositivity in pregnant women included in the study was 2.8 % (n=55) in 2015, 2.2% (n=52) in 2016, 2.3% (n=47) in 2017 and 2.2% (n=49) in 2018. The 4 year average was found to be 2.3% (n=203). There was no significant difference between the years (p>0.05). Among all our patients, 4-year mean anti-HCV seropositivity was 0.57% (n=49) and there was no difference between years (p>0.05). Anti-HIV seropositivity was found to be 0.09% on average, and there was no statistically significant difference over the years (p>0.05). Conclusion: Since hepatitis B, which is a preventable viral disease, has a risk of transmission during delivery and if it is transmitted to the fetus, it may lead to fatal complications at later ages, it is necessary to screen all pregnant women in terms of HBsAg seropositivity and to include it in an antepartum planning program to protect and treat newborns from infection. Although the transmission rate of HCV is low in the society, considering its clinical course, screening of HCV together with HIV in risky groups and pregnant women antibody positivity is considered important for the health of the society and newborns.

Özet

Amaç: Hepatit B virüsü, hepatitis C virüsü (HBV, HCV) ve insan immün yetmezlik virüsleri (HIV) enfeksiyonlarının dikey bulaşması önemli bir halk sağlığı problemidir. Bu çalışmadaki amaç bir ildeki gebelerde hepatit B, anti-HCV ve anti-HIV seropozitiflik oranlarını belirlemek ve enfeksiyonları perinatal sonuçlar açısından değerlendirmektir. Gereç ve Yöntemler: Bu retrospektif çalışmada kadın hastalıkları ve doğum kliniğinde doğumu gerçekleştirilmiş 8,464 hasta kayıt altına alınmıştır. Gebelerde seropozitiflik oranları, hepatit B yüzey antijeni (HBsAg), HCV antikoru ve tespit edilen anti-HIV antikoru sonuçlarına göre araştırıldı. Yıllara göre ve perinatal sonuçlara göre oranlar belirlenip istatistiki karşılaştırma yapıldı. Bulgular: Çalışmaya alınan gebelerde HBsAg seropozitifliği 2015 yılında %2,8 (n=55), 2016 yılında %2,2 (n=52), 2017 yılında %2,3 (n=47) ve 2018 yılında ise %2,2 (n=49) bulunmuş olup 4 yıllık ortalaması %2,3 (n=203) olarak hesaplanmıştır. Yıllar arasında anlamlı bir farklılık gözlenmemiştir (p>0,05). Tüm hastalarımız içinde dört yıllık ortalama anti-HCV seropozitifliği %0,57 (n=49) olup yıllar arasında fark bulunmadı (p>0,05). Anti-HIV seropozitifliği ortalama olarak %0,09 olarak saptanmış olup yıllara göre istatistiki anlamda bir farklılık izlenmemiştir (p>0,05). Sonuç: Önlenebilir bir viral hastalık olan hepatit B’nin doğum esnasında bulaş riski olduğundan ve fetusta bulaş olursa ilerleyen yaşlarda ölümcül komplikasyonlara yol açabileceğinden tüm gebelerin HBsAg seropozitifliği açısından taranması ve bunun bir antepartum planlama programına dahil edilmesi yenidoğanların enfeksiyondan korunması ve tedavi edilmesi için gereklidir. HCV’nin toplumda bulaş oranı düşük bir düzeyde olmasına karşın klinik seyri dikkate alındığında riskli gruplarda ve gebelerde HIV ile birlikte taranması toplum ve yenidoğan bebeklerin sağlığı için önemli görülmektedir.

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Cite This Article

ÇAĞLAYAN, İ., UÇKAN, T., UÇKAN, K. (2022). Evaluation of HBsAg, Anti-HCV, Anti-HIV Seroprevalence and Perinatal Outcomes in Pregnant Women. Viral Hepatitis Journal, Cilt: 27 - Sayı: 2, 103–108. https://ajindex.com/articles/646302

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