Journals / Türk Plastik Rekonstrüktif ve Estetik Cerrahi Derg. / 2005 / Cilt: 13 - Sayı: 1

Desmoplastic malignant melanoma: An entity that must differatiate from dermatofibroma and Spitz nevus

Spitz nevüs ve dermatofibromdan ayrılması gereken bir tanı: Desmoplastik malign melanom

Pages
53–56
Publication Date
2022-11-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Clinical information, histological and immunohistochemical findings are guides for the final diagnosis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Desmoplastic malignant melanoma (DMM) is an uncommon variant of malignant melanoma.
📊
Key Findings & Data:We present a case of 44-years-old man with DMM on his right leg.
💡
Conclusion & Impact:Clinical information, histological and immunohistochemical findings are guides for the final diagnosis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Desmoplastic malignant melanoma (DMM) is an uncommon variant of malignant melanoma. DMM has clinical and histological features that may be subtle and misdiagnosed as benign or malignant skin lesions that would require less aggressive therapy. We present a case of 44-years-old man with DMM on his right leg. The histological and immunohistochemical findings of the examination of specimen were consistent with DMM. The diagnosis of DMM should always be considered whenever a lesion composed of pleomorphic spindle cells with stromal desmoplasia. Clinical information, histological and immunohistochemical findings are guides for the final diagnosis.

Özet

Desmoplastik malign melanom (DMM), malign melanomun nadir görülen bir histolojik alt tipidir. DMM’un tedavisi daha az agresif olabilen diğer iyi huylu ve kötü huylu deri lezyonlar ile ayrlması zor klinik ve histolojik özellikleri mevcuttur. Bu çalışmada 44 yaşında sağ bacağında DMM olan bir olgu sunulmuştur. Spesimenin histolojik ve immünohistokimyasal özellikleri DMM ile uyumlu olarak bulunmuştur. DMM tanısı; histolojik incelenmede, lezyonda pleomorfik iğsi hücreler ve stromal desmoplazi mevcut ise mutlaka akla getirilmelidir. Son tanıya götürmede klinik bilgiler, histolojik ve immünohistokimyasal bulgular yardımcıdır

🔖

Cite This Article

BENLİER, E., KARAMAN, D., TOP, H. (2022). Desmoplastic malignant melanoma: An entity that must differatiate from dermatofibroma and Spitz nevus. Türk Plastik Rekonstrüktif ve Estetik Cerrahi Derg., Cilt: 13 - Sayı: 1, 53–56. https://ajindex.com/articles/641822

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (9)

  1. Conley J, Lattes R, Orr W. Desmoplastic malignant melanoma (A rare variant of spindle-cell melanoma) Cancer 1971; 28: 914-936
  2. Beenken S, Byers R, Smith JL et al. Desmoplastic melanoma. Arch Otolaryngol Head Neck Surg 1989; 115: 374-379
  3. Anstey A, McKee P, Jones EW Desmoplastic malignant melanoma: A clinicopathological study of 25 cases. Br J Dermatol 1993; 129:359-371
  4. Payne WG, Kearney R, Wells K et al. Desmoplastic melanoma. Am Surg 2001; 67(10): 1004-1006
  5. Kaneishi NK, Cockerell CJ Histological differentiation of desmoplastic melanoma from cicatrices. Am J Dermathopathol 1998; 20: 128-134
  6. Chan GSW, Choy C, Ng WK, Chan KW. Desmoplastic malignant melanoma on the buttock of an 18-year-old girl. Am J Dermatopathol 1999; 21(2): 170-173
  7. Harris GR, Shea CR, Horenstein MG et al. Desmoplastic (Sclerotic) nevus. An underrecognized entity that resembles dermatofibroma and desmoplastic melanoma. Am J Surg Pathol 1999; 23(7): 786-794
  8. Payne WG, Kearney R, Wells K et al. Desmoplastic Melanoma. Am Surg 2001; 67(10): 104-106
  9. Wharton JM, Carlson JA, Mihm MC. Desmoplastic malignant melanoma: Diagnosis of early clinical lesions. Hum Pathol 1999; 30(5): 537-542.