Journals / Türk Plastik Rekonstrüktif ve Estetik Cerrahi Derg. / 2007 / Cilt: 15 - Sayı: 2

Giant basal cell carcinomas: The analysis of 12 patients

Dev bazal hücreli karsinomlar: 12 olgunun analizi

Pages
73–78
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The follow-up period isapproximately 3 years. ın this study the problems of giantbasal cell carcinoma such as the importance of the sitelocation in tumour development, the histologic subtypesinvolved and problems of treatment are discussed.

📌 3 Key Takeaways

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Objective & Hypothesis:Basal cell carcinomas are the most common cutaneousmalignant neoplasms.
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Key Findings & Data:Our study includes 12 patientswho had giant basal cellcarcinoma with no evidence of metastatic dissemination.Three lesions on the scalp, five lesions on the face, threelesions on the trunk and one lesion on the toraco-lomberregion were diagnosed.
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Conclusion & Impact:The follow-up period isapproximately 3 years. ın this study the problems of giantbasal cell carcinoma such as the importance of the sitelocation in tumour development, the histologic subtypesinvolved and problems of treatment are discussed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Basal cell carcinomas are the most common cutaneousmalignant neoplasms. Although frequently regarded as alow grade malignancy, basal cell carcinoma sometimesshows very aggressive behaviour, especially, where giantlesions are concerned.Giant basal cell carcinoma is a rareskin tumour with aggressive biological behaviour, and muchconfusions exists about their possible aggressive potential asrelated to their size, the risk factors their development, theirmanagement, and their recurrence after the treatment. Our study includes 12 patientswho had giant basal cellcarcinoma with no evidence of metastatic dissemination.Three lesions on the scalp, five lesions on the face, threelesions on the trunk and one lesion on the toraco-lomberregion were diagnosed. Except one case, all patientswere treated with surgically. Depending on the anatomicregion and tumour size, we usedlocal or distant flapsand skin grafts for the reconstruction of the defect after thewide excision of the carcinoma. The follow-up period isapproximately 3 years. ın this study the problems of giantbasal cell carcinoma such as the importance of the sitelocation in tumour development, the histologic subtypesinvolved and problems of treatment are discussed.

Özet

Bazal hücreli kanserler derinin en sık görülen kanserleridir. Bu tür kanserler sıklıkla düşük dereceli malignite gösterseler de, özellikle büyük boyutlar söz konusu olduğunda daha saldırgan bir karakter gösterebilmektedirler. Dev bazal hücreli kanserler nadir görülmekle birlikte daha kötü klinik seyre sahip oldukları bilinse de, boyutlara bağlı tümörün seyri, gelişimlerindeki risk faktörleri, yaklaşım ve tedavi sonrası nüks etmeleri gibi birçok konu henüz tam olarak aydınlanmamıştır. Çalışmamız metastatik yayılımı olmayan 12 dev bazal hücreli kanserli hastadan oluşmaktadır. Lezyonlardan üçü skalpte, beş adedi yüzde, ikisi toraksta ve bir tanesi torako-lomber bölgelerde teşhis edildi. Bir olgu dışında tüm olgularda cerrahi tedavi uygulandı. Kanserlerde geniş rezeksiyonlardan sonra rekonstrüksiyon için anatomik bölgeye ve tümör boyutlarına bağlı olarak lokal veya uzak flepler ve deri greftleri kullanıldı. Hastalarda takip süresi yaklaşık 3 yıl olarak gerçekleşti. Çalışmamızda dev bazal hücreli kanserlerde lokalizasyonun tümör gelişiminde önemi, histolojik tipler ve tedavide karşılaşılan problemler gibi bazı tartışmalı konular ele alındı.

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Cite This Article

AKAN, M., KARANFİL, H., MISIRLIOĞLU, A., AKÖZ, T. (2022). Giant basal cell carcinomas: The analysis of 12 patients. Türk Plastik Rekonstrüktif ve Estetik Cerrahi Derg., Cilt: 15 - Sayı: 2, 73–78. https://ajindex.com/articles/641804

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