Mediastinal granülositik sarkom

Objective & Hypothesis:Granulocytic sarcoma is an unusual variant of myeloid malignancy in which there is an extramedullary tumor mass composed of myeloblasts or myeloblasts and more mature neutrophils.

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Key Findings & Data:It rarely occurs in mediastinum and clinically may resemble a mediastinal lymphoma.

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Conclusion & Impact:The diagnosis of granulocytic sarcoma is not difficult with careful histopathologic evaluation and immunohistochemical staining.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Granulocytic sarcoma is an unusual variant of myeloid malignancy in which there is an extramedullary tumor mass composed of myeloblasts or myeloblasts and more mature neutrophils. It rarely occurs in mediastinum and clinically may resemble a mediastinal lymphoma. We report a patient who was initially diagnosed as malignant lymphoma based on the previous biopsy specimen. The diagnosis of granulocytic sarcoma is not difficult with careful histopathologic evaluation and immunohistochemical staining.

Özet

Granülositik sarkom miyeloblast veya daha matür nötrofillerden oluşan miyeloid malignitelerin nadir bir varyantı dır. Mediastende nadiren gelişir ve kliniği lenfomaya benzeyebilir. Bu makalede önceki biyopsi materyalinde lenfoma tanısı almış bir hasta rapor edilmektedir. Granülositik sarkom tanısı dikkatli histopatolojik ve immünhistokimyasal yöntemle zor değildir.

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Cite This Article

KARADOĞAN, İ., BEKÖZ, H., ÖZEL, E., AKKAYA, B., KARPUZOĞLU, G. (2022). Mediastinal granülositik sarkom. Türk Patoloji Dergisi, Cilt: 24 - Sayı: 3, 183–185. https://ajindex.com/articles/640864

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