Journals / Türk Patoloji Dergisi / 2022 / Cilt: 38 - Sayı: 2

GLUT-1 Expression in Breast Cancer

Pages
114–121
Publication Date
2022-11-06
DOI
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Results: GLUT-1 expression was correlated with poor prognostic factors such as estrogen receptor and progesterone receptor negativity, high Ki-67 proliferation index, and high histological and nuclear grade (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Numerous studies have been conducted to predict the prognosis of breast cancers.
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Key Findings & Data:The effect of glucose transporter protein 1 (GLUT-1), the main carrier protein responsible for glucose transport, was investigated in breast cancer patients.
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Conclusion & Impact:Results: GLUT-1 expression was correlated with poor prognostic factors such as estrogen receptor and progesterone receptor negativity, high Ki-67 proliferation index, and high histological and nuclear grade (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Numerous studies have been conducted to predict the prognosis of breast cancers. The effect of glucose transporter protein 1 (GLUT-1), the main carrier protein responsible for glucose transport, was investigated in breast cancer patients. Material and Method: 170 patients operated for breast carcinoma were included in this study. We analysed the prognostic significance of GLUT-1 immune-expression in 149 patients without neoadjuvant therapy, and in 21 patients with neoadjuvant therapy. Results: GLUT-1 expression was correlated with poor prognostic factors such as estrogen receptor and progesterone receptor negativity, high Ki-67 proliferation index, and high histological and nuclear grade (p

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Cite This Article

ŞEN, B., BEDİR, R., GÜVENDİ, G. F., OKÇU, O., ÖZTÜRK, Ç. (2022). GLUT-1 Expression in Breast Cancer. Türk Patoloji Dergisi, Cilt: 38 - Sayı: 2, 114–121. https://ajindex.com/articles/640341

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