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Journals / Türk Otorinolarengoloji Arşivi / 2016 / Cilt: 54 - Sayı: 2

Histopathological Effects of Fibrin Glue and Cyanoacrylate on the Maxillary Sinus

Fibrin Glue ve Siyanoakrilatın Maksiller Sinüs İçerisindeki Histopatolojik Etkileri

Sibel BEKTAŞ
Murat DAMAR
Erdal SAKALLI
Mehmet Birol UĞUR
Sultan BİŞKİN
Selda SARIKAYA
Pages
63–68
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: The FbGl group differed significantly from the CyAc and control groups in terms of a high degree of inflammation (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To compare the histopathological effects of fibrin glue (FbGl) and cyanoacrylate (CyAc) on the maxillary sinus mucosa.
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Key Findings & Data:Methods: Twenty rabbits were divided into two groups of 10, and surgical defects were created in the maxillary sinuses.
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Conclusion & Impact:Results: The FbGl group differed significantly from the CyAc and control groups in terms of a high degree of inflammation (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To compare the histopathological effects of fibrin glue (FbGl) and cyanoacrylate (CyAc) on the maxillary sinus mucosa. Methods: Twenty rabbits were divided into two groups of 10, and surgical defects were created in the maxillary sinuses. The right maxillary sinus was treated with FbGl in one group and with CyAc in the other group. As a control, the left maxillary sinuses of all rabbits were treated with sterile saline solution. One rabbit treated with CyAc died during the study and was excluded. On postoperative day 21, all animals were sacrificed. Maxillary sinus mucosa samples were studied to determine the extent of inflammation and fibrosis, foreign body reaction, cilia loss, increased osteogenesis in bony structures under the mucosa, and loss of serous glands. Results: The FbGl group differed significantly from the CyAc and control groups in terms of a high degree of inflammation (p

Özet

Amaç: Fibrin glue (FbGl) ve siyanoakrilatın (CyAc) maksiller sinüs mukozası üzerine histopatolojik etkilerini karşılaştırmak. Yöntemler: Çalışmaya 20 adet tavşan alındı ve her biri 10 adet olan iki gruba ayrıldı. Her iki grubun sağ maksiller sinüslerinde oluşturulan cerrahi defektleri birinci grupta (Grup 1) FbGl kullanılarak ikinci grupta (Grup 2) ise CyAc kullanılarak tedavi edildi. Her iki grubun sol maksiller sinüsleri steril salin solüsyonu ile tedavi edilerek kontrol grubu (Grup 3) olarak kullanıldı. Siyanoakrilat uygulanan ve çalışma sırasında ölen bir tavşan çalışma dışında bırakıldı. Postoperatif 21. gün bütün tavşanlar sakrifiye edildi. Her üç grubun maksiller sinus mukozasında histopatolojik olarak inflamasyon ve fibrozis yaygınlığı, yabancı cisim reaksiyonu, silia kaybı, mukoza altındaki kemikte osteogenezis artışı ve seröz gland kaybı oranları değerlendirildi. Bulgular: Her üç grup karşılaştırıldığında Grup 1(FbGl) istatistiksel olarak diğer iki gruptan daha yüksek oranda anlamlı inflamasyona (p

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Cite This Article

BEKTAŞ, S., DAMAR, M., SAKALLI, E., UĞUR, M. B., BİŞKİN, S., SARIKAYA, S. (2022). Histopathological Effects of Fibrin Glue and Cyanoacrylate on the Maxillary Sinus. Türk Otorinolarengoloji Arşivi, Cilt: 54 - Sayı: 2, 63–68. https://ajindex.com/articles/640272

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