Journals / Türk Otorinolarengoloji Arşivi / 2017 / Cilt: 55 - Sayı: 1

Analysis of Recurrence after Frontolateral Laryngectomy

Frontolateral Larenjektomi Sonrası Rekürens Analizi

Pages
27–30
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Frontolateral laryngectomy is an efficient choice of treatment for selected cases of T1 and T2 glottic laryngeal carcinoma

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: This study aimed to evaluate the recurrence and survival of patients treated with frontolateral laryngectomy for T1 and T2 glottic laryngeal carcinoma.
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Key Findings & Data:Methods: Patients who underwent frontolateral laryngectomy for glottic laryngeal carcinoma at a tertiary hospital between March 2009 and June 2014 were included.
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Conclusion & Impact:Conclusion: Frontolateral laryngectomy is an efficient choice of treatment for selected cases of T1 and T2 glottic laryngeal carcinoma
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: This study aimed to evaluate the recurrence and survival of patients treated with frontolateral laryngectomy for T1 and T2 glottic laryngeal carcinoma. Methods: Patients who underwent frontolateral laryngectomy for glottic laryngeal carcinoma at a tertiary hospital between March 2009 and June 2014 were included. Patient demographics, tumor stage, treatment and histopathological examination data, and adjuvant therapy details were evaluated. Results: Thirty patients with T1aN0, T1bN0, and T2N0 vocal fold carcinoma were examined. The mean follow-up duration was 40 months. Of the 30 patients, nine (30%) were stage T1 and 21 (70%) were in stage T2. Twenty-nine patients were males and one was female, and the mean age was 59 (range, 42-81) years. During follow-up, local recurrence was observed in four patients following frontolateral laryngectomy. Six patients continued smoking after frontolateral laryngectomy, of which three developed tumor recurrence. The local control rate was poor in patients with anterior commissure involvement (66.6%) compared with those with no involvement (95.2%). Two of four patients with local recurrence were treated with salvage total laryngectomy and adjuvant postoperative radiotherapy; the remaining two were treated with only radiotherapy. One patient who was treated with only radiotherapy developed lung metastasis during follow-up and died because of distant metastasis. Conclusion: Frontolateral laryngectomy is an efficient choice of treatment for selected cases of T1 and T2 glottic laryngeal carcinoma

Özet

Amaç: Bu çalışmada frontolateral larenjektomi ile tedavi edilen T1 ve T2 glottik kanserli hastalarda rekü- rens ve sağkalımın değerlendirilmesi amaçlandı. Yöntemler: Glottik larenks karsinomu nedeniyle Mart 2009 ve Haziran 2014 tarihleri arasında üçüncü basamak hastanede frontolateral larenjektomi uygulanan hastalar çalışmaya dahil edildi. Hastaların demografik özellikleri, tümör evreleri, tedavi ve histopatolojik inceleme verileri ile ek tedavi detayları değerlendirildi. Bulgular: Çalışmada, T1aN0, T1bN0 ve T2N0 glottik karsinomlu 30 hastanın verileri kaydedildi. Ortalama izlem süresi 40 aydı. Toplam 30 hastanın dokuzu (30%) T1, kalan 21'i (70%) T2 evresindeydi. Hastaların yirmi dokuzu erkek, biri kadındı ve ortalama yaş 59 (41-81) idi. Frontolateral larenjektomi sonrası izlemde dört hastada lokal rekürens gözlendi. Frontolateral larenjektomi sonrası altı hasta sigara içmeye devam etti ve bunların üçünde tümör rekürensi gelişti. Ön komissür tutulumu olan hastalarda lokal kontrol oranı (%66.6) olmayanlara göre (%95.2) daha kötü olarak saptandı. Rekürens geli- şen dört hastadan ikisine kurtarma total larenjektomisi ve postoperatif ek radyoterapi uygulandı; diğer iki hastaya ise sadece radyoterapi uygulandı. Yalnız radyoterapi ile tedavi edilen bir hastanın izleminde akciğer metastazı gelişti ve hasta uzak metastaz nedeniyle kaybedildi. Sonuç: Frontolateral larenjektomi seçilmiş T1 ve T2 glottik larenks karsinomlarında etkin bir tedavi seçeneğidir.

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Cite This Article

İMRE, A., SONGU, M., ÖNAL, K., ÖZKUL, Y., ATEŞ, D., BALCI, K., BAYRAK, F. (2022). Analysis of Recurrence after Frontolateral Laryngectomy. Türk Otorinolarengoloji Arşivi, Cilt: 55 - Sayı: 1, 27–30. https://ajindex.com/articles/640218

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