Journals / Türk Otorinolarengoloji Arşivi / 2018 / Cilt: 56 - Sayı: 2

The Effectiveness of Botulinum Toxin Type A Injections in the Management of Sialorrhea

Pages
111–113
Publication Date
2022-11-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Therewere no complications after the procedure.Conclusion: Botulinum toxin A injected in the majorsalivary glands in pediatric patients with neurologicaldisorders is a safe and effective method.Keywords: Sialorrhea, botulinum toxin, parotid gland,submandibular gland, cerebral palsy

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The aim of this study was to evaluate theeffect of Botulinum toxin type A by injecting in thesubmandibular and parotid glands on the frequencyand severity of sialorrhea.Methods: Pediatric patients who were referred to ourdepartment with sialorrhea were evaluated using theirparents’ frequency and severity scores of sialorrheawith visual analog scales before and after 3 months ofbotulinum toxin type A injections.
📊
Key Findings & Data:Seventeen patientswere female and 10 were male.
💡
Conclusion & Impact:Therewere no complications after the procedure.Conclusion: Botulinum toxin A injected in the majorsalivary glands in pediatric patients with neurologicaldisorders is a safe and effective method.Keywords: Sialorrhea, botulinum toxin, parotid gland,submandibular gland, cerebral palsy
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The aim of this study was to evaluate theeffect of Botulinum toxin type A by injecting in thesubmandibular and parotid glands on the frequencyand severity of sialorrhea.Methods: Pediatric patients who were referred to ourdepartment with sialorrhea were evaluated using theirparents’ frequency and severity scores of sialorrheawith visual analog scales before and after 3 months ofbotulinum toxin type A injections. Bilateral submandibular and parotid glands were injected with Botulinum toxin type A.Results: Twenty-seven pediatric patients who werereferred to our department with a complaint of sialorrhea were included in this study. Seventeen patientswere female and 10 were male. Severe sialorrhea withcerebral palsy was present in all the patients. Therewere no complications after the procedure.Conclusion: Botulinum toxin A injected in the majorsalivary glands in pediatric patients with neurologicaldisorders is a safe and effective method.Keywords: Sialorrhea, botulinum toxin, parotid gland,submandibular gland, cerebral palsy

🔖

Cite This Article

DAĞKIRAN, M., TARKAN, Ö., SÜRMELİOĞLU, Ö., KIROĞLU, M., ÖZDEMİR, S., ÇETİK, F., TUNCER, Ü. (2022). The Effectiveness of Botulinum Toxin Type A Injections in the Management of Sialorrhea. Türk Otorinolarengoloji Arşivi, Cilt: 56 - Sayı: 2, 111–113. https://ajindex.com/articles/640177

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (2)

  1. Garnock-Jones KP. Glycopyrrolate oral solution: for chronic, severe drooling in pediatric patients with neurologic conditions. Paediatr Drugs 2012; 14: 263-9. [CrossRef ] Hamdy S, Aziz Q, Rothwell JC, Hobson A, Barlow J, Thompson DG. Cranial nerve modulation of human cortical swallowing motor pathways. Am J Physiol 1997; 272: 802-8. [CrossRef ] Johnson, H., Scott, A. Saliva Management. In Dysphagia: Foundation, Theory and Practice; Cichero, J.A.Y., Murdoch, B.E., Eds.; John Wiley & Sons Ltd: West Sussex, UK, 2006; 126-9. Volonté MA, Porta M, Comi G. Clinical assessment of dysphagia in early phases of Parkinson's disease. Neurol Sci 2002; 23: 121-2. [CrossRef ] Glickman S, Deaney CN. Treatment of relative sialorrhoea with botulinum toxin type A: description and rationale for an injection procedure with case report. Eur J Neurol 2001; 8: 567-71. [CrossRef ] Hung CC, Fu PK, Wang HY, Chan CH, Lan TH. Treatment effects of traditional Chinese medicines Suoquan Pill and Wuling Powder on clozapine-induced hypersalivation in patients with schizophrenia: study protocol of a randomized, placebo-controlled trial. Zhong Xi Yi Jie He Xue Bao 2011; 9: 495-502. [CrossRef ] Scully C, Limeres J, Gleeson M, Tomás I, Diz P. Drooling. J Oral Pathol Med 2009; 38: 321-7. [CrossRef ] Holsinger, FC, Bui DT. Anatomy, function and evaluation of the salivary glands. Myers EN, Ferris RL, editors. Salivary Gland Disorders. Berlin, Heidelberg: Springer; 2007. p.1–16.
  2. Lin YC, Shieh JY, Cheng ML, Yang PY. Botulinum toxin type a for control of drooling in Asian patients with cerebral palsy. Neurology 2008; 70: 316-8. [CrossRef ] Fairhurst CB, Cockerill H. Management of drooling in children. Arch Dis Child Educ Pract Ed 2011; 96: 25-30. [CrossRef ] Pal PK, Calne DB, Calne S, Tsui JK. Botulinum toxin A as treatment for drooling saliva in PD. Neurology 2000; 54: 244-7. [CrossRef ] Wilken B, Aslami B, Backes H. Successful treatment of drooling in children with neurological disorders with botulinum toxin A or B. Neuropediatrics 2008; 39: 200-4. [CrossRef ] Meece RW, Fishlock KF, Bayley EW, Keller MS. Ultrasound-guided Botox injections of salivary glands in children with drooling. J Radiol Nurs 2010; 29: 20-4. [CrossRef ] Hassin-Baer S, Scheuer E, Buchman AS, Jacobson I, Ben-Zeev B. Botulinum toxin injections for children with excessive drooling. J Child Neurol 2005; 20: 120-3. [CrossRef ] Marina MB, Sani A, Hamzaini AH, Hamidon BB. Ultrasound-guided botulinum toxin A injection: an alternative t