Journals / Türk Otolarengoloji Arşivi / 2001 / Cilt: 39 - Sayı: 3

Rinoplasti sonrasında oluşan ödem ve ekimoza steroidlerin etkileri

Effects of steroids on edema and ecchymosis in rhinoplasty

Pages
171–175
Publication Date
2022-11-04
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

No complications were attributed to the administration of dexamethasone.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A randomized, prospective double-blind study with placebo control was planned to determine the effects of a single-dose dexamethasone in reducing postoperative edema and ecchymosis after rhinoplasty.
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Key Findings & Data:Thirty patients received 10 mg of dexamethasone intravenously before surgery and twenty-six patients received placebo.
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Conclusion & Impact:No complications were attributed to the administration of dexamethasone.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A randomized, prospective double-blind study with placebo control was planned to determine the effects of a single-dose dexamethasone in reducing postoperative edema and ecchymosis after rhinoplasty. Fifty-six consecutive patients who underwent rhinoplasty with hump removal and lateral osteotomies were enrolled in this study. Thirty patients received 10 mg of dexamethasone intravenously before surgery and twenty-six patients received placebo. Postoperative scoring of edema and ecchymosis was begun approximately 24 hours after surgery. All patients were operated by the authors. A 4-point scale was used to assess the extent of periorbital edema and ecchymosis 24 hours postoperatively. A single-dose of 10 mg of dexamethasone intravenously redu-ced postoperative edema and ecchymosis significantly. The first two days differences between the steroid and placebo groups for edema and ecchymosis were clinically and statisti-cally significant (p < 0.05). This study showed a statistically significant benefit of Steroids when compared to placebo in decreasing edema and ecchymosis in rhinoplasty. However, the effect of dexamethasone has disappeared after the first two days, and its use did not shorten the recovery. No complications were attributed to the administration of dexamethasone.

Özet

Rinoplasti sonrasında oluşan postoperatif ödem ve ekimozu azaltmada tek doz deksametazonun etkinliğini belirlemek için plasebo kontrollü prospektif bir randomize, çift kör çalışma planlandı. Hump rezeksiyonu ve lateral osteotomi uygulanan elli altı hasta çalışmaya dahil edildi. Otuz hastaya cerrahiden önce 10 mg intravenöz deksametazon, yirmi altı hastaya plasebo verildi. Postoperatif ödem ve ekimozun skorlaması yaklaşık olarak operasyondan 24 saat sonra başladı. Tüm hastalar yazarlar tarafından opere edildi. 24 saat sonraki periorbital ödem ve ekimozun şiddetini değerlendirmek için 4 puanlık bir skala kullanıldı. intravenöz olarak uygulanan 10 mg deksametazonun postoperatif ödem ve ekimozu anlamlı derecede azalttığı gözlendi. Steroid ve plasebo grupları arasında, ilk iki gündeki ödem ve ekimoz arasındaki farklar klinik ve istatistiksel olarak anlamlı bulundu (p

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Cite This Article

ERİŞİR, F., ÖKTEM, F., İNCİ, E. (2022). Rinoplasti sonrasında oluşan ödem ve ekimoza steroidlerin etkileri. Türk Otolarengoloji Arşivi, Cilt: 39 - Sayı: 3, 171–175. https://ajindex.com/articles/640127

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References (15)

  1. Stucker F J. Prevention of post-rhinoplasty edema. Laryngoscope 1974; 84(4): 536-41
  2. Kara CO, Gökalan I. Effects of single-dose steroid usage on ede- ma, ecchymosis, and intraoperative bleeding in rhinoplasty. Plast Reconstr Surg 1999; 104(7): 2213-8
  3. Schmidt JH, Caffee HH. The efficacy of methylprednisolone in re- ducing flap edema. Plast Reconstr Surg 1990; 86(6): 1148-51
  4. Habal MB, Powell RD. Experimental facial edema: Treatment with methylprednisolone. J Surg Res 1978; 24(5): 353-8
  5. Schaberg SJ, Stuller CB, Edwards SM. Effects of methylpredniso- lone on swelling after orthognatic surgery. J Oral Maxillofac Surg 1984; 42(6): 356-61
  6. Echavez MI, Mangat DS. Effects of steroids on mood, edema, and ecchymosis in facial plastic surgery. Arch Otolaryngol Head Neck Surg 1994; 120(10): 1137-41
  7. Beirne OR, Hollander B. The effect of methylprednisolone on pa- in, trismus and swelling after removal of third molars. Oral Surg Oral Med Oral Pathol 1986; 61(2): 134-8
  8. Pedersen A. Decadronphosphate in the relief of complaints after third molar surgery. A double-blind controlled trial with bilateral oral surgery. Int J Oral Surg 1985; 14(3): 235-40
  9. Sisk AL, Bonnington GJ. Evaluation of methylprednisolone and flurbiprofen for inhibition of postoperative inflammatory response. Oral Surg Oral Med Oral Pathol 1985; 60(2):137-45
  10. Gillman AF, Rall TW. Goodman and Gilman’s. The Pharmacolo- gical Basis of Therapeutics. 8th Ed. New York, NY, Pergamon 1990; 1442
  11. Haynes RC, Larner J. Adrenocorticotropic hormone, adrenocorti- cal steroids and their synthetic analogs: Inhibitors of adrenocortical steroids biosynthesis. In: The Pharmacological Basis of Therape- utics. Goodman LS, Gillman, A (Eds.). 5th Ed. New York, Macmil- lan Publishing Co., 1975; 1472
  12. Katzung BG. Basic and Clinical Pharmacology. California, Lange Medical Publications, 1982; 390-2, 420-5
  13. Wilhelm DL. Inflammation and Healing. In: Pathology. Anderson WAD, Kissane JM (Eds.). 7th Ed. St. Louis, C.V. Mosby Co., 1977; 22
  14. Hoffmann DF, Cook TA, Quatcla VC, Wang TD, Brownrigg PJ, Brummett RE. Steroids and rhinoplasty: A double-blind study. Arch Otolaryngol Head Neck Surg 1991; 117: 990-3
  15. Cawson RA, James J. Adrenal crisis in dental patient having sys- temic corticosteroids. Br J Oral Surg 1973; 10(3): 305-9.