Journals / Türk Otolarengoloji Arşivi / 2006 / Cilt: 44 - Sayı: 1

Thyroidectomy associated with laryngectomy in laryngeal cancer treatment

Larengeal kanser tedavisinde total larenjektomi beraberinde tiroidektomi

Pages
25–28
Publication Date
2022-11-05
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In some publications, synchronous ipsilateral thyroidectomy is recommended if extralaryngeal or subglottic invasion is identified.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: Surgery is still the first line therapy in advanced laryngeal cancer.
📊
Key Findings & Data:Especially in T3 and T4 laryngeal cancer total laryngectomy is performed frequently.
💡
Conclusion & Impact:In some publications, synchronous ipsilateral thyroidectomy is recommended if extralaryngeal or subglottic invasion is identified.
🔬Design:Research Article
📍Scope:2004 Verileri
⚙️Variables:Domain Parameters

Abstract

Objectives: Surgery is still the first line therapy in advanced laryngeal cancer. Especially in T3 and T4 laryngeal cancer total laryngectomy is performed frequently. In some publications, synchronous ipsilateral thyroidectomy is recommended if extralaryngeal or subglottic invasion is identified. However, hypothyroidism and hypocalcemia were determined in patients after thyroidectomy. In this study we aimed to determine whether thyroidectomy is necessary in the management of advanced laryngeal cancer or not.Methods: We investigated 41 laryngeal cancer patients that had underwent total laryngectomy and ipsilateral thyroidectomy synchronously between 1993 and 2004. The percentage of thyroid invasion of primary tumor was evaluated.Results: We identified only one thyroid metastasis in 41 patients. In 40 patients no thyroid invasion was found.Conclusion: These results were consistent with the literature in which synchronous thyroidectomy was recommended only in selected cases.

Özet

Amaç: İleri evre larenks kanserinin tedavisinde cerrahi tedavi halen ilk sırada yer almaktadır. Total larenjektomi özellikle T3 ve T4 hastalarda sıklıkla uygulanmaktadır. Bazı yayınlarda ekstralarengeal veya subglottik bölgeye tümör yayılımı mevcutsa larenjektomiye ek olarak tiroidektominin de yapılmasını önermektedir. Bununla birlikte hipotiroidi ve hipokalsemi gibi beklenmedik komplikasyonlar gelişebilmektedir. Bu çalışmamızda ileri evre larenks kanserinin tedavisinde tiroidektominin gerekli olup olmadığını ortaya koymayı amaçladık.Yöntem: 1993-2004 yılları arasında kliniğimizde malign larenks tümörü nedeniyle total larenjektomi ve beraberinde ipsilateral tiroidektomi uygulanan 41 hasta taranarak, primer tümörün tiroide invazyon oranı araştırıldı.Bulgular: 41 hastanın sadece birinde tiroide metastaz mevcuttu. 40 hastada tiroid invazyonuna rastlanmadı.Sonuç: Bu sonucun total larenjektomi sırasında eş zamanlı olarak tiroidektominin ancak seçilmiş olgularda yapılması gerektiğini savunan literatürle uyumlu olduğu görüldü.

🔖

Cite This Article

TİTİZ, A., ÜNAL, A., TUNCEL, Ü., ÖZLÜGEDİK, S., SARI, K., TEZER, M. S. (2022). Thyroidectomy associated with laryngectomy in laryngeal cancer treatment. Türk Otolarengoloji Arşivi, Cilt: 44 - Sayı: 1, 25–28. https://ajindex.com/articles/640027

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (20)

  1. Brennan JA, Meyers AD, Jafek BW. The intraopertive management of the thyroid gland during laryngectomy. Laryngoscope 1991; 101: 929-34
  2. Lore JM. Radical surgery of the larynx and laryngopharynx. In: English GM, editor. Otolaryngology. New York: Harper & Row; 1984. p 41
  3. Silver CE. Surgery for cancer of the larynx. New York: Churchill Livingstone; 1981
  4. Sternberg CM, Baily BJ. Transglottic carcinoma and total laryngectomy. In: Bailey BJ, Biller HF, editors. Surgery of the larynx. Philadelphia: WB Saunders; 1985. p. 17-32
  5. Biel MA, Maisel RH. Indications for performing hemithyroidectomy for tumors requiring total laryngectomy. Am J Surg 1985; 150: 435-9
  6. Schaefer RB, Nuttall FQ, Pollak K, et al. Thyroid Function after Radiation nad Surgery for Head and Cancer. Arch Intern Med 1975; 135: 8436
  7. De Jong JM, VonDoal WA, Elte JW, et al. Primary Hypothyroidsm as a Complication After Treatment of Tumors of the Head and Neck. Acta Radiol (Oncol) 1982; 21: 299-303
  8. Murken RE, Duvall AJ. Hypothyroidizm following combined therapy in carcinoma of the laryngopharynx. Laryngoscope 1972; 82: 1306-14
  9. Fagan JJ, Kaye PV. Management of the thyroid gland with laryngectomy for cT3 glottic carcinomas. Clin Otolaryngol Allied Sci 1997; 22: 712
  10. Harrison DF. Thyroid gland in the management of laryngopharyngeal cancer. Arc Otolaryngol 1973; 97: 301-2
  11. Tucker HM. The larynx. New York: Thieme; 1988
  12. Silver CE. Surgery for cancer of the larynx. New York: Churchill Livingstone; 1981
  13. Ogura JH. Surgical pathology of cancer of the larynx. Laryngoscope 1955; 65: 867-926
  14. Reed GF, Mueller W, Snow JB. Radical neck dissection. Laryngoscope 1959; 69: 702-43
  15. Sessions DG. Surgical pathology of cancer of the larynx and hypop-harynx. Laryngoscope 1976; 86: 814-39
  16. Gilbert RW, Cullen RJ, van Nostrand AW, Bryce DP, Harwood AR. Prognostic significance of thyroid galnd involvement in laryngeal carcinoma. Arch Otolaryngol 1986; 112: 856-9
  17. Lam KH. Extralaryngeal spread of cancer of the larynx: a study with whole-organ sections. Head Neck Surg 1983; 5: 410-24
  18. Fagan JJ, D'Amico F, Wagner RL, Johnson JT. Implications of cartilage invasion in surgically treated laryngeal carcinoma. Head Neck 1998; 20: 189-92
  19. Yuen AP, Wei WL, Lam KH, Ho CM. Thyroidectomy during laryngec-tomy for advanced laryngeal carcinoma- whole organ section study with long-term functional evaluation. Clin Otolaryngol Allied Sci 1995; 20: 145-9
  20. Dadaş B, Uslu B,