Journals / Türk Osteoporoz Dergisi / 2011 / Cilt: 17 - Sayı: 3

Vitamin D levels in patients with osteoporosis

Osteoporozlu hastalarda D vitamini düzeyleri

Pages
68–70
Publication Date
2022-11-05
DOI
—
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There is advanced need for studies focusing on risk factors. (Turkish Journal of Osteoporosis 2011;17:68-70)

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: In this study, we aimed to determine vitamin D levels and related parameters of patients referring to our osteoporosis follow-up clinic.
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Key Findings & Data:Material and Methods: Age, gender, occupation, education level, menopausal state, menopause age and vitamin D levels on admission were recorded retrospectively from files of 940 patients, who had been followed between years 2003-2011 at İbn-i Sina osteoporosis follow-up clinic.
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Conclusion & Impact:There is advanced need for studies focusing on risk factors. (Turkish Journal of Osteoporosis 2011;17:68-70)
🔬Design:Research Article
📍Scope:2003-2011 Verileri
⚙️Variables:Domain Parameters

Abstract

Aim: In this study, we aimed to determine vitamin D levels and related parameters of patients referring to our osteoporosis follow-up clinic. Material and Methods: Age, gender, occupation, education level, menopausal state, menopause age and vitamin D levels on admission were recorded retrospectively from files of 940 patients, who had been followed between years 2003-2011 at İbn-i Sina osteoporosis follow-up clinic. Vitamin D levels divided into four groups and accepted as 30-80 mcg/L sufficient, 21-30 mcg/L insufficient, 11-20 mcg/L deficient and 0-10 mcg/L osteomalasic. Results: Mean age of the 940 patients was 61.0±10.8 (23-89) years. 867 (92.2%) were female and 73 (7.8%) were male patients. Most of the patients were housewomen (72.6%). Educational level of the patients was usually primary school (45.6%). The number of menopausal patients was 777 (82.7%) and mean menopause age was 45.69±6.16. The mean vitamin D level of the patients was 26.13±18.62 mcg/L. When we grouped patients according to vitamin D levels, approximately 70% were below normal. Patients who had osteomalasic levels were 16.3%. Patients with sufficient vitamin D levels were 31.5%. There was significant difference between sex and vitamin D levels and it was lower in women (χ2=9.63, p=0.022). No relation was found between occupation, educational level, age, menopause time and vitamin D levels. Conclusion: Approximately 70% of the patients admitted to our osteoporosis follow-up clinic had vitamin D levels lower than normal. In addition, it has been found that vitamin D levels were significantly lower in women. There is advanced need for studies focusing on risk factors. (Turkish Journal of Osteoporosis 2011;17:68-70)

Özet

Amaç: Bu çalışma ile hastanemiz osteoporoz izlem polikliniğine başvuran hastaların D vitamini düzeylerini saptamayı ve ilişkili parametreleri belirlemeyi amaçladık. Gereç ve Yöntem: İbn-i Sina Hastanesi osteoporoz izlem polikliniğinde 2003-2011 yılları arasında takipli 940 hastanın dosyaları üzerinden retrospektif olarak yaş, cinsiyet, meslek, eğitim düzeyi, menapoz durumu ve yaşı ile başvuru anındaki D vitamini düzeyleri kaydedildi. D vitamini düzeyleri 4 gruba ayrıldı: 30-80 mcg/L, yeterli (sufficient); 21-30 mcg/L, yetersiz (insufficient); 11-20 mcg/L, eksik (deficient); 0-10 mcg/L, osteomalazik (osteomalasic) kabul edildi. D vitamini düzeyi, her bir parametreyle istatistiksel olarak karşılaştırıldı. Bulgular: Hastaların yaş ortalaması 61,0±10,8 (23-89) yıl idi. Bu hastalardan 867’si (%92,2) kadın, 73’ü (%7,8) erkekti. Hastaların büyük çoğunluğu ev hanımıydı (%72,6). Hastaların eğitim düzeyi genelde ilkokuldu (%45,6). Hastalardan menopoza girenlerin sayısı 777 (%82,7) ve ortalama menapoz yaşı 45,69±6,16’ydı. Hastaların D vitamini düzeyleri ortalaması 26,13±18,62 mcg/L idi. D vitamini düzeyine göre grupladığımızda yaklaşık %70’inin normalin altında kaldığı görüldü. Osteomalazik düzeyde değerleri olan hasta %16,3’tü. D vitamini düzeyi yeterli olan hasta %31,5’ti. D vitamini düzeyiyle cinsiyet arasında anlamlı fark bulundu ve kadınlarda D vitamini daha düşük saptandı (χ2 =9,63, p=0,022). D vitamini düzeyinin meslek, eğitim düzeyi, yaş ve menopoz süresi ile bir ilişkisi bulunamadı. Sonuç: Osteoporoz izlem polikliniğimize başvuran hastalarda D vitamini düzeyleri %70’e yakın oranda normalin altında bulundu. Ayrıca kadınlarda D vitamini düzeyi anlamlı biçimde daha düşük saptandı. Bu konuda risk faktörlerine odaklı ileri çalışmalara ihtiyaç vardır. (Türk Os te opo roz Dergisi 2011;17:68-70)

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Cite This Article

DİNÇER, G., YALÇIN, P., KURT, M., CÖMERTOĞLU, İ., SARP, Ü. (2022). Vitamin D levels in patients with osteoporosis. Türk Osteoporoz Dergisi, Cilt: 17 - Sayı: 3, 68–70. https://ajindex.com/articles/639903

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References (13)

  1. Gallagher JC, Sai AJ. Vitamin D insufficiency, deficiency, and bone health. J Clin Endocrinol Metab 2010;95:2630-3
  2. Pérez-López FR, Brincat M, Erel CT, Tremollieres F, Gambacciani M, Lambrinoudaki I, et al. EMAS position statement: Vitamin D and postmenopausal health. Maturitas. 2011 Nov 17. [Epub ahead of print] 3. Zhang R, Naughton DP. Vitamin D in health and disease: current perspectives. Nutr J 2010;9:65
  3. Cannell JJ, Hollis BW, Zasloff M, Heaney RP. Diagnosis and treatment of vitamin D deficiency. Expert Opin. Pharmacother 2008;9:107-18. 5. de Paula FJ, Rosen CJ. Vitamin D safety and requirements. Arch Biochem Biophys 2011 (In Press)
  4. Gómez Alonso C, Naves Díaz M, Rodríguez García M, Fernández Martín JL, Cannata Andía JB. [Review of the concept of vitamin D "sufficiency and insufficiency"]. Nefrologia 2003;23:73-7
  5. Holick MF. Vitamin D deficiency. N Engl J Med 2007;357:266-81
  6. Iqbal R, Khan AH. Possible causes of vitamin D deficiency (VDD) in Pakistani population residing in Pakistan. J Pak Med Assoc 2010;60:1-2
  7. Miljkovic I, Bodnar LM, Cauley JA, Bunker CH, Patrick AL, Wheeler VW, et al. Low prevalence of vitamin D deficiency in elderly Afro- Caribbean men. Ethn Dis 2011;21:79-84
  8. Mithal A, Wahl DA, Bonjour JP, Burckhardt P, Dawson-Hughes B, Eisman JA, et al. IOF Committee of Scientific Advisors (CSA) Nutrition Working Group. Global vitamin D status and determinants of hypovitaminosis D. Osteoporos Int 2009;20:1807-20
  9. Dixon T, Mitchell P, Beringer T, Gallacher S, Moniz C, Patel S, et al. An overview of the prevalence of 25-hydroxy-vitamin D inadequacy amongst elderly patients with or without fragility fracture in the United Kingdom. Curr Med Res Opin 2006;22:405-15
  10. Kuroda T, Shiraki M, Tanaka S, Ohta H. Contributions of 25- hydroxyvitamin D, co-morbidities and bone mass to mortality in Japanese postmenopausal women. Bone 2009;44:168-72
  11. Gaugris S, Heaney RP, Boonen S, Kurth H, Bentkover JD, Sen SS. Vitamin D inadequacy among post-menopausal women: a systematic review. QJM 2005;98:667-76
  12. Erkal MZ, Wilde J, Bilgin Y, Akinci A, Demir E, Bödeker RH, et al. High prevalence of vitamin D deficiency, secondary hyperparathyroidism and generalized bone pain in Turkish immigrants in Germany: identification of risk factors. Osteoporos Int 2006;17:1133-40
  13. Guzel R, Kozanoglu E, Guler-Uysal F, Soyupak S, Sarpel T. Vitamin D Status and Bone Mineral Density of Veiled and Unveiled Turkish Women. J Womens Health Gend Base