AI Summary & Key Takeaways
AI InsightIn this study, we investigated this mechanism by measuring serum endocan levels and CIMT in patientswith FMS and evaluated whether there is a correlation between them.Materials and Methods: Serum samples collected from 40 female patients diagnosed with FMS (the patient group) for the first time and40 healthy female participants’ (the control group) endocan levels and CIMT ultrasonography were investigated, and the values of the twogroups were compared.Results: Serum endocan levels and CIMT results were significantly higher in the patient group than in the control group (p
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Abstract
Objective: Although the pathophysiology of Fibromyalgia syndrome (FMS) has not yet been completely elucidated, it has been suggestedthat inflammation and endothelial dysfunction occur in patients with FMS. In recent years, endocan has been reported as an importantbiomarker for inflammation and endothelial dysfunction. It is important to assess carotid intima-media thickness (CIMT) in the evaluation ofearly atherosclerotic vascular diseases. In this study, we investigated this mechanism by measuring serum endocan levels and CIMT in patientswith FMS and evaluated whether there is a correlation between them.Materials and Methods: Serum samples collected from 40 female patients diagnosed with FMS (the patient group) for the first time and40 healthy female participants’ (the control group) endocan levels and CIMT ultrasonography were investigated, and the values of the twogroups were compared.Results: Serum endocan levels and CIMT results were significantly higher in the patient group than in the control group (p
Özet
Amaç: Fibromiyaljinin patofizyolojisi henüz tam olarak aydınlatılmamış olmakla birlikte, fibromiyaljili hastalarda enflamasyon ve endotel disfonksiyonunun ortaya çıktığı ileri sürülmüştür. Son yıllarda, endokan enflamasyon ve endotel disfonksiyonu için önemli bir biyobelirteç olarak bildirilmiştir. Erken aterosklerotik vasküler hastalıkları değerlendirmede karotis intima media-kalınlığının (KİMK) değerlendirilmesi önemlidir. Bu çalışmada, fibromiyalji hastalarında serum endokan düzeylerini ve KİMK’yi ölçerek bu mekanizmayı araştırdık, aralarında bir korelasyon olup olmadığını değerlendirdik. Gereç ve Yöntem: İlk kez fibromiyalji tanısı alan 40 kadın hastadan toplanan serum örnekleri ve 40 sağlıklı kadın endokan düzeyleri ve KİMK ultrasonografi ile incelendi ve iki grubun değerleri karşılaştırıldı. Bulgular: Hasta grubunda serum endokan seviyeleri ve KİMK sonuçları kontrol grubuna göre anlamlı olarak yüksek olarak bulunmuştur (p