Journals / Türk Osteoporoz Dergisi / 2019 / Cilt: 25 - Sayı: 2

Investigation of Short-wave Diathermy Genotoxic Effect in Patients with Knee Osteoarthritis

Diz Osteoartriti Olan Hastalarda Kısa Dalga Diaterminin Genotoksik Etkisinin Araştırılması

Pages
53–57
Publication Date
2022-11-04
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was also not a significant difference in the MN scores of the groups between pre-treatment and after 10th sessionof SWD therapy (p>0.05).Conclusion: In this study, we observed that the therapeutic SWD did not induce an increase in MN score, which is a sign of cytogeneticdamage.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Short-wave diathermy (SWD) is a physical therapy agent that is commonly used as a deep heater in physical medicine practices.The aim of this study was to investigate whether there is a chromosomal damage arising from therapeutic SWD by using micronucleus (MN)method.Materials and Methods: Thirty patients who suffered from knee pain, and diagnosed as gonarthrosis according to American College ofRheumatology criteria were admitted in the present study.
📊
Key Findings & Data:Twenty patients were assigned as the treatment group (group 1) and 10 patientswere assigned as the control group (group 2).
💡
Conclusion & Impact:There was also not a significant difference in the MN scores of the groups between pre-treatment and after 10th sessionof SWD therapy (p>0.05).Conclusion: In this study, we observed that the therapeutic SWD did not induce an increase in MN score, which is a sign of cytogeneticdamage.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Short-wave diathermy (SWD) is a physical therapy agent that is commonly used as a deep heater in physical medicine practices.The aim of this study was to investigate whether there is a chromosomal damage arising from therapeutic SWD by using micronucleus (MN)method.Materials and Methods: Thirty patients who suffered from knee pain, and diagnosed as gonarthrosis according to American College ofRheumatology criteria were admitted in the present study. Twenty patients were assigned as the treatment group (group 1) and 10 patientswere assigned as the control group (group 2). The patients in the treatment group received 10 sessions of SWD therapy, whereas the patientsin the control group received 10 sessions of sham SWD therapy. Peripheral venous blood was obtained from both the treatment and thecontrol groups before and after 10 sessions of SWD therapy to evaluate MN scores. The scores of MN assessed before the therapy werecompared with the MN scores at the end of 10 sessions of SWD therapy in the treatment and the control groups. Pre-treatment and end ofthe 10th session MN scores were compared between the treatment and the control groups.Results: There was not a statistically significant difference in MN scores between pre-treatment and after 10th session SWD therapy in bothgroups (p>0.05). There was also not a significant difference in the MN scores of the groups between pre-treatment and after 10th sessionof SWD therapy (p>0.05).Conclusion: In this study, we observed that the therapeutic SWD did not induce an increase in MN score, which is a sign of cytogeneticdamage.

Özet

Amaç: Kısa dalga diatermi (KDD), fiziksel tıp uygulamalarında genellikle derin ısıtıcı olarak kullanılan bir fizik tedavi ajanıdır. Bu çalışmanın amacı, terapötik KDD’den kaynaklanan bir kromozomal hasar olup olmadığını mikronükleus (MN) yöntemiyle araştırmaktır. Gereç ve Yöntem: Çalışmaya diz ağrısı olan ve Amerikan Romatoloji Koleji kriterleri ile gonartroz tanısı alan 30 hasta dahil edildi. Yirmi hasta tedavi grubu (grup 1), 10 hasta kontrol grubu (grup 2) olarak tayin edildi. Tedavi grubundaki hastalara 10 seans KDD tedavisi uygulandı, kontrol grubundaki hastalara ise 10 seans sahte KDD tedavisi uygulandı. MN skorlarını değerlendirmek için periferik venöz kan, hem tedavi hem de kontrol grubundan 10 seans KDD tedavisi uygulaması öncesi ve sonrasında alındı. Tedavi öncesi değerlendirilen MN skorları, tedavi grubunda ve kontrol gruplarında 10 seans KDD tedavisi sonu MN skorları ile karşılaştırıldı. Tedavi öncesi ve 10 seans KDD tedavi sonrası MN skorları tedavi ve kontrol grubu arasında karşılaştırıldı. Bulgular: Her iki grubun KDD tedavisi öncesi ile 10 seans KDD tedavisi sonrasında MN skorları arasında istatistiksel olarak anlamlı bir fark yoktu (p>0,05). Grupların MN skorları karşılaştırıldığında KDD tedavisi öncesi ve 10 seans KDD tedavisi sonrasında MN skorları açısından gruplar arasında anlamlı bir fark yoktu (p>0,05). Sonuç: Bu çalışmada, terapötik KDD’nin, sitogenetik hasarın bir işareti olan MN skorunda artışa neden olmadığını gözlemledik.

🔖

Cite This Article

KARADAĞ, A., ŞENER, Ö., HAYTA, E., HİZMETLİ, S. (2022). Investigation of Short-wave Diathermy Genotoxic Effect in Patients with Knee Osteoarthritis. Türk Osteoporoz Dergisi, Cilt: 25 - Sayı: 2, 53–57. https://ajindex.com/articles/639674

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Wang H, Zhang C, Gao C, Zhu S, Yang L, Wei Q, et al. Effects of short-wave therapy in patients with knee osteoarthritis: a systematic review and meta-analysis. Clin Rehabil 2017;31:660- 71
  2. Zeng C, Gao SG, Lei GH. Comment on Laufer et al. entitled “Effectiveness of thermal and athermal short-wave diathermy for the management of knee osteoarthritis: a systematic review and meta-analysis”. Osteoarthritis Cartilage 2014;22:605-6
  3. Incebiyik S, Boyaci A, Tutoglu A. Short-term effectiveness of short-wave diathermy treatment on pain, clinical symptoms, and hand function in patients with mild or moderate idiopathic carpal tunnel syndrome. J Back Musculoskelet Rehabil 2015;28:221-8
  4. Al-Mandeel MM, Watson T. The thermal and nonthermal effects of high and low doses of pulsed short wave therapy (PSWT). Physiother Res Int 2010;15:199-211
  5. Israel M, Zaryabova V, Ivanova M. Electromagnetic field occupational exposure: non-thermal vs. thermal effects. Electromagn Biol Med 2013;32:145-54
  6. Lehman JF, De Lateur BJ. Diathermy and superficial heat, laser and cold therapy. In: Kottle, Lehmann editors. Krusen’s Handbook of Physical Medicine and Rehabilitation. Philadelphia: W.B. Saunders 1990;283-6
  7. Kesari KK, Siddiqui MH, Meena R, Verma HN, Kumar S. Cell phone radiation exposure on brain and associated biological systems. Indian J Exp Biol 2013;51:187-200
  8. Meltz ML. Radiofrequency exposure and mammalian cell toxicity, genotoxicity, and transformation. Bioelectromagnetics 2003;6:196-213
  9. Cardinale F, Bruzzi P, Bolognesi C. Role of micronucleus test in predicting breast cancer susceptibility: a systematic review and meta-analysis. Br J Cancer 2012;106:780-90
  10. Fenech M, Denham J, Francis W, Morley A. Micronuclei in cytokinesis-blocked lymphocytes of cancer patients following fractionated partial-body radiotherapy. Int J Radiat Biol 1990;57:373-83
  11. Zacher J, Carl HD, Swoboda B, Backhaus M. Imaging of osteoarthritis of the peripheral joints. Z Rheumatol 2007;66:257- 8
  12. Fenech M, Holland N, Chang WP, Zeiger E, Bonassi S. The HUman MicroNucleus Project--An international collaborative study on the use of the micronucleus technique for measuring DNA damage in humans. Mutat Res 1999;428:271-83
  13. Balasem AN, Ali AS. Establishment of dose-response relationships between doses of Cs-137 gamma-rays and frequencies of micronuclei in human peripheral blood lymphocytes. Mutat Res 1991;259:133-8
  14. Fenech M. The cytokinesis-block micronucleus technique: