Journals / Türk Osteoporoz Dergisi / 2019 / Cilt: 25 - Sayı: 3

Examination of the Etiologic Causes in Patients Presenting with Elevated Parathormone

Parathormon Yüksekliği ile Başvuran Hastalarda Etiyolojik Nedenlerin İncelenmesi

Pages
111–114
Publication Date
2022-11-03
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The other reason such as PHPT, FHHand CRF must be also investigated.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Parathyroid hormone (PTH) levels are elevated in the blood due to various reasons and named as primary or secondaryhyperparathyroidism.
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Key Findings & Data:There is no any study that investigated the etiology of elevated PTH.Materials and Methods: The study included 137 patients who had elevated PTH, which was detected in blood tests that were performeddue to any reason, during 1-year period.Results: Of all patients 118 (86.1%) were female and 19 (13.9%) were male.
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Conclusion & Impact:The other reason such as PHPT, FHHand CRF must be also investigated.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Parathyroid hormone (PTH) levels are elevated in the blood due to various reasons and named as primary or secondaryhyperparathyroidism. There is no any study that investigated the etiology of elevated PTH.Materials and Methods: The study included 137 patients who had elevated PTH, which was detected in blood tests that were performeddue to any reason, during 1-year period.Results: Of all patients 118 (86.1%) were female and 19 (13.9%) were male. Vitamin D deficiency was found in 88 (64.2%), primaryhyperparathyroidism (PHPT) in 38 (27.7%), familial hypocalciuric hypercalcemia (FHH) in 8 (5.8%), and chronic renal failure (CRF) in 3 (2.2%)patients.Conclusion: Vitamin D deficiency is a common disorder in general population, and occasionally coexisted with increased PTH level. Therefore,vitamin D deficiency should be kept in mind when PTH studied as a first test and is found to be high. The other reason such as PHPT, FHHand CRF must be also investigated.

Özet

Amaç: Parathormon (PTH) düzeyi kanda çeşitli nedenlerle yükselir ve primer veya sekonder hiperparatiroidizm olarak adlandırılır. PTH yüksekliğinin etiyolojisini araştıran herhangi bir çalışma yoktur. Gereç ve Yöntem: Çalışmaya 1 yıllık süre içerisinde herhangi bir sebeple yapılan kan testlerinde saptanan PTH yüksek bulunmuş 137 hasta dahil edildi. Bulgular: Tüm hastaların 118’i (%86,1) kadın, 19’u (%13,9) erkekti. D vitamini eksikliği 88’inde (%64,2), primer hiperparatiroidizm (PHPT) 38’inde %27,7’sinde ailesel hipokalsiürik hiperkalsemi (AHH), 8’inde (%5,8) ve 3’ünde (%2,2) kronik böbrek yetmezliği (KBY) tespit edildi. Sonuç: D vitamini eksikliği, genel popülasyonda sık görülen bir hastalıktır ve bazen artan PTH düzeyi ile birlikte bulunur. Bu nedenle, PTH ilk test olarak okunduğu ve yüksek olduğu tespit edildiğinde D vitamini eksikliği akılda tutulmalıdır. PHPT, AHH ve KBY gibi diğer sebepler de araştırılmalıdır.

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Cite This Article

KIRHAN, İ., EREN, M. A. (2022). Examination of the Etiologic Causes in Patients Presenting with Elevated Parathormone. Türk Osteoporoz Dergisi, Cilt: 25 - Sayı: 3, 111–114. https://ajindex.com/articles/639673

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