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Journals / Türk Osteoporoz Dergisi / 2020 / Cilt: 26 - Sayı: 2

Serum Melatonin Levels in Patients with Behçet’s Disease

Behçet Hastalığı Olan Hastalarda Serum Melatonin Düzeyleri

Nurinnisa ÖZTÜRK
Ayhan KUL
Fatih BAYGUTALP
Yaşar ARSLAN
Pages
104–109
Publication Date
2022-11-06
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The relationship between disease activity and serum MLT level was examined.Results: There were no significant differences in the demographic characteristics and other laboratory parameters between the groups, except for serum MLT levels and mean platelet volume values (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Melatonin (MLT) hormone has been reported to play a role in the immunopathogenesis and aetiology of many chronic inflammatory diseases.
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Key Findings & Data:We aimed to investigate the role of MLT in Behçet’s disease (BD) by determining the serum MLT levels of patients with BD.Materials and Methods: A total of 40 patients (mean age, 35.3±9.0 years; age range, 19-57 years), including 19 women and 21 men, and 40 healthy individuals, including 20 women and 20 men, matched for age and gender (mean age, 37.7±11.2 years; age range, 19-65 years) were included in this study.
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Conclusion & Impact:The relationship between disease activity and serum MLT level was examined.Results: There were no significant differences in the demographic characteristics and other laboratory parameters between the groups, except for serum MLT levels and mean platelet volume values (p
🔬Design:Research Article
📍Scope:2006 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Melatonin (MLT) hormone has been reported to play a role in the immunopathogenesis and aetiology of many chronic inflammatory diseases. We aimed to investigate the role of MLT in Behçet’s disease (BD) by determining the serum MLT levels of patients with BD.Materials and Methods: A total of 40 patients (mean age, 35.3±9.0 years; age range, 19-57 years), including 19 women and 21 men, and 40 healthy individuals, including 20 women and 20 men, matched for age and gender (mean age, 37.7±11.2 years; age range, 19-65 years) were included in this study. Serum MLT levels of the participants were determined, and their demographic data, laboratory parameters, and clinical features were recorded. Disease activity was evaluated according to the BD current activity form 2006. The relationship between disease activity and serum MLT level was examined.Results: There were no significant differences in the demographic characteristics and other laboratory parameters between the groups, except for serum MLT levels and mean platelet volume values (p

Özet

Amaç: Melatoninleri (MLT) hormonunun birçok kronik enflamatuvar hastalığın immünopatogenezinde ve etiyolojisinde rol oynayabileceği bildirildiğinden dolayı, çalışmamızda Behçet hastalığı (BH) olan hastaların serum MLT seviyelerinin belirlenerek hastalık aktivitesi ile arasında olası bir ilişki olup olmadığını incelemeyi amaçladık. Gereç ve Yöntem: Çalışmada 19 kadın ve 21 erkek olmak üzere toplam 40 hasta (ortalama yaş; 35,3±9,0 yıl; yaş aralığı; 19-57 yıl) ile yaş ve cinsiyetleri benzer olan 20 kadın ve 20 erkek toplam 40 sağlıklı kontrol (ortalama yaş; 37,7±11,2 yıl; yaş aralığı;19-65 yıl) bulunmaktaydı. Katılımcıların demografik verileri, laboratuvar ve klinik özellikleri kaydedilerek serum MLT seviyeleri belirlendi. BH anlık aktivite form-2006’ya göre hastalık aktivitesi değerlendirildi. Hastalık aktivitesi ile serum MLT seviyesi arasındaki ilişki incelendi. Bulgular: Gruplar arasında serum MLT düzeyleri ve ortalama trombosit hacmi değerleri hariç (p

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Cite This Article

ÖZTÜRK, N., KUL, A., BAYGUTALP, F., ARSLAN, Y. (2022). Serum Melatonin Levels in Patients with Behçet’s Disease. Türk Osteoporoz Dergisi, Cilt: 26 - Sayı: 2, 104–109. https://ajindex.com/articles/639634

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