Journals / Türk Osteoporoz Dergisi / 2021 / Cilt: 27 - Sayı: 2

Vertebral Sarcoidosis: A Rare Case Report

Vertebral Sarkoidoz: Nadir Bir Olgu Sunumu

Pages
114–116
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It should be differentially diagnosed from metastatic lesions

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Sarcoidosis is a disease characterized by noncaseating granulomas that can affect many tissues and organs, especially the lungs.
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Key Findings & Data:In sarcoidosis, osteopenia, osteoporosis and pathological bone fractures can be seen with the direct effect of granulomas, osteoclast activating factors such as 1.25-dihydroxyvitamin D released from macrophages, and the use of glucocorticoids.
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Conclusion & Impact:It should be differentially diagnosed from metastatic lesions
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Sarcoidosis is a disease characterized by noncaseating granulomas that can affect many tissues and organs, especially the lungs. In sarcoidosis, osteopenia, osteoporosis and pathological bone fractures can be seen with the direct effect of granulomas, osteoclast activating factors such as 1.25-dihydroxyvitamin D released from macrophages, and the use of glucocorticoids. Bone involvement of sarcoidosis produces typical cystic structures in the hands and feet. Vertebral involvement is rare and may cause lytic, sclerotic or mixed lesions. It should be differentially diagnosed from metastatic lesions

Özet

Sarkoidoz, non-kazeifiye granülomlarla karakterize, başta akciğerler olmak üzere, pek çok doku ve organı etkileyebilen bir hastalıktır. Sarkoidozda,granülomların direkt etkisi, makrofajlardan salınan 1,25-dihidroksivitamin D gibi osteoklast aktive edici faktörler ve glukokortikoidlerin kullanımıile osteopeni, osteoporoz ve patolojik kemik kırıkları görülebilir. Sarkoidozun kemik tutulumu, el ve ayakta tipik kistik yapılar meydana getirir.Vertebral tutulum ise nadirdir ve litik, sklerotik veya mikst lezyonlara neden olabilir. Metastatik lezyonlar ile ayırıcı tanı yapılmalıdır.

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Cite This Article

KESKİN, A. S. B., REŞORLU, H. (2022). Vertebral Sarcoidosis: A Rare Case Report. Türk Osteoporoz Dergisi, Cilt: 27 - Sayı: 2, 114–116. https://ajindex.com/articles/639590

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