Relationship Between Severity of Obstructive Sleep Apnea and PR Interval

Harun KARAMANLI; Fatih AYGÜN; Recep AKGEDİK

Journals / Koşuyolu Heart Journal / 2016 / Cilt: 19 - Sayı: 1

Relationship Between Severity of Obstructive Sleep Apnea and PR Interval

Obstrüktif Uyku Apnesi Şiddeti ve PR Süresi Arasındaki İlişki

Harun KARAMANLI

Fatih AYGÜN

Recep AKGEDİK

Journal: Koşuyolu Heart Journal
Issue: 2016 · Cilt: 19 - Sayı: 1
Pages: 27–31
Publication Date: 2016-04-04
DOI: —

🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.

DergiPark Record ↗

✨

AI Summary & Key Takeaways

AI Insight

⚡ TL;DR(Too Long; Didn't Read)

We believe that apnea-hypopnea index, oxygen desaturation index, and arousal values, which are indications of OSA severity and parameters of hypoxia-reoxygenation, contribute to PR prolongation.

📌 3 Key Takeaways

🎯

Objective & Hypothesis: Introduction: Relationship between obstructive sleep apnea (OSA) and electrocardiogram and OSA severity index relationship that may affect the PR interval were studied.

📊

Key Findings & Data:Patients and Methods: This study included 85 people who had OSA diagnosed at our clinic between January 2013 and August 2013.

💡

Conclusion & Impact:We believe that apnea-hypopnea index, oxygen desaturation index, and arousal values, which are indications of OSA severity and parameters of hypoxia-reoxygenation, contribute to PR prolongation.

🔬Design:Research Article

📍Scope:2013 Verileri

⚙️Variables:PR aralığı süresi · obstrüktif uyku apnesi · PR interval time

Abstract

Introduction: Relationship between obstructive sleep apnea (OSA) and electrocardiogram and OSA severity index relationship that may affect the PR interval were studied. Patients and Methods: This study included 85 people who had OSA diagnosed at our clinic between January 2013 and August 2013. Their polysomnography (PSG) reports were evaluated by physicians who are expert in their fields. Individuals with severe OSA diseases were categorized as group 1, and individuals with mild to moderate OSA were categorized as group 2. Results: Age distribution of individuals who participated to the study ranged from 20 years to 85 years (mean ± standard deviation, 45.5 ± 13.2 years). Fifty-one (60%) of those individuals were men, and 34 (40%) of them were women. The PR interval for the group who had severe OSA on PSG (group 1) was 163.1 ± 35.2 ms, and it was 147.8 ± 29.3 in group 2. Conclusion: It was observed that individuals having severe OSA had higher PR intervals than individuals who had mild to moderate OSA. It was determined that results were statistically significant (p< 0.05, p= 0.032). We believe that apnea-hypopnea index, oxygen desaturation index, and arousal values, which are indications of OSA severity and parameters of hypoxia-reoxygenation, contribute to PR prolongation.

Özet

Giriş: Obstriktif uyku apnesi (OSA) şiddeti ile elektrokardiyogramdaki PR süresinin genişlemesi arasındaki ilişki ve PR süresini etkileyebilecek OSA şiddet indeksleri ile ilişkisi araştırılmıştır. Hastalar ve Yöntem: Bu çalışma; kliniğimizde Ocak 2013 ve Ağustos 2014 tarihleri arasında, OSA tanısı almış 85 kişiyi içermektedir. Polisomnografi (PSG) raporları alanında uzman hekim tarafından değerlendirildi. Şiddetli uyku apne hastalığı olan bireyler grup 1 olarak adlandırılırken, orta, hafif uyku apne hastalığı olan bireyler grup 2 olarak belirlendi. Bulgular: Çalışmaya katılan tüm bireylerin yaş dağılımı; minimum 20 yıl, maksimum 85 yıldır (ortalama ± standart sapma 45.5 ± 13.2 y). Bu kişilerin 51’i (%60) erkek, 34’ü (%40) kadındır. Polisomnografi şiddetli OSA tanısı alan bireyleri içeren grup 1’de PR süresi 163.1 ± 35.2 milisaniye (ms) iken grup 2’de 147.8 ± 29.3 milisaniye olduğu görüldü. Sonuç: Şiddetli OSA tanısı alan bireylerin, hafif ve orta şiddette OSA tanısı alan bireylere göre PR sürelerinin yüksek olduğu görüldü. Sonucun istatiksel olarak anlamlı olduğu tespit edildi (p< 0.05, p= 0). OSA şiddeti göstergesi ve hipoksi-reoksijenizasyon parametreleri olan AHI (apne-hipopne indeksi), ODI (oksijen desaturasyon indeksi); arousal değerleri PR uzamasında katkı sağladığına inanmaktayız.

Keywords

PR aralığı süresi obstrüktif uyku apnesi PR interval time sleep apnea obstructive

🔖

Cite This Article

KARAMANLI, H., AYGÜN, F., AKGEDİK, R. (2016). Relationship Between Severity of Obstructive Sleep Apnea and PR Interval. Koşuyolu Heart Journal, Cilt: 19 - Sayı: 1, 27–31. https://ajindex.com/articles/63951

📄 Full Text PDF Viewer

Open in New Tab ↗

↗New Tab

📄

PDF görüntüleyici hazırlanıyor...

References (13)

Bonsignore MR, Marrone O, Insalaco G, Bonsignore G. The cardiovascular effects of obstructive sleep apnoeas: analysis of pathogenic mechanisms. Eur Respir J 1994;7:786-805
Fletcher EC, DeBehnke RD, Lovoi MS, Gorin AB. Undiagnosed sleep apnea in patients with essential hypertension. Ann Intern Med 1985;103:190-5
Peker Y, Hedner J, Norum J, Kraiczi H, Carlson J. Increased incidence of cardiovascular disease in middle-aged men with obstructive sleep apnea: a 7-year follow-up. Am J Respir Crit Care Med 2002;166:159-65
Gami AS, Howard DE, Olson EJ, Somers VK. Day-night pattern of sudden death in obstructive sleep apnea. N Engl J Med 2005;352:1206-14
Huikuri HV, Castellanos A, Myerburg RJ, Sudden death due to cardiac arrhythmias. N Engl J Med 2001;345:1473-82
O’Driscoll DM, Meadows GE, Corfield DR, Simonds AK, Morrell MJ. Cardiovascular response to arousal from sleep under controlled conditions of central and peripheral chemoreceptor stimulation in humans. J Appl Physiol (1985) 2004;96:865-70
Otto ME, Belohlavek M, Romero-Corral A, Gami AS, Gilman G, Svatikova A, et al. Comparison of cardiac structural and functional changes in obese otherwise healthy adults with versus without obstructive sleep apnea. Am J Cardiol 2007;99:1298-302
Chung M-H, Kuo TBJ, Hsu N, Chu H, Chou K-R, Yang CCH. Sleep and autonomic nervous system changes - enhanced cardiac sympathetic modulations during sleep in permanent night shift nurses. Scand J Work Environ Health 2009;35:180-7
Bitter T, Horstkotte D, Oldenburg O. [Sleep disordered breathing and cardiac arrhythmias: mechanisms, interactions, and clinical relevance]. Dtsch Med Wochenschr 2011;136:431-5
Maeno K, Kasagi S, Ueda A, Kawana F, Ishiwata S, Ohno M, et al. Effects of obstructive sleep apnea and its treatment on signal-averaged P-wave duration in men. Circ Arrhythm Electrophysiol 2013;6:287-93
Somers VK, Dyken ME, Mark AL, Abboud FM. Parasympathetic hyperresponsiveness and bradyarrhythmias during apnoea in hypertension. Clin Auton Res 1992;2:171-6
Armour JA, Richer LP, Pagé P, Vinet A, Kus T, Vermeulen M, et al. Origin and pharmacological response of atrial tachyarrhythmias induced by activation of mediastinal nerves in canines. Auton Neurosci 2005;118:68-78
Budeus M, Hennersdorf M, Felix O, Reimert K, Perings C, Wieneke H, et al. Prediction of atrial fibrillation in patients with cardiac dysfunctions: P wave signal-averaged ECG and chemoreflexsensitivity in atrial fibrilla