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Journals / Journal of Health Sciences and Medicine / 2022 / Cilt: 5 - Sayı: 2

Association between vitamin D levels and frequency of disease exacerbations and hospitalizations in patients with COPD

Sertan BULUT
Harun KARAMANLI
Mustafa Engin ŞAHİN
Deniz ÇELİK
Çiğdem BİBER
Pages
471–477
Publication Date
2022-03-15
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: 25-hydroxyvitamin D deficiency is a frequent occurrence in COPD and is correlated with the frequency of exacerbation and hospitalization in COPD patients.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: Chronic obstructive pulmonary disease (COPD) is a debilitating disorder that restricts the physical activity of patients who are deprived of sunlight, which is a source of vitamin D.
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Key Findings & Data:Material and Method: In the main analysis, 303 patients with COPD (stage GOLD A to D) were included in a retrospective cohort study in Turkey.
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Conclusion & Impact:Conclusion: 25-hydroxyvitamin D deficiency is a frequent occurrence in COPD and is correlated with the frequency of exacerbation and hospitalization in COPD patients.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Vitamin D · COPD · COPD exacerbation

Abstract

Introduction: Chronic obstructive pulmonary disease (COPD) is a debilitating disorder that restricts the physical activity of patients who are deprived of sunlight, which is a source of vitamin D. The purpose of this study was to assess the relationship between vitamin D and the frequency of exacerbation and hospitalization among patients with COPD. Material and Method: In the main analysis, 303 patients with COPD (stage GOLD A to D) were included in a retrospective cohort study in Turkey. Serum levels of vitamin D (25-hydroxyvitamin D) were measured in 303 patients with COPD and were associated with pulmonary function, AECOPD frequency and hospitalization in the previous year. Results: For COPD patients, the mean reference level of 25 hydroxyvitamin D in serum was 12.5 ng/dL. In comparison to patients with a serious 25-hydroxyvitamin D deficiency ( 30 ng/dL, n=34 [11,2%]), the risk was lower but not significant (incidence ratio, 0.7 [95% CI, 0.2-1.2]. In COPD patients, 25-hydroxyvitamin D rates are low correlated with 1-s forced expiratory volume (FEV1) (r=0.187, p=0.0013). Conclusion: 25-hydroxyvitamin D deficiency is a frequent occurrence in COPD and is correlated with the frequency of exacerbation and hospitalization in COPD patients.

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Cite This Article

BULUT, S., KARAMANLI, H., ŞAHİN, M. E., ÇELİK, D., BİBER, Ç. (2022). Association between vitamin D levels and frequency of disease exacerbations and hospitalizations in patients with COPD. Journal of Health Sciences and Medicine, Cilt: 5 - Sayı: 2, 471–477. https://ajindex.com/articles/776593

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