Journals / Türk Nöroloji Dergisi / 2007 / Cilt: 13 - Sayı: 5

Cerabellar cognitive affective syndrome

Serebellar bilişsel duygulanımsal bozukluk

Pages
333–338
Publication Date
2022-11-05
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

The cognitive deficits resulting from cerebellar pathology may be related to the disruption of cerebello-cortical connections involving a complex network which includes the prefrontal region, suggesting that the cerebellum may process cortical information coming from different brain areas linked with the control of cognition.

📌 3 Key Takeaways

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Objective & Hypothesis:Scientific BACKGROUND: For the last two decades the traditional role of cerebellum that is dedicated exclusively to motor control and coordination has been evolved as recent findings demonstrate its contribution to cognitive processing and emotional regulation.
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Key Findings & Data:CASE: We report a 46 years old patient with an acute onset and permanent frontal-executive disturbance, psychomotor slowing, emotional instability and forgetfulness following a head trauma.
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Conclusion & Impact:The cognitive deficits resulting from cerebellar pathology may be related to the disruption of cerebello-cortical connections involving a complex network which includes the prefrontal region, suggesting that the cerebellum may process cortical information coming from different brain areas linked with the control of cognition.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Scientific BACKGROUND: For the last two decades the traditional role of cerebellum that is dedicated exclusively to motor control and coordination has been evolved as recent findings demonstrate its contribution to cognitive processing and emotional regulation. There is a growing body of evidence of the impact of cerebellar lesions on emotional and cognitive, especially fronto-executive functions. OBJECTIVE: We aimed in this article to mention contribution of the cerebellum to cognitive and behavioral processes. CASE: We report a 46 years old patient with an acute onset and permanent frontal-executive disturbance, psychomotor slowing, emotional instability and forgetfulness following a head trauma. Cranial MRI revealed extensive left cerebellar hemispheric lesions. Deficits of attention, executive function, affect and memory suggest a "cerebellar cognitive affective syndrome" CONCLUSION: Clinical findings of this case are consistent with the role of the cerebellum as a modulator of mental functions. The cognitive deficits resulting from cerebellar pathology may be related to the disruption of cerebello-cortical connections involving a complex network which includes the prefrontal region, suggesting that the cerebellum may process cortical information coming from different brain areas linked with the control of cognition.

Özet

Bilimsel zemin: Serebellumun geleneksel olarak motor kontrol ve koordinasyona indirgenmiş olan rolü, onun duygudurum ve bilişsel işlevler üzerindeki etkisini ortaya koyan yeni veriler ışığında son yirmi yıldır şekil değiştirmeye başlamıştır. Serebellumun bilişsel-yürütücü işlevler ve duygudurum üzerindeki etkilerine ilişkin veriler ve bu konuyla ilgili çalışmalar giderek artmaktadır. AMAÇ: Bu yazının amacı serebellumun bilişsel ve davranışsal işlevler üzerindeki etkisine dikkat çekmektir. OLGU: Kafa travması ardından gelişen, ani başlangıçlı ve kalıcı frontal-yürütücü işlev bozukluğu, psikomotor yavaşlama, duygulanımsal değişkenlik ve unutkanlık yakınmaları olan, 46 yaşında bir erkek olgu bildirilmiştir. Hastanın kranial MRG tetkiki ile sol serebellar hemisferik lezyonu olduğu ortaya konmuştur. Hastada gözlenen dikkat, yürütücü işlevler, duygulanım ve bellekteki bozulmalar nedeniyle olgu serebellar bilişsel duygulanımsal bozukluk olarak değerlendirilmiştir. SONUÇ: Olgumuzda mevcut klinik tablo serebellumun mental fonksiyonlardaki düzenleyici rolü ile örtüşmektedir. Serebellar patolojiye bağlı bilişsel bozukluklar, prefrontal korteks gibi kortikal alanlar ile serebellum arasındaki karmaşık bağlantıların hasarı sonucunda, serebellumun değişik kortikal alanlardan gelen bilgiyi işleyerek sağladığı bilişsel kontrolün bozulmasına bağlı gelişiyor olabilir.

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Cite This Article

ÖZAŞKINLI, S., IŞIKLI, S., EKER, Ç., GÜLEÇ, F. (2022). Cerabellar cognitive affective syndrome. Türk Nöroloji Dergisi, Cilt: 13 - Sayı: 5, 333–338. https://ajindex.com/articles/637103

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