Journals / Türk Nöroloji Dergisi / 2007 / Cilt: 13 - Sayı: 5

Comparison of the blood cholesterol levels with magnetic resonance imaging activity in relapsing remitting multiple sclerosis

Relapsing retmitting multipl sklerozda serum kolesterol düzeyi ile manyetik rezonans görüntüleme aktivasyonunun karşılaştırılması

Pages
325–332
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

RESULTS: There was a significant correlation between the mean cholesterol levels and mean number of the lesions with contrast enhancement in MS patients (p

📌 3 Key Takeaways

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Objective & Hypothesis:OBJECTIVE: Multipl sclerosis is characterized by the destruction myelin and lipid metabolism occuring in central nervous system.
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Key Findings & Data:OBJECTIVES: The present study was planned to investigate the relationship between the plasma lipid profile and disease activity in patients with relapsing remitting multiple sclerosis (RRMS).METHODS: In 27 RRMS patients, cranial magnetic resonance imaging (MRI) was performed monthly, during the 6 months.
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Conclusion & Impact:RESULTS: There was a significant correlation between the mean cholesterol levels and mean number of the lesions with contrast enhancement in MS patients (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: Multipl sclerosis is characterized by the destruction myelin and lipid metabolism occuring in central nervous system. OBJECTIVES: The present study was planned to investigate the relationship between the plasma lipid profile and disease activity in patients with relapsing remitting multiple sclerosis (RRMS).METHODS: In 27 RRMS patients, cranial magnetic resonance imaging (MRI) was performed monthly, during the 6 months. Within the same day, blood samples were collected and neurological examinations were done. Number of the lesions with contrast enhancement were determined. Levels of the plasma cholesterol, triglceride, low density lipoprotein (LDL) and high density lipoprotein (HDL) were measuered. As a control group 18 persons without systemic and neurological disease were choosen. Blood samples were performed once. Comparision was made between the mean cholesterol, triglceride, LDL, HDL levels and, mean number of the lesions with contrast enhancement in MS patients. RESULTS: There was a significant correlation between the mean cholesterol levels and mean number of the lesions with contrast enhancement in MS patients (p

Özet

AMAÇ: Multipl skleroz, santral sinir sisteminde lipit metabolizmasında belirgin değişiklikler gösteren miyelin yıkımı ile karakterize bir hastalıktır. AMAÇ: Bu çalışmada, Relapsing Remitting Multipl Skleroz (RRMS)’lu hastalarda plazma lipit profili ile hastalık aktivasyonu arasındaki ilişki araştırıldı.YÖNTEMLER: 27 RRMS’li her hastaya 6 ay boyunca, ayda bir beyin manyetik rezonans görüntüleme (MRG) çekildi. Aynı gün içerisinde kan örnekleri alınarak, nörolojik muayeneleri yapıldı. Serebral MRG’de kontrast tutan lezyon sayısı saptandı. Kan örneklerinden plazma kolesterol, trigliserit, düşük dansiteli lipoprotein (LDL), yüksek dansiteli lipoprotein (HDL) seviyeleri ölçüldü. Sistemik ve nörolojik bir hastalığı olmayan 18 kişi kontrol grubu olarak alındı. Kontrol grubunun kan örnekleri bir kez alındı. Hastalarda kolesterol, trigliserit, LDL, HDL ortalama seviyeleri ile kontrast tutan lezyonların ortalama sayısı karşılaştırıldı. BULGULAR: MS grubunda kolesterol ortalama düzeyleri ile kontrast tutan lezyonların ortalama sayıları arasında anlamlı bir korelasyon bulundu (p

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Cite This Article

ERDOĞAN, S., YILMAZ, Z., CANTÜRK, İ. A., CANDAN, F., YILDIZ, N., IŞIK, N. (2022). Comparison of the blood cholesterol levels with magnetic resonance imaging activity in relapsing remitting multiple sclerosis. Türk Nöroloji Dergisi, Cilt: 13 - Sayı: 5, 325–332. https://ajindex.com/articles/637102

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