Journals / Türk Nöroloji Dergisi / 2008 / Cilt: 14 - Sayı: 2

Acute transverse myelitis with tertiary spinal syphilis: Case report

Akut transvers miyelite neden olan tersiyer spinal sifiliz tablosu: Olgu sunumu

Pages
121–127
Publication Date
2022-11-05
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

CASE: A 61 years old man presented with acute paraparesis, hyperestesia below level of T9 dermatom, fecal and uriner retantion.CONCLUSION: Our case is presented due to rare manifestation of syphilis like spinal myelitis with acute paraparesia and concomitant cardiac, cerebral, renal, aortic and retinal involvement by syphilis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Scientific BACKGROUND: Syphilis is an systemic infection that can effect the central nervous system in all stages.
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Key Findings & Data:OBJECTIVE: With the introduction of penicillin, effects of syphilis on central nervous system are decreased.
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Conclusion & Impact:CASE: A 61 years old man presented with acute paraparesis, hyperestesia below level of T9 dermatom, fecal and uriner retantion.CONCLUSION: Our case is presented due to rare manifestation of syphilis like spinal myelitis with acute paraparesia and concomitant cardiac, cerebral, renal, aortic and retinal involvement by syphilis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Scientific BACKGROUND: Syphilis is an systemic infection that can effect the central nervous system in all stages. Without treatment, it reaches the primary, secondary and tertiary stages, it also affects heart, central nervous system and other organs. OBJECTIVE: With the introduction of penicillin, effects of syphilis on central nervous system are decreased. Spinal cord involvement is very rare manifestation of syphilis. Syphilis should be kept in mind in transverse myelitis cases that presented with acute paraparesis. CASE: A 61 years old man presented with acute paraparesis, hyperestesia below level of T9 dermatom, fecal and uriner retantion.CONCLUSION: Our case is presented due to rare manifestation of syphilis like spinal myelitis with acute paraparesia and concomitant cardiac, cerebral, renal, aortic and retinal involvement by syphilis.

Özet

Bilimsel zemin: Sifiliz, seyrinin herhangi bir evresinde santral sinir sistemini etkileyebilen sistemik bir infeksiyondur. Tedavi edilmezse primer, sekonder ve tersiyer evrelere ilerler. Kalp, santral sinir sistemi ve diğer organ tutulumları ile seyreder.AMAÇ: Penisilinin kullanılmaya başlamasıyla, sifilize bağlı sık görülen santral sinir sistemi tutulumu azalmıştır. Spinal kord tutulumu ise, sifilizde oldukça nadir görülür. Sifiliz, akut paraparezili transvers miyelit olgularında, dışlanana kadar akılda tutulmalıdır.OLGU: 61 yaşında erkek hasta, akut paraparezi, T9 dermatomuna uyan duyu seviyesi (hiperestezi), idrar-gaita retansiyonu ile değerlendirildi. Görüntüleme, serolojik ve BOS incelemeleri sonucu tersiyer dönem sifiliz seyrinde gelişen transvers miyelit tablosu olarak kabul edildi. YORUM: Olgu, akut paraparezi ile giden sifilize sekonder spinal miyelit ve eşlik eden, serebral, kardiak, renal, aort ve retina gibi sifilizin diğer organ tutulumlarının olması nedeniyle ilgi çekiciydi. Ağrısız ve hiperakut gelişen sifilitik transversmiyelit olgusu, nadir görülmesi sebebiyle sunuldu.

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Cite This Article

ERDOĞAN, A., SARI, S. Ö. M., EYİİPGİL, T., KÖKEŞ, Ü., HIZ, F. (2022). Acute transverse myelitis with tertiary spinal syphilis: Case report. Türk Nöroloji Dergisi, Cilt: 14 - Sayı: 2, 121–127. https://ajindex.com/articles/637055

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References (17)

  1. Allan H. Ropper, Robert H. Brown. Neurosyphilis. Adams and Victor’s Principles Of Neurology. Eight Edition. 2005; Chapter 32, part 4:614-618
  2. Vaidas Matijosaitis, Antanas Vaitkus. Neurosyphilis manifesting as spinal transverse myelitis. Medicina (Kaunas) 2006;42(5) 401-404
  3. Prabhakar S, Syal P. Non-Compressive Myelopathy: Clinical and radiological study. Neural India 1999;47:294-9
  4. British Association for sexual health and HIV; UK Nat›onal Guidelines for the management of late syphilis 2005;2) (bradley)
  5. Larsen SA, Steiner BM, Rudolph AH. Laboratory diagnosis and interpretation of tests for syphilis. Clin Microbiol Rev 1995;8:1-21
  6. Sexually transmitted diseases treatment guidelines 2002. Centers for Disease Control and Prevention. MMWR Morb Mortal Wkly Rep 2002:51(RR-6):18-25, 28-30
  7. Brown DL, Frank JE. Diagnosis and management of syphilis.Am. FAM. Pyhsicans 2003 jul 15;68(2);283-90
  8. Cintron R, Pachner AR. Spirochetal disease of nervous system. Curr Opin Neurol 1994. Jun;7(3);217-22
  9. Kent ME, Romanelli F. Reexamining Syphilis: An Update on Epidemiology, Clinical Manifestations, and Management (February)(CE). Ann Pharmacother. 2008 Jan 22
  10. Fadil H, Kelley RE, Gonzalez-Toledo E; Differential diagnosis of multiple sclerosis. Int Rev Neurobiol 2007;79:393-422
  11. Marra CM, Maxwell CL, Smith SL, et al. Cerebrospinal fluid abnormalities in patient with syphilis; association with clinical and laboratory features J Infect Dis 2004 Feb 1;189(3);369-76
  12. Carlok Bazan, Manohar Aribandi; Syphilis. Spinal Cord and ‹ntradural Disease. Edelman Volume 2, Chapter 69:2179
  13. Renato Adam Mendonca; Syphilis. Spine and spinal Cord. Scott W. atlas. Volume 2 part 4:1918
  14. Nörosifilizde BOS kriterleri (British association for sexual health and HIV; UK National guideline for the management of late syphilis. 2005;2
  15. Landi G, Villani F, Anzalone N: Variable Angiographic Findings In Patients With Stroke And Neurosyphilis. Stroke 1990 Feb;21(2);333-8
  16. Zetola NM, Engelman J, Jensen TP, Klausner JD. Syphilis in the United States: an update for clinicians with an emphasis on HIV coinfection. Mayo Clin Proc 2007 Sep;82(9):1091-102
  17. Peng F, Hu X, Zhong X. CT and MR findings in HIV-negative neurosyphilis. Eur J Radiol 2007 Jul 10.