Journals / Türk Nöroloji Dergisi / 2020 / Cilt: 26 - Sayı: 4

Orolingual Angioedema After Intravenous Tissue Plasminogen Activator in a Patient with Insular Cortex Ischemia: A Case Report

İnsular Korteks İskemisi Olan Hastada İntravenöz Doku Plazminojen Aktivatörü Sonrası Gelişen Orolingual Anjiyoödem: Olgu Sunumu

Pages
346–348
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This report aims to reveal the relationship of this rare complication with the localization of the ischemia.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Intravenous tissue plasminogen activator (tPA) increases survival rates without sequelae in acute ischemic stroke.
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Key Findings & Data:An 80-year-old male patient was admitted with a sudden-onset speech disorder and loss of strength in his right arm, which started 3 hours ago.
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Conclusion & Impact:This report aims to reveal the relationship of this rare complication with the localization of the ischemia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Intravenous tissue plasminogen activator (tPA) increases survival rates without sequelae in acute ischemic stroke. Complications and management of this treatment have become more important with the increasing use of tPA. An 80-year-old male patient was admitted with a sudden-onset speech disorder and loss of strength in his right arm, which started 3 hours ago. Magnetic resonance imaging revealed acute ischemia localized in the left insular cortex. Lip and tongue swelling, difficulty in speaking, and deepening in voice were observed in the 30th minute of infusion. There was mild respiratory distress. Orolingual angioedema was diagnosed. He completely recovered after treatment. Angioedema is a rare but potentially life-threatening complication of tPA. When this clinical symptom occurs, it should be recognized and treated quickly. This report aims to reveal the relationship of this rare complication with the localization of the ischemia.

Özet

Akut iskemik inmede intravenöz doku plazminojen aktivatörü (tPA) sekelsiz sağkalım oranını artırmaktadır. Artan tPA kullanımı ile bu tedavinin komplikasyonları ve yönetimi daha önemli hale gelmiştir. Seksen yaşında erkek hasta 3 saat önce ani başlayan konuşma bozukluğu ve sağ kolda güç kaybı nedeniyle başvurdu. Manyetik rezonans görüntülemede sol insular kortekse uyan lokalizasyonda akut iskemi saptandı. İnfüzyonun 30. dakikasında dilde ve dudakta şişkinlik, konuşurken zorlanma ve seste kabalaşma gözlendi. Hafif solunum sıkıntısı saptandı. Orolingual anjiyoödem tanısı konuldu. Tedavi sonrası hasta tamamen düzeldi. Anjiyoödem tPA’nın nadir ancak potansiyel olarak yaşamı tehdit edici bir komplikasyonudur. Bu klinik semptomun hızlı bir şekilde tanınması ve tedavi edilmesi gerekir. Bu nadir komplikasyonun özellikle iskemik alanın lokalizasyonu ile ilişkisinin ortaya konulması amaçlanmıştır.

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Cite This Article

ÖZTÜRK, Ş., EREN, F., YILDOĞAN, A. T. (2022). Orolingual Angioedema After Intravenous Tissue Plasminogen Activator in a Patient with Insular Cortex Ischemia: A Case Report. Türk Nöroloji Dergisi, Cilt: 26 - Sayı: 4, 346–348. https://ajindex.com/articles/636646

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