Journals / Türk Nöroloji Dergisi / 2020 / Cilt: 26 - Sayı: 4

Evaluation of Sensory Nerve Conduction Studies and Hematologic Parameters in Restless Legs Syndrome

Huzursuz Bacaklar Sendromunda Duysal Sinir İletim Çalışmaları ve Hematolojik Parametrelerin Değerlendirilmesi

Pages
292–296
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

However, there was no correlation between ferritin levels and nerve conduction.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Restless legs syndrome (RLS) presents with sensory symptoms such as burning in the legs, patients want to move their legs.
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Key Findings & Data:The aim of this study was to investigate the relationship between sensory nerve conduction and hematologic parameters in RLS.Materials and Methods: Forty-five patients with RLS and 45 healthy controls were included in the study.
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Conclusion & Impact:However, there was no correlation between ferritin levels and nerve conduction.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Restless legs syndrome (RLS) presents with sensory symptoms such as burning in the legs, patients want to move their legs. Symptoms become apparent at rest and at night. The aim of this study was to investigate the relationship between sensory nerve conduction and hematologic parameters in RLS.Materials and Methods: Forty-five patients with RLS and 45 healthy controls were included in the study. Age, sex, and chronic diseases of the patients were questioned. Hemoglobin, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), and ferritin values were recorded. Ulnar, median, and sural sensory nerve amplitude, latency and conduction velocity were evaluated in a electroneuromyography laboratory. Data were analyzed using descriptive, parametric and nonparametric tests with the SPSS 21 software.Results: There were 22 (49%) female and 23 (51%) male patients with RLS in the study. The mean age was 57.31±14.47 years. Mean blood values were as follows: Hemoglobin (g/dl) 14.06±1.88; MCV (fl) 85.70 (55.7-96.5); MCH (pg) 28.45 (17.6-32.5), and ferritin (ng/ml) 31.30 (4-848). There was no difference in terms of blood values between RLS and control group (p>0.05). Sural nerve conduction velocity was slower in patients with RLS (p=0.01). Sural nerve latency was longer (p=0.01). Other nerve conduction parameters were equal in the study and control groups (p>0.05)Conclusion: Central nervous system dopaminergic mechanisms, genetic transmission, and low ferritin levels are the main factors in the pathogenesis of RLS. There is less focus on the peripheral nervous system. In this study, sural nerve conduction velocity and latency were associated with RLS. However, there was no correlation between ferritin levels and nerve conduction.

Özet

Amaç: Huzursuz bacaklar sendromu (HBS) bacaklarda yanma gibi duysal yakınmalar ile ortaya çıkan bir hastalıktır. Hastalar bacaklarını hareket ettirmek isterler. Semptomlar istirahatle ve geceleri belirginleşir. Bu çalışma ile HBS’de duysal sinir iletimlerinin hematolojik kan parametreleri ile ilişkisinin incelenmesi amaçlanmıştır.Gereç ve Yöntem: Çalışmaya 45 HBS’li hasta ve 45 sağlıklı kontrol dahil edildi. Hastaların yaş, cinsiyet ve kronik hastalıkları sorgulandı. Hemoglobin, ortalama korpusküler hacim (MCV), ortalama korpusküler hemoglobin (MCH), ortalama korpusküler hemoglobin konsantrasyonu (MCHC) ve ferritin değerleri kaydedildi. Ulnar, medyan ve sural duysal sinir amplitüd, latans ve iletim hızı elektronöromiyografi laboratuvarında değerlendirildi. Veriler SPSS 21 kullanılarak tanımlayıcı, parametrik ve nonparametrik testler ile analiz edildi.Bulgular: Çalışmada 22 (%49) kadın ve 23 (%51) erkek HBS’li hasta vardı. Yaş ortalaması 57,31±14,47 yıl idi. Hemoglobin (g/dl) 14,06±1,88; MCV (fl) 85,70 (55,7-96,5); MCH (pg) 28,45 (17,6-32,5) ve ferritin (ng/ml) 31,30 (4-848) seviyelerindeydi. HBS ve kontrol grubu arasında kan değerleri açısından fark saptanmadı (p>0,05). Sural sinir iletim hızı HBS’li hastalarda daha düşüktü (p=0,01). Sural sinir latansı daha uzundu (p=0,01). Diğer sinir iletimleri hasta ve kontrol grubunda benzerdi (p>0,05).Sonuç: HBS patogenezinde santral sinir sistemi dopaminerjik mekanizmaları, genetik geçiş ve düşük ferritin değerleri ön plandadır. Periferik sinir sistemi üzerinde daha az durulmaktadır. Bu çalışmada HBS hastalığı ile sural sinir iletim hızı ve latansı arasında ilişki olduğu belirlenmiştir. Ancak ferritin seviyesi ve sinir iletimleri arasında ilişki saptanmamıştır.

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Cite This Article

ÖZTÜRK, Ş., EREN, F., DEMİR, A. (2022). Evaluation of Sensory Nerve Conduction Studies and Hematologic Parameters in Restless Legs Syndrome. Türk Nöroloji Dergisi, Cilt: 26 - Sayı: 4, 292–296. https://ajindex.com/articles/636635

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