Journals / Türk Nöroloji Dergisi / 2021 / Cilt: 27 - Sayı: 2

Changes in Optical Coherence Tomography Parameters in Patients with Unilateral Carotid Artery Stenosis

Tek Taraflı Karotis Arter Stenozlu Hastalarda Optik Koherans Tomografi Parametrelerindeki Değişiklikler

Pages
140–144
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusion: The decrease in retinal artery blood flow did not lead to morphologic or functional changes of the retina in symptomatic or asymptomatic carotid artery disease.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The retina layer belongs to the end-stream region of the internal carotid artery, and thus various ophthalmic symptoms can present in patients with carotid artery stenosis.
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Key Findings & Data:Results: A total of 28 patients with unilateral CAS (17 asymptomatic, 11 symptomatic) were recruited.
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Conclusion & Impact:Conclusion: The decrease in retinal artery blood flow did not lead to morphologic or functional changes of the retina in symptomatic or asymptomatic carotid artery disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The retina layer belongs to the end-stream region of the internal carotid artery, and thus various ophthalmic symptoms can present in patients with carotid artery stenosis. The aim of this study was to examine the changes in retinal nerve fiber layer thickness (RNFLT), central macular thickness (CMT), retinal ganglion cell layer (RGCL), and choroidal thickness (CT) in patients who had unilateral (symptomatic or asymptomatic) carotid artery stenosis (CAS) using optical coherence tomography (OCT). Materials and Methods: In this prospective observational study, patients with confirmed unilateral CAS (symptomatic or asymptomatic) in computed tomography angiography were recruited. RNFLT, CMT, and RGCL were compared using spectral domain-OCT. CT was analyzed using enhanced depth imaging- OCT. Results: A total of 28 patients with unilateral CAS (17 asymptomatic, 11 symptomatic) were recruited. There were no significant differences between the eye on the stenotic side and the fellow eye according to RNFLT, CMT, RGCL, and CT in the asymptomatic group (p=0.986, p=0.945, p=0.569, and p=0.796, respectively). Similarly, in the symptomatic group, no significant differences were found between the eye on the stenotic side and the fellow eye according to the same parameters (p=0.693, p=0.409, p=0.792, and p=0.597, respectively). When comparing the eyes on the stenotic sides in both groups, no significant differences were found (p=0.85, p=0.24, p=0.7, p=0.98 respectively). Conclusion: The decrease in retinal artery blood flow did not lead to morphologic or functional changes of the retina in symptomatic or asymptomatic carotid artery disease.

Özet

Amaç: Retina internal karotis arterin kanlandırdığı son akım bölgesidir ve bu nedenle karotis stenozlu hastalarda çeşitli oftalmik semptomlar görülebilir. Bu çalışmanın amacı, tek taraflı karotis arter stenozu olan hastalarda (semptomatik veya asemptomatik), optik koherans tomografi (OCT) ile retinal sinir lifi kalınlığı (RNFLT), santral maküler kalınlık (CMT), retinal ganglion hücre tabakası kalınlığı (RGCL) ve koroidal kalınlık (CT) değişikliklerini saptamaktır. Gereç ve Yöntem: Bu prospektif gözlemsel çalışmaya, bilgisayarlı tomografi anjiyografi ile doğrulanan tek taraflı karotis arter stenozu olan hastalar (semptomatik veya asemptomatik) dahil edildi. Spektral alan-OCT ile RNFLT, CMT ve RGCL; gelişmiş derinlik görüntüleme-OCT ile CT ölçüldü. Bulgular: Tek taraflı karotis arter stenozu olan 28 hasta (17 asemptomatik, 11 semptomatik) çalışmaya alındı. Asemptomatik grupta, stenotik taraftaki göz ile diğer göz karşılaştırıldığında, RNFLT, CMT, RGCL ve CT değerleri arasında anlamlı fark saptanmadı (sırasıyla; p=0,986, p=0,945, p=0,569, p=0,796). Benzer şekilde, semptomatik grupta da iki göz karşılaştırıldığında aynı değerler arasında anlamlı fark saptanmadı (sırasıyla; p=0,693, p=0,409, p=0,792, p=0,597). Stenozlu taraflardaki gözler karşılaştırıldığında da aynı değerler için anlamlı fark saptanmadı (sırasıyla; p=0,85, p=0,24, p=0,7, p=0,98). Sonuç: Bu çalışmada, semptomatik ve asemptomatik karotis arter stenozu olan hastalardaki retinal arter kan akımındaki azalma retinada morfolojik ya da fonksiyonel değişikliklere yol açmamıştır.

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Cite This Article

GÖKSU, E. Ö., YÜKSEL, B., DOĞAN, B., ÜNAL, A. C. (2022). Changes in Optical Coherence Tomography Parameters in Patients with Unilateral Carotid Artery Stenosis. Türk Nöroloji Dergisi, Cilt: 27 - Sayı: 2, 140–144. https://ajindex.com/articles/636605

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