Journals / Türk Nöroloji Dergisi / 2021 / Cilt: 27 - Sayı: 1

Transvers Myelitis Due to HSV-2 Infection in an Undiagnosed HIV Positive Patient

Tanı Almamış HİV Pozitif Hastada HSV-2 Enfeksiyonuna Bağlı Transvers Miyelit

Pages
91–94
Publication Date
2022-11-06
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Viral serology reveals the opportunistic infections underlying the disease thereby guiding therapeutic regimens.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Several disorders including inflammatory, ischemic, and metabolic can cause longitudinally extensive transverse myelopathy.
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Key Findings & Data:Herein, we describe a 49-year-old man who presented with acute paraparesis and urinary retention.
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Conclusion & Impact:Viral serology reveals the opportunistic infections underlying the disease thereby guiding therapeutic regimens.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Several disorders including inflammatory, ischemic, and metabolic can cause longitudinally extensive transverse myelopathy. HIV-associated spinal cord involvement is rare. It can be due to AIDS-associated myelopathy, or opportunistic infections such as cytomegalovirus and herpes simplex virus (HSV). Herein, we describe a 49-year-old man who presented with acute paraparesis and urinary retention. His spinal magnetic resonance imaging revealed extensive hyperintense signal in the long TR sequence throughout C2 to T12, especially in the posterior and lateral columns. Both HIV ELISA test and HSV-2 DNA polymerase chain reaction were positive. Despite treatment, his clinical condition deteriorated. Acute transverse myelopathy can be the initial manifestation of an asymptomatic undiagnosed HIV positive patient. Viral serology reveals the opportunistic infections underlying the disease thereby guiding therapeutic regimens.

Özet

Enflamatuvar, iskemik ve metabolik çok sayıda hastalık longitudinal uzun segment transvers miyelite neden olabilir. HIV enfeksiyonuna bağlı spinal tutulum nadirdir. Tutulum, AIDS ilişkili miyelopati ya da sitomegalovirüs ve herpes simpleks virüsü (HSV) gibi fırsatçı enfeksiyonlara bağlı gelişebilir. Olgumuz paraparezi ve üriner retansiyon kliniği ile başvuran 49 yaşında bir erkek hastadır. Hastanın spinal görüntülemelerinde özellikle posterolateral bölgede C2-T12 segmentleri arasında uzanan longitudinal geniş miyelopati tespit edilmiştir. HIV-ELISA testi ve HSV-2 DNA polimeraz zincir reaksiyonu pozitif saptanmıştır. Uygulanan medikal tedaviye rağmen hastanın kliniği progrese olmuştur. Akut transvers miyelopati, henüz tanı konmamış HIV pozitif bir hastada ilk bulgu olarak karşımıza çıkabilir. Viral seroloji altta yatan hastalığa bağlı fırsatçı enfeksiyonları tanımada ve uygulanacak tedavi kararında yol gösterici olacaktır.

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Cite This Article

SOYSAL, A., ÖZERDEN, M., ÇOBAN, E., SERİNDAĞ, H., GÜL, Z. B. (2022). Transvers Myelitis Due to HSV-2 Infection in an Undiagnosed HIV Positive Patient. Türk Nöroloji Dergisi, Cilt: 27 - Sayı: 1, 91–94. https://ajindex.com/articles/636592

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