Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2011 / Cilt: 20 - Sayı: 3

Akut antikor aracılı renal allograt rejeksiyonunda çift filtrasyon plazmaferez: Üç vaka bildirimi

Utility of double filtration plasmapheresis in acute antibody mediated renal allograft rejection: Report of three cases

Pages
301–303
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here we report three renal transplant recipients in whom DFPP was applied as a component of anti-rejection treatment regimen.

📌 3 Key Takeaways

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Objective & Hypothesis:Plasmapheresis is an extracorporeal procedure, which is often employed to rapidly lower circulating titers of autoantibodies, immune complexes or toxins.
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Key Findings & Data:There are two types of plasmapheresis namely, regular plasmapheresis (RPP) by centrifugation and membrane filtration, and double filtration plasmapheresis (DFPP) which is a special form of membrane filtration in which two membranes called as plasma separator and plasma fractionator are employed to filter macromolecules more selectively.
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Conclusion & Impact:Here we report three renal transplant recipients in whom DFPP was applied as a component of anti-rejection treatment regimen.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Plasmapheresis is an extracorporeal procedure, which is often employed to rapidly lower circulating titers of autoantibodies, immune complexes or toxins. There are two types of plasmapheresis namely, regular plasmapheresis (RPP) by centrifugation and membrane filtration, and double filtration plasmapheresis (DFPP) which is a special form of membrane filtration in which two membranes called as plasma separator and plasma fractionator are employed to filter macromolecules more selectively. DFPP have several advantages over RP. Despite widespread utilization of DFPP in the setting of ABO blood group incompatible kidney transplantation, there is no report regarding DFPP in patients with antibody mediated acute renal allograft rejection who are good candidates for beneficial effects of DFPP. Here we report three renal transplant recipients in whom DFPP was applied as a component of anti-rejection treatment regimen.

Özet

Plazmaferez, dolaşımdaki antikor, immün kompleks ve toksin düzeylerini hızla düşürmek için kullanılan bir ekstrakorporeal yöntemdir.İki tip plazmaferez bulunmaktadır: Santrifüj ve membran filtrasyonu ile yapılan regüler plazmaferez (RP) ve büyük moleküllerin daha selektif olarak filtre edildiği, plazma ayırıcısı ve plazma fraksiyoneri olarak adlandırılan iki membranın kullanıldığı özel bir filtrasyon şekli olan çift filtrasyon plazmaferezdir (ÇFP).ÇFP'nin RP'ye göre bazı avantajları vardır. ABO uyumsuzluğunda böbrek nakli uygulamasında ÇFP yaygın olarak kullanılmasına rağmen, ÇFP'nin faydalı etkileri için iyi bir aday olabilecek antikor aracılı akut renal allograft rejeksiyonu olan hastalarda ÇFP ile ilgili vaka bildirimi yoktur. Burada rejeksiyon tedavisinin bir parçası olarak ÇFP uygulanan üç renal transplant hastasını bildirmekteyiz.

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Cite This Article

BIYIK, Z., TÜRKMEN, K., SOLAK, Y., YEKSAN, M., ANIL, M., ATALAY, H., POLAT, İ. (2022). Akut antikor aracılı renal allograt rejeksiyonunda çift filtrasyon plazmaferez: Üç vaka bildirimi. Türk Nefroloji Diyaliz ve Transplantasyon Dergisi, Cilt: 20 - Sayı: 3, 301–303. https://ajindex.com/articles/636454

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References (1)

  1. Madore F: Plasmapheresis. Technical aspects and indications. Crit Care Clin 2002; 18: 375-392 2. Singh N, Pirsch J, Samaniego M: Antibody-mediated rejection: Treatment alternatives and outcomes. Transplant Rev (Orlando) 2009; 23: 34-46 3. Colvin RB: Antibody-mediated renal allograft rejection: Diagnosis and pathogenesis. J Am Soc Nephrol 2007; 18: 1046-1056 4. Colvin RB, Nickeleit V: Renal transplant pathology. In Jennette JC, Olson JL, Schwartz MM, Silva FG (eds). Pathology of the Kidney (6th ed). Philadelphia: Lippincott-Raven, 2006; 1347-1490 5. Shimmura H, Tanabe K, Ishikawa N, Tokumoto T, Fuchinoue S, Takahashi K, Toma H, Agishi T: Removal of anti-A/B antibodies with plasmapheresis in ABO-incompatible kidney transplantation. Ther Apher Dial 2000; 4: 395-398 6. Tanabe K: Double-fi ltration plasmapheresis. Transplantation 2007; 84(12): 30-32 7. Ramunni A, Lauletta G, Brescia P, Saliani MT, Montrone M, Chironna M, Sansonno D, Dammacco F, Coratelli P: Doublefi ltration plasmapheresis in the treatment of leg ulcers in cryoglobulinemia. J Clin Apher 2008; 23: 118-122 8. Hajime N, Michiko A, Atsunori K,Tatsuo K, Yuko N, Naoki O, Katsuhiko S: A case report of effi ciency of double fi ltration plasmapheresis in treatment of Goodpasture’s syndrome. Ther Apher Dial 2009; 13: 373-377 9. Ramunni A, De Robertis F, Brescia P, Saliani MT, Amosuro M, Prontera M, Dimonte E, Trojano M, Coratelli P: A case report of double fi ltration plasmapheresis in an acute episode of multiple sclerosis. Ther Apher Dial 2008; 12: 250-254 10. Agishi T, Kaneko I, Hasuo Y Hayasaka Y, Sanaka T, Ota K, Amemiya H, Sugino N, Abe M, Ono T, Kawai S, Yamane T: Double fi ltration plasmapheresis. 1980. Ther Apher Dial 2000; 4: 29-33 11. Mineshima M, Akiba T: Double fi ltration plasmapheresis in critical care. Ther Apher 2002; 6: 180-183 12. Siami GA, Siami FS: Membrane plasmapheresis in the United States: A review over the last 20 years. Ther Apher 2001; 5: 315-320