AI Summary & Key Takeaways
AI InsightResistant hospital infections, causing respiratory failure and systemic complications, were facilitated by a long history of hospitalization before transplantation, the presence of WG and immunosupression and were successfully treated with a multidisciplinary approach.a
📌 3 Key Takeaways
Abstract
Wegener's granulomatosis (WG) is a disorder that causes necrotizing granulomatosis vasculitis particularly of the upper respiratory tract, lung and kidney. A 43-year-old male who had been treated with hemodialysis because of renal insufficiency due to WG underwent live donor renal transplantation. Pulmonary infiltrates were detected on the postoperative 4th day and antibiotic therapy was started with a diagnosis of sepsis and pulmonary infection. Dialysis treatment was also started due to the degradation of renal function for the patient who was intubated during follow-up. Non-invasive mechanical ventilation (BiPAP) treatment was started after extubation. The graft and respiratory function improved during clinical follow-up. Resistant hospital infections, causing respiratory failure and systemic complications, were facilitated by a long history of hospitalization before transplantation, the presence of WG and immunosupression and were successfully treated with a multidisciplinary approach.a
Özet
Wegener granülomatozu (WG) özellikle üst solunum yolları, akciğer ve böbrekleri tutan nekrotizan granülomatoz vaskülite yol açan bir hastalıktır. WG'a bağlı renal yetmezlik tanısı ile hemodiyaliz tedavisi alan 43 yaşında erkek hastaya canlı donörden renal transplantasyon uygulandı. Postop 4. günde pulmoner infiltrasyon saptanması üzerine akciğer enfeksiyonu ve sepsis tanılarıyla antibiyoterapi başlandı. Takiplerinde entübe edilen hastaya renal işlevlerinin de bozulmasıyla diyaliz tedavisi başlandı. Ekstübe olduktan sonra non-invaziv mekanik ventilatör (BİPAP) tedavisi başlandı. Takiplerinde graft ve solunum işlevleri düzeldi. Transplantasyon öncesi hastanede uzun yatış öyküsü, WG varlığı ve immünsupresyonun kolaylaştırdığı sistemik komplikasyonlara ve solunum yetmezliğine neden olan dirençli hastane enfeksiyonu multidisipliner yaklaşımla başarıyla tedavi edildi.